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2IS1

Crystal structure of UvrD-DNA-SO4 complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0000717biological_processnucleotide-excision repair, DNA duplex unwinding
A0000725biological_processrecombinational repair
A0003677molecular_functionDNA binding
A0003678molecular_functionDNA helicase activity
A0004386molecular_functionhelicase activity
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006260biological_processDNA replication
A0006268biological_processDNA unwinding involved in DNA replication
A0006281biological_processDNA repair
A0006289biological_processnucleotide-excision repair
A0006298biological_processmismatch repair
A0006974biological_processDNA damage response
A0009314biological_processresponse to radiation
A0009432biological_processSOS response
A0015616molecular_functionDNA translocase activity
A0016787molecular_functionhydrolase activity
A0016853molecular_functionisomerase activity
A0016887molecular_functionATP hydrolysis activity
A0017116molecular_functionsingle-stranded DNA helicase activity
A0017117cellular_componentsingle-stranded DNA-dependent ATP-dependent DNA helicase complex
A0031297biological_processreplication fork processing
A0032508biological_processDNA duplex unwinding
A0033202cellular_componentDNA helicase complex
A0042803molecular_functionprotein homodimerization activity
A0043138molecular_function3'-5' DNA helicase activity
A0070581biological_processrolling circle DNA replication
A0070716biological_processmismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication
B0000166molecular_functionnucleotide binding
B0000717biological_processnucleotide-excision repair, DNA duplex unwinding
B0000725biological_processrecombinational repair
B0003677molecular_functionDNA binding
B0003678molecular_functionDNA helicase activity
B0004386molecular_functionhelicase activity
B0005515molecular_functionprotein binding
B0005524molecular_functionATP binding
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006260biological_processDNA replication
B0006268biological_processDNA unwinding involved in DNA replication
B0006281biological_processDNA repair
B0006289biological_processnucleotide-excision repair
B0006298biological_processmismatch repair
B0006974biological_processDNA damage response
B0009314biological_processresponse to radiation
B0009432biological_processSOS response
B0015616molecular_functionDNA translocase activity
B0016787molecular_functionhydrolase activity
B0016853molecular_functionisomerase activity
B0016887molecular_functionATP hydrolysis activity
B0017116molecular_functionsingle-stranded DNA helicase activity
B0017117cellular_componentsingle-stranded DNA-dependent ATP-dependent DNA helicase complex
B0031297biological_processreplication fork processing
B0032508biological_processDNA duplex unwinding
B0033202cellular_componentDNA helicase complex
B0042803molecular_functionprotein homodimerization activity
B0043138molecular_function3'-5' DNA helicase activity
B0070581biological_processrolling circle DNA replication
B0070716biological_processmismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE HG A 681
ChainResidue
ACYS322
AALA323
AGLU616
AARG645

site_idAC2
Number of Residues2
DetailsBINDING SITE FOR RESIDUE HG A 682
ChainResidue
AASN288
ACYS640

site_idAC3
Number of Residues2
DetailsBINDING SITE FOR RESIDUE HG A 683
ChainResidue
AARG22
ACYS52

site_idAC4
Number of Residues2
DetailsBINDING SITE FOR RESIDUE HG B 681
ChainResidue
BALA323
BCYS322

site_idAC5
Number of Residues2
DetailsBINDING SITE FOR RESIDUE HG B 682
ChainResidue
BASN288
BCYS640

site_idAC6
Number of Residues6
DetailsBINDING SITE FOR RESIDUE SO4 A 684
ChainResidue
AALA31
AGLN251
AARG284
AGLY564
AARG605
AGOL686

site_idAC7
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 B 683
ChainResidue
BALA31
BGLN251
BARG284
BARG605

site_idAC8
Number of Residues5
DetailsBINDING SITE FOR RESIDUE SO4 A 685
ChainResidue
AGLY34
ATHR36
AARG37
AARG73
AGOL686

site_idAC9
Number of Residues5
DetailsBINDING SITE FOR RESIDUE GOL A 686
ChainResidue
ALYS35
ATHR36
AGLU69
ASO4684
ASO4685

site_idBC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE GOL B 684
ChainResidue
BGLY34
BTHR36
BARG37
BARG73

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00560
ChainResidueDetails
AGLY32
BGLY32

site_idSWS_FT_FI2
Number of Residues2
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
AARG284
BARG284

218853

数据于2024-04-24公开中

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