2E9H

Solution structure of the eIF-5_eIF-2B domain from human Eukaryotic translation initiation factor 5

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003743	molecular_function	translation initiation factor activity
A	0006413	biological_process	translational initiation

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 301

Chain	Residue
A	CYS106
A	CYS109
A	CYS129
A	CYS132

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255

Chain	Residue	Details
A	GLY34

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site_id	SWS_FT_FI2
Number of Residues	1
Details	SITE: Arginine finger => ECO:0000269|PubMed:11166181

Chain	Residue	Details
A	ARG22

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
A	SER17

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