1XV8

Crystal Structure of Human Salivary Alpha-Amylase Dimer

GO（遺伝子オントロジー）由来の情報

鎖名	GO（遺伝子オントロジー）id	名前空間	内容
A	0003824	molecular_function	catalytic activity
A	0004556	molecular_function	alpha-amylase activity
A	0005509	molecular_function	calcium ion binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005975	biological_process	carbohydrate metabolic process
A	0008152	biological_process	metabolic process
A	0009311	biological_process	oligosaccharide metabolic process
A	0016160	molecular_function	amylase activity
A	0016787	molecular_function	hydrolase activity
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0031404	molecular_function	chloride ion binding
A	0043169	molecular_function	cation binding
A	0046872	molecular_function	metal ion binding
A	0070062	cellular_component	extracellular exosome
B	0003824	molecular_function	catalytic activity
B	0004556	molecular_function	alpha-amylase activity
B	0005509	molecular_function	calcium ion binding
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0005975	biological_process	carbohydrate metabolic process
B	0008152	biological_process	metabolic process
B	0009311	biological_process	oligosaccharide metabolic process
B	0016160	molecular_function	amylase activity
B	0016787	molecular_function	hydrolase activity
B	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
B	0031404	molecular_function	chloride ion binding
B	0043169	molecular_function	cation binding
B	0046872	molecular_function	metal ion binding
B	0070062	cellular_component	extracellular exosome

PDBデータベースに由来する情報

site_id	AC1
残基数	5
詳細	BINDING SITE FOR RESIDUE CA A 497

鎖名	残基
A	ASN100
A	ARG158
A	ASP167
A	HIS201
A	HOH510

---

site_id	AC2
残基数	5
詳細	BINDING SITE FOR RESIDUE CA B 497

鎖名	残基
B	HOH513
B	ASN100
B	ARG158
B	ASP167
B	HIS201

---

site_id	AC3
残基数	3
詳細	BINDING SITE FOR RESIDUE CL B 498

鎖名	残基
B	ARG195
B	ASN298
B	ARG337

---

site_id	AC4
残基数	3
詳細	BINDING SITE FOR RESIDUE CL A 498

鎖名	残基
A	ARG195
A	ASN298
A	ARG337

---

SwissProt/UniProtに記載されている蛋白質分子機能情報

site_id	SWS_FT_FI1
残基数	2
詳細	ACT_SITE: Nucleophile

鎖名	残基	詳細
A	ASP197
B	ASP197

---

site_id	SWS_FT_FI2
残基数	2
詳細	ACT_SITE: Proton donor

鎖名	残基	詳細
A	GLU233
B	GLU233

---

site_id	SWS_FT_FI3
残基数	14
詳細	BINDING: BINDING => ECO:0000269|PubMed:12527308, ECO:0000269|PubMed:15299664, ECO:0007744|PDB:1SMD

鎖名	残基	詳細
A	ASN100
B	ASP167
B	ARG195
B	HIS201
B	ASN298
B	ARG337
A	ARG158
A	ASP167
A	ARG195
A	HIS201
A	ASN298
A	ARG337
B	ASN100
B	ARG158

---

site_id	SWS_FT_FI4
残基数	2
詳細	SITE: Transition state stabilizer => ECO:0000250|UniProtKB:P04746

鎖名	残基	詳細
A	ASP300
B	ASP300

---

site_id	SWS_FT_FI5
残基数	2
詳細	MOD_RES: Pyrrolidone carboxylic acid => ECO:0000250|UniProtKB:P00687

鎖名	残基	詳細
A	PCA1
B	PCA1

---

site_id	SWS_FT_FI6
残基数	4
詳細	MOD_RES: Deamidated asparagine; partial => ECO:0000269|PubMed:1710976

鎖名	残基	詳細
A	ASN350
A	ASN459
B	ASN350
B	ASN459

---

site_id	SWS_FT_FI7
残基数	2
詳細	MOD_RES: Deamidated asparagine; partial; alternate => ECO:0000269|PubMed:1710976

鎖名	残基	詳細
A	ASN412
B	ASN412

---

site_id	SWS_FT_FI8
残基数	2
詳細	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16740002, ECO:0000269|PubMed:1710976

鎖名	残基	詳細
A	ASN412
B	ASN412

---

site_id	SWS_FT_FI9
残基数	2
詳細	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

鎖名	残基	詳細
A	ASN461
B	ASN461

---