1SQ5
Crystal Structure of E. coli Pantothenate kinase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004594 | molecular_function | pantothenate kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0015937 | biological_process | coenzyme A biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016310 | biological_process | phosphorylation |
| A | 0016740 | molecular_function | transferase activity |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0050165 | molecular_function | pantetheine kinase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004594 | molecular_function | pantothenate kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0015937 | biological_process | coenzyme A biosynthetic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016310 | biological_process | phosphorylation |
| B | 0016740 | molecular_function | transferase activity |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0050165 | molecular_function | pantetheine kinase activity |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004594 | molecular_function | pantothenate kinase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0015937 | biological_process | coenzyme A biosynthetic process |
| C | 0016301 | molecular_function | kinase activity |
| C | 0016310 | biological_process | phosphorylation |
| C | 0016740 | molecular_function | transferase activity |
| C | 0042803 | molecular_function | protein homodimerization activity |
| C | 0050165 | molecular_function | pantetheine kinase activity |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0004594 | molecular_function | pantothenate kinase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0015937 | biological_process | coenzyme A biosynthetic process |
| D | 0016301 | molecular_function | kinase activity |
| D | 0016310 | biological_process | phosphorylation |
| D | 0016740 | molecular_function | transferase activity |
| D | 0042803 | molecular_function | protein homodimerization activity |
| D | 0050165 | molecular_function | pantetheine kinase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE PAU A 6001 |
| Chain | Residue |
| A | ASP1127 |
| A | HOH7278 |
| A | HOH7588 |
| A | HOH7601 |
| A | HOH7650 |
| A | LYS1145 |
| A | GLY1146 |
| A | HIS1177 |
| A | LEU1201 |
| A | TYR1240 |
| A | ILE1281 |
| A | ASN1282 |
| A | HOH7117 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PAU C 6002 |
| Chain | Residue |
| C | ASP3127 |
| C | LYS3145 |
| C | GLY3146 |
| C | HIS3177 |
| C | TYR3240 |
| C | ASN3282 |
| C | HOH7257 |
| C | HOH7262 |
| C | HOH7263 |
| C | HOH7729 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PAU B 6003 |
| Chain | Residue |
| B | ASP2127 |
| B | LYS2145 |
| B | GLY2146 |
| B | HIS2177 |
| B | TYR2240 |
| B | ASN2282 |
| B | HOH7277 |
| B | HOH7311 |
| B | HOH7326 |
| B | HOH7662 |
| B | HOH7759 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PAU D 6004 |
| Chain | Residue |
| D | ASP4127 |
| D | LYS4145 |
| D | GLY4146 |
| D | HIS4177 |
| D | TYR4240 |
| D | ASN4282 |
| D | HOH7391 |
| D | HOH7449 |
| D | HOH7487 |
| D | HOH7493 |
| D | HOH7540 |
| site_id | AC5 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE ADP A 5001 |
| Chain | Residue |
| A | ASN1043 |
| A | ASP1045 |
| A | LEU1046 |
| A | SER1096 |
| A | ALA1098 |
| A | VAL1099 |
| A | GLY1100 |
| A | LYS1101 |
| A | SER1102 |
| A | THR1103 |
| A | ARG1243 |
| A | LYS1303 |
| A | HIS1307 |
| A | HOH7100 |
| A | HOH7255 |
| A | HOH7281 |
| A | HOH7496 |
| A | HOH7533 |
| A | HOH7575 |
| A | HOH7672 |
| site_id | AC6 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE ADP B 5002 |
| Chain | Residue |
| B | ASN2043 |
| B | ASP2045 |
| B | LEU2046 |
| B | SER2096 |
| B | ALA2098 |
| B | VAL2099 |
| B | GLY2100 |
| B | LYS2101 |
| B | SER2102 |
| B | THR2103 |
| B | ARG2243 |
| B | LYS2303 |
| B | HIS2307 |
| B | HOH7252 |
| B | HOH7258 |
| B | HOH7267 |
| B | HOH7268 |
| B | HOH7293 |
| B | HOH7383 |
| B | HOH7502 |
| B | HOH7781 |
| site_id | AC7 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE ADP C 5003 |
| Chain | Residue |
| C | HOH7273 |
| C | HOH7279 |
| C | HOH7291 |
| C | HOH7300 |
| C | HOH7331 |
| C | HOH7494 |
| C | HOH7670 |
| C | ASN3043 |
| C | LEU3046 |
| C | VAL3097 |
| C | ALA3098 |
| C | VAL3099 |
| C | GLY3100 |
| C | LYS3101 |
| C | SER3102 |
| C | THR3103 |
| C | ARG3243 |
| C | LYS3303 |
| C | HIS3307 |
| C | HOH7253 |
| site_id | AC8 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE ADP D 5004 |
| Chain | Residue |
| D | ASN4043 |
| D | ASP4045 |
| D | LEU4046 |
| D | SER4096 |
| D | ALA4098 |
| D | VAL4099 |
| D | GLY4100 |
| D | LYS4101 |
| D | SER4102 |
| D | THR4103 |
| D | ARG4243 |
| D | LYS4303 |
| D | HIS4307 |
| D | HOH7254 |
| D | HOH7323 |
| D | HOH7391 |
| D | HOH7446 |
| D | HOH7600 |
| D | HOH7766 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255 |
| Chain | Residue | Details |
| A | GLY1095 | |
| B | GLY2095 | |
| C | GLY3095 | |
| D | GLY4095 |
