1P74

CRYSTAL STRUCTURE OF SHIKIMATE DEHYDROGENASE (AROE) FROM HAEMOPHILUS INFLUENZAE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004764	molecular_function	shikimate 3-dehydrogenase (NADP+) activity
A	0005829	cellular_component	cytosol
A	0008652	biological_process	amino acid biosynthetic process
A	0009073	biological_process	aromatic amino acid family biosynthetic process
A	0009423	biological_process	chorismate biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0019632	biological_process	shikimate metabolic process
A	0050661	molecular_function	NADP binding
B	0004764	molecular_function	shikimate 3-dehydrogenase (NADP+) activity
B	0005829	cellular_component	cytosol
B	0008652	biological_process	amino acid biosynthetic process
B	0009073	biological_process	aromatic amino acid family biosynthetic process
B	0009423	biological_process	chorismate biosynthetic process
B	0016491	molecular_function	oxidoreductase activity
B	0019632	biological_process	shikimate metabolic process
B	0050661	molecular_function	NADP binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_00222

Chain	Residue	Details
A	LYS65
B	LYS65

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site_id	SWS_FT_FI2
Number of Residues	14
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00222

Chain	Residue	Details
A	SER14
B	ASN86
B	ASP102
B	MET213
B	TYR215
B	GLY238
A	THR61
A	ASN86
A	ASP102
A	MET213
A	TYR215
A	GLY238
B	SER14
B	THR61

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site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00222, ECO:0000269|PubMed:12837789

Chain	Residue	Details
A	GLY126
A	ASN149
B	GLY126
B	ASN149

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site_id	SWS_FT_FI4
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:12837789

Chain	Residue	Details
A	SER189
B	SER189

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