1NMC
COMPLEX BETWEEN NC10 ANTI-INFLUENZA VIRUS NEURAMINIDASE SINGLE CHAIN ANTIBODY WITH A 15 RESIDUE LINKER AND INFLUENZA VIRUS NEURAMINIDASE
GO（遺伝子オントロジー）由来の情報
| 鎖名 | GO（遺伝子オントロジー）id | 名前空間 | 内容 |
| A | 0004308 | molecular_function | exo-alpha-sialidase activity |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0016020 | cellular_component | membrane |
| A | 0033644 | cellular_component | host cell membrane |
| A | 0046761 | biological_process | viral budding from plasma membrane |
| A | 0055036 | cellular_component | virion membrane |
| N | 0004308 | molecular_function | exo-alpha-sialidase activity |
| N | 0005975 | biological_process | carbohydrate metabolic process |
| N | 0016020 | cellular_component | membrane |
| N | 0033644 | cellular_component | host cell membrane |
| N | 0046761 | biological_process | viral budding from plasma membrane |
| N | 0055036 | cellular_component | virion membrane |
SwissProt/UniProtに記載されている蛋白質分子機能情報
| site_id | SWS_FT_FI1 |
| 残基数 | 2 |
| 詳細 | ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_04071 |
| 鎖名 | 残基 | 詳細 |
| N | ASP151 | |
| A | ASP151 |
| site_id | SWS_FT_FI2 |
| 残基数 | 2 |
| 詳細 | ACT_SITE: Nucleophile => ECO:0000255|HAMAP-Rule:MF_04071 |
| 鎖名 | 残基 | 詳細 |
| N | TYR406 | |
| A | TYR406 |
| site_id | SWS_FT_FI3 |
| 残基数 | 10 |
| 詳細 | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_04071 |
| 鎖名 | 残基 | 詳細 |
| N | ARG118 | |
| A | ARG371 | |
| N | ARG152 | |
| N | GLU276 | |
| N | ARG292 | |
| N | ARG371 | |
| A | ARG118 | |
| A | ARG152 | |
| A | GLU276 | |
| A | ARG292 |
| site_id | SWS_FT_FI4 |
| 残基数 | 8 |
| 詳細 | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_04071, ECO:0000269|PubMed:23429702, ECO:0000269|PubMed:7549872, ECO:0000269|PubMed:8371267, ECO:0000269|PubMed:9342319 |
| 鎖名 | 残基 | 詳細 |
| N | ASP293 | |
| N | GLY297 | |
| N | ASP324 | |
| N | ASN347 | |
| A | ASP293 | |
| A | GLY297 | |
| A | ASP324 | |
| A | ASN347 |
| site_id | SWS_FT_FI5 |
| 残基数 | 6 |
| 詳細 | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04071, ECO:0000269|PubMed:23429702, ECO:0000269|PubMed:7549872, ECO:0000269|PubMed:9342319 |
| 鎖名 | 残基 | 詳細 |
| N | ASN86 | |
| N | ASN146 | |
| N | ASN200 | |
| A | ASN86 | |
| A | ASN146 | |
| A | ASN200 |
CSAにおける酵素触媒機能の情報
| site_id | MCSA1 |
| 残基数 | 5 |
| 詳細 | M-CSA 828 |
| 鎖名 | 残基 | 詳細 |
| N | ASP151 | activator, electrostatic stabiliser, increase acidity, increase nucleophilicity, proton acceptor, proton donor |
| N | GLU277 | activator, electrostatic stabiliser, increase nucleophilicity, promote heterolysis, proton acceptor, proton donor |
| N | ARG292 | electrostatic stabiliser |
| N | ARG371 | electrostatic stabiliser |
| N | TYR406 | electrostatic stabiliser, nucleofuge, nucleophile, proton acceptor, proton donor |
| site_id | MCSA2 |
| 残基数 | 5 |
| 詳細 | M-CSA 828 |
| 鎖名 | 残基 | 詳細 |
| A | ASP151 | activator, electrostatic stabiliser, increase acidity, increase nucleophilicity, proton acceptor, proton donor |
| A | GLU277 | activator, electrostatic stabiliser, increase nucleophilicity, promote heterolysis, proton acceptor, proton donor |
| A | ARG292 | electrostatic stabiliser |
| A | ARG371 | electrostatic stabiliser |
| A | TYR406 | electrostatic stabiliser, nucleofuge, nucleophile, proton acceptor, proton donor |
