Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004459 | molecular_function | L-lactate dehydrogenase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006089 | biological_process | lactate metabolic process |
| A | 0006090 | biological_process | pyruvate metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0019752 | biological_process | carboxylic acid metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 41 |
| Details | BINDING SITE FOR RESIDUE NAD A 330 |
| Chain | Residue |
| A | VAL28 |
| A | LYS57 |
| A | LEU58 |
| A | LYS59 |
| A | GLY60 |
| A | GLU61 |
| A | SER79 |
| A | LYS81 |
| A | ASP82 |
| A | TYR83 |
| A | TYR83 |
| A | GLY29 |
| A | THR95 |
| A | ALA96 |
| A | ALA98 |
| A | ARG99 |
| A | VAL136 |
| A | SER137 |
| A | ASN138 |
| A | SER161 |
| A | HIS193 |
| A | LEU241 |
| A | ASP52 |
| A | LYS242 |
| A | TYR244 |
| A | SER246 |
| A | OXM331 |
| A | HOH347 |
| A | HOH353 |
| A | HOH359 |
| A | HOH373 |
| A | HOH384 |
| A | HOH493 |
| A | VAL53 |
| A | HOH496 |
| A | HOH497 |
| A | VAL53 |
| A | MET54 |
| A | MET54 |
| A | GLU55 |
| A | ASP56 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE OXM A 331 |
| Chain | Residue |
| A | ARG106 |
| A | HIS193 |
| A | ALA235 |
| A | NAD330 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE OXM A 332 |
| Chain | Residue |
| A | GLN111 |
| A | ARG171 |
| A | HIS186 |
| A | VAL291 |
| A | HOH335 |
| A | HOH424 |
| A | HOH439 |
Functional Information from PROSITE/UniProt
| site_id | PS00064 |
| Number of Residues | 7 |
| Details | L_LDH L-lactate dehydrogenase active site. IGEHGDS |
| Chain | Residue | Details |
| A | ILE190-SER196 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton acceptor |
| Chain | Residue | Details |
| A | GLY194 | |
| Chain | Residue | Details |
| A | ALA30 | |
| A | GLN100 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | LEU107 | |
| A | PRO139 | |
| A | ILE249 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | PHE170 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 584 |
| Chain | Residue | Details |
| A | LEU107 | electrostatic stabiliser |
| A | SER167 | enhance reactivity |
| A | PHE170 | electrostatic stabiliser |
| A | GLY194 | proton acceptor, proton donor |
