1GSF

GLUTATHIONE TRANSFERASE A1-1 COMPLEXED WITH ETHACRYNIC ACID

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GO(遺伝子オントロジー)由来の情報

鎖名GO(遺伝子オントロジー)id名前空間内容
A0005829cellular_componentcytosol
A0070062cellular_componentextracellular exosome
A0004602molecular_functionglutathione peroxidase activity
A0004364molecular_functionglutathione transferase activity
A0004769molecular_functionsteroid delta-isomerase activity
A0030855biological_processepithelial cell differentiation
A1901687biological_processglutathione derivative biosynthetic process
A0006749biological_processglutathione metabolic process
A0043651biological_processlinoleic acid metabolic process
A0006693biological_processprostaglandin metabolic process
A0006805biological_processxenobiotic metabolic process
B0005829cellular_componentcytosol
B0070062cellular_componentextracellular exosome
B0004602molecular_functionglutathione peroxidase activity
B0004364molecular_functionglutathione transferase activity
B0004769molecular_functionsteroid delta-isomerase activity
B0030855biological_processepithelial cell differentiation
B1901687biological_processglutathione derivative biosynthetic process
B0006749biological_processglutathione metabolic process
B0043651biological_processlinoleic acid metabolic process
B0006693biological_processprostaglandin metabolic process
B0006805biological_processxenobiotic metabolic process
C0005829cellular_componentcytosol
C0070062cellular_componentextracellular exosome
C0004602molecular_functionglutathione peroxidase activity
C0004364molecular_functionglutathione transferase activity
C0004769molecular_functionsteroid delta-isomerase activity
C0030855biological_processepithelial cell differentiation
C1901687biological_processglutathione derivative biosynthetic process
C0006749biological_processglutathione metabolic process
C0043651biological_processlinoleic acid metabolic process
C0006693biological_processprostaglandin metabolic process
C0006805biological_processxenobiotic metabolic process
D0005829cellular_componentcytosol
D0070062cellular_componentextracellular exosome
D0004602molecular_functionglutathione peroxidase activity
D0004364molecular_functionglutathione transferase activity
D0004769molecular_functionsteroid delta-isomerase activity
D0030855biological_processepithelial cell differentiation
D1901687biological_processglutathione derivative biosynthetic process
D0006749biological_processglutathione metabolic process
D0043651biological_processlinoleic acid metabolic process
D0006693biological_processprostaglandin metabolic process
D0006805biological_processxenobiotic metabolic process
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PDBデータベースに由来する情報

site_id残基数詳細
AC111BINDING SITE FOR RESIDUE EAA A 223
鎖名残基
ATYR9
APHE10
AGLY14
AARG15
AVAL55
ALEU107
AVAL111
AMET208
APHE220
AHOH271
AHOH288

AC211BINDING SITE FOR RESIDUE EAA B 223
鎖名残基
BTYR9
BPHE10
BGLY14
BARG15
BVAL55
BLEU107
BVAL111
BMET208
BPHE220
BHOH276
BHOH293

AC39BINDING SITE FOR RESIDUE EAA C 223
鎖名残基
CTYR9
CPHE10
CGLY14
CARG15
CVAL55
CLEU107
CVAL111
CMET208
CPHE220

AC49BINDING SITE FOR RESIDUE EAA D 223
鎖名残基
DTYR9
DPHE10
DGLY14
DARG15
DVAL55
DLEU107
DVAL111
DMET208
DPHE220

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「HETATM」原子の座標から抽出されたリガンド結合部位

site_id残基数詳細
EAA_1gsf_A_22317ETHACRYNIC ACID binding site
鎖名残基ligand
ATYR9-PHE10EAA: ETHACRYNIC ACID
AALA12EAA: ETHACRYNIC ACID
AGLY14-ARG15EAA: ETHACRYNIC ACID
AGLN54-PRO56EAA: ETHACRYNIC ACID
ALEU107-LEU108EAA: ETHACRYNIC ACID
APRO110-VAL111EAA: ETHACRYNIC ACID
AMET208EAA: ETHACRYNIC ACID
ALEU213EAA: ETHACRYNIC ACID
AALA216EAA: ETHACRYNIC ACID
APHE220EAA: ETHACRYNIC ACID
APHE222EAA: ETHACRYNIC ACID

EAA_1gsf_B_22317ETHACRYNIC ACID binding site
鎖名残基ligand
BTYR9-PHE10EAA: ETHACRYNIC ACID
BALA12EAA: ETHACRYNIC ACID
BGLY14-ARG15EAA: ETHACRYNIC ACID
BGLN54-PRO56EAA: ETHACRYNIC ACID
BLEU107-LEU108EAA: ETHACRYNIC ACID
BPRO110-VAL111EAA: ETHACRYNIC ACID
BMET208EAA: ETHACRYNIC ACID
BLEU213EAA: ETHACRYNIC ACID
BALA216EAA: ETHACRYNIC ACID
BPHE220EAA: ETHACRYNIC ACID
BPHE222EAA: ETHACRYNIC ACID

EAA_1gsf_C_22317ETHACRYNIC ACID binding site
鎖名残基ligand
CTYR9-PHE10EAA: ETHACRYNIC ACID
CALA12EAA: ETHACRYNIC ACID
CGLY14-ARG15EAA: ETHACRYNIC ACID
CGLN54-PRO56EAA: ETHACRYNIC ACID
CLEU107-LEU108EAA: ETHACRYNIC ACID
CPRO110-VAL111EAA: ETHACRYNIC ACID
CMET208EAA: ETHACRYNIC ACID
CLEU213EAA: ETHACRYNIC ACID
CALA216EAA: ETHACRYNIC ACID
CPHE220EAA: ETHACRYNIC ACID
CPHE222EAA: ETHACRYNIC ACID

EAA_1gsf_D_22317ETHACRYNIC ACID binding site
鎖名残基ligand
DTYR9-PHE10EAA: ETHACRYNIC ACID
DALA12EAA: ETHACRYNIC ACID
DGLY14-ARG15EAA: ETHACRYNIC ACID
DGLN54-PRO56EAA: ETHACRYNIC ACID
DLEU107-LEU108EAA: ETHACRYNIC ACID
DPRO110-VAL111EAA: ETHACRYNIC ACID
DMET208EAA: ETHACRYNIC ACID
DLEU213EAA: ETHACRYNIC ACID
DALA216EAA: ETHACRYNIC ACID
DPHE220EAA: ETHACRYNIC ACID
DPHE222EAA: ETHACRYNIC ACID

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UniProtにおけるモチーフ・データベースPROSITEからの機能情報

site_id残基数詳細
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SwissProt/UniProtに記載されている蛋白質分子機能情報

site_id残基数詳細
SWS_FT_FI12Glutathione.
鎖名残基詳細
ATYR8
AARG44

SWS_FT_FI22Glutathione.
鎖名残基詳細
BTYR8
BARG44

SWS_FT_FI32Glutathione.
鎖名残基詳細
CTYR8
CARG44

SWS_FT_FI42Glutathione.
鎖名残基詳細
DTYR8
DARG44

CSA11Annotated By Reference To The Literature 1oe8
鎖名残基詳細
ATYR9

CSA21Annotated By Reference To The Literature 1oe8
鎖名残基詳細
BTYR9

CSA31Annotated By Reference To The Literature 1oe8
鎖名残基詳細
CTYR9

CSA41Annotated By Reference To The Literature 1oe8
鎖名残基詳細
DTYR9

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CSAにおける酵素触媒機能の情報

site_id残基数詳細
CSA11Annotated By Reference To The Literature 1oe8
鎖名残基詳細
ATYR9

CSA21Annotated By Reference To The Literature 1oe8
鎖名残基詳細
BTYR9

CSA31Annotated By Reference To The Literature 1oe8
鎖名残基詳細
CTYR9

CSA41Annotated By Reference To The Literature 1oe8
鎖名残基詳細
DTYR9