1A3F
PHOSPHOLIPASE A2 (PLA2) FROM NAJA NAJA VENOM
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004623 | molecular_function | phospholipase A2 activity |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0005543 | molecular_function | phospholipid binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006644 | biological_process | phospholipid metabolic process |
| A | 0016042 | biological_process | lipid catabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047498 | molecular_function | calcium-dependent phospholipase A2 activity |
| A | 0050482 | biological_process | arachidonic acid secretion |
| B | 0004623 | molecular_function | phospholipase A2 activity |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0005543 | molecular_function | phospholipid binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0006644 | biological_process | phospholipid metabolic process |
| B | 0016042 | biological_process | lipid catabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0047498 | molecular_function | calcium-dependent phospholipase A2 activity |
| B | 0050482 | biological_process | arachidonic acid secretion |
| C | 0004623 | molecular_function | phospholipase A2 activity |
| C | 0005509 | molecular_function | calcium ion binding |
| C | 0005543 | molecular_function | phospholipid binding |
| C | 0005576 | cellular_component | extracellular region |
| C | 0006644 | biological_process | phospholipid metabolic process |
| C | 0016042 | biological_process | lipid catabolic process |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0047498 | molecular_function | calcium-dependent phospholipase A2 activity |
| C | 0050482 | biological_process | arachidonic acid secretion |
Functional Information from PDB Data
| site_id | CAA |
| Number of Residues | 6 |
| Details | CA BINDING SITE. |
| Chain | Residue |
| A | TYR27 |
| A | CYS28 |
| A | GLY29 |
| A | ARG30 |
| A | GLY31 |
| A | ASP48 |
| site_id | CAB |
| Number of Residues | 6 |
| Details | CA BINDING SITE. |
| Chain | Residue |
| B | ARG30 |
| B | GLY31 |
| B | ASP48 |
| B | TYR27 |
| B | CYS28 |
| B | GLY29 |
| site_id | CAC |
| Number of Residues | 6 |
| Details | CA BINDING SITE. |
| Chain | Residue |
| C | TYR27 |
| C | CYS28 |
| C | GLY29 |
| C | ARG30 |
| C | GLY31 |
| C | ASP48 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | ACT_SITE: ACT_SITE => ECO:0000305|PubMed:8419939 |
| Chain | Residue | Details |
| A | HIS47 | |
| A | ASP93 | |
| B | HIS47 | |
| B | ASP93 | |
| C | HIS47 | |
| C | ASP93 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:8419939, ECO:0007744|PDB:1PSH |
| Chain | Residue | Details |
| A | TYR27 | |
| C | GLY29 | |
| C | GLY31 | |
| C | ASP48 | |
| A | GLY29 | |
| A | GLY31 | |
| A | ASP48 | |
| B | TYR27 | |
| B | GLY29 | |
| B | GLY31 | |
| B | ASP48 | |
| C | TYR27 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1n29 |
| Chain | Residue | Details |
| A | HIS47 | |
| A | ASP93 | |
| A | GLY29 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1n29 |
| Chain | Residue | Details |
| B | HIS47 | |
| B | ASP93 | |
| B | GLY29 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1n29 |
| Chain | Residue | Details |
| C | HIS47 | |
| C | ASP93 | |
| C | GLY29 |
