5MMG
Crystal structure of CREBBP bromodomain complexed with UT07C
Experimental procedure
Experimental method | SINGLE WAVELENGTH |
Source type | SYNCHROTRON |
Source details | SLS BEAMLINE X06SA |
Synchrotron site | SLS |
Beamline | X06SA |
Temperature [K] | 100 |
Detector technology | PIXEL |
Collection date | 2016-09-26 |
Detector | DECTRIS EIGER X 16M |
Wavelength(s) | 0.99998 |
Spacegroup name | P 21 21 21 |
Unit cell lengths | 34.181, 49.299, 80.505 |
Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
Resolution | 40.252 - 1.230 |
R-factor | 0.1574 |
Rwork | 0.157 |
R-free | 0.16300 |
Structure solution method | MOLECULAR REPLACEMENT |
Starting model (for MR) | 3dwy |
RMSD bond length | 0.005 |
RMSD bond angle | 0.872 |
Data reduction software | XDS |
Data scaling software | XDS |
Phasing software | PHASER |
Refinement software | PHENIX ((1.11.1_2575: ???)) |
Data quality characteristics
Overall | |
Low resolution limit [Å] | 42.040 |
High resolution limit [Å] | 1.230 |
Rmerge | 0.163 |
Number of reflections | 39623 |
<I/σ(I)> | 28.2 |
Completeness [%] | 98.4 |
Redundancy | 5.6 |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 | VAPOR DIFFUSION, HANGING DROP | 277 | 0.15 M KSCN, 10% Ethylene Glycol, 20% PEG3350 |