9ORW
 
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9ORX
 | | X-ray diffraction structure of lysozyme complexed with N,N',N"-triacetylchitotriose from a cocktail-soaked crystal | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Lysozyme C | | Authors: | Flowers, C.W, Vlahakis, N.W, Rodriguez, J.A. | | Deposit date: | 2025-05-23 | | Release date: | 2025-06-18 | | Last modified: | 2025-08-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Combining MicroED and native mass spectrometry for structural discovery of enzyme-small molecule complexes.
Proc.Natl.Acad.Sci.USA, 122, 2025
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9ORY
 | | X-ray diffraction structure of lysozyme soaked with N,N',N"-triacetylchitotriose | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Lysozyme C | | Authors: | Flowers, C.W, Vlahakis, N.W, Rodriguez, J.A. | | Deposit date: | 2025-05-23 | | Release date: | 2025-06-18 | | Last modified: | 2025-08-13 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Combining MicroED and native mass spectrometry for structural discovery of enzyme-small molecule complexes.
Proc.Natl.Acad.Sci.USA, 122, 2025
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9ORZ
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9OS0
 | | MicroED structure of lysozyme complexed with N,N',N"-triacetylchitotriose from cocktail-soaked crystals | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lysozyme C, SODIUM ION | | Authors: | Vlahakis, N.W, Flowers, C.W, Rodriguez, J.A. | | Deposit date: | 2025-05-23 | | Release date: | 2025-06-18 | | Last modified: | 2025-08-13 | | Method: | ELECTRON CRYSTALLOGRAPHY (2.4 Å) | | Cite: | Combining MicroED and native mass spectrometry for structural discovery of enzyme-small molecule complexes.
Proc.Natl.Acad.Sci.USA, 122, 2025
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9OS1
 | | MicroED structure of lysozyme co-crystallized with N,N',N"-triacetylchitotriose | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lysozyme C, SODIUM ION | | Authors: | Vlahakis, N.W, Flowers, C.W, Rodriguez, J.A. | | Deposit date: | 2025-05-23 | | Release date: | 2025-06-18 | | Last modified: | 2025-08-13 | | Method: | ELECTRON CRYSTALLOGRAPHY (2.3 Å) | | Cite: | Combining MicroED and native mass spectrometry for structural discovery of enzyme-small molecule complexes.
Proc.Natl.Acad.Sci.USA, 122, 2025
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9OS8
 | | MicroED structure of lysozyme soaked with N,N',N"-triacetylchitotriose | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lysozyme C | | Authors: | Vlahakis, N.W, Flowers, C.W, Rodriguez, J.A. | | Deposit date: | 2025-05-23 | | Release date: | 2025-06-18 | | Last modified: | 2025-08-13 | | Method: | ELECTRON CRYSTALLOGRAPHY (2.3 Å) | | Cite: | Combining MicroED and native mass spectrometry for structural discovery of enzyme-small molecule complexes.
Proc.Natl.Acad.Sci.USA, 122, 2025
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9OYO
 | | Structure of R15L D10-NT amyloid fibrils | | Descriptor: | Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial | | Authors: | Lv, G, Eliezer, D. | | Deposit date: | 2025-06-04 | | Release date: | 2025-07-30 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (3.15 Å) | | Cite: | Amyloid fibril structures link CHCHD10 and CHCHD2 to neurodegeneration.
Nat Commun, 16, 2025
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9OYQ
 | | Structure of D10-NT amyloid fibrils | | Descriptor: | Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial | | Authors: | Lv, G, Eliezer, D. | | Deposit date: | 2025-06-04 | | Release date: | 2025-07-30 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Amyloid fibril structures link CHCHD10 and CHCHD2 to neurodegeneration.
Nat Commun, 16, 2025
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9OYR
 | | Structure of D2-NT amyloid fibrils | | Descriptor: | Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 | | Authors: | Lv, G, Eliezer, D. | | Deposit date: | 2025-06-04 | | Release date: | 2025-07-30 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (2.03 Å) | | Cite: | Amyloid fibril structures link CHCHD10 and CHCHD2 to neurodegeneration.
Nat Commun, 16, 2025
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9OYS
 | | Structure of S59L D10-NT amyloid fibrils | | Descriptor: | Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial | | Authors: | Lv, G, Eliezer, D. | | Deposit date: | 2025-06-04 | | Release date: | 2025-07-30 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (3.06 Å) | | Cite: | Amyloid fibril structures link CHCHD10 and CHCHD2 to neurodegeneration.
Nat Commun, 16, 2025
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9OYT
 | | Structure of T61I D2-NT amyloid fibrils | | Descriptor: | Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 | | Authors: | Lv, G, Eliezer, D. | | Deposit date: | 2025-06-04 | | Release date: | 2025-07-30 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Amyloid fibril structures link CHCHD10 and CHCHD2 to neurodegeneration.
Nat Commun, 16, 2025
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9OYW
 | | Structure of D10-NT amyloid fibrils | | Descriptor: | Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial | | Authors: | Lv, G, Eliezer, D. | | Deposit date: | 2025-06-04 | | Release date: | 2025-07-30 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (2.63 Å) | | Cite: | Amyloid fibril structures link CHCHD10 and CHCHD2 to neurodegeneration.
Nat Commun, 16, 2025
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9PDD
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9QDH
 | | Crystal structure of IgA protease (323-878) from Thomasclavelia ramosa | | Descriptor: | DI(HYDROXYETHYL)ETHER, IgA protease, ZINC ION | | Authors: | Marquez-Monino, M.A, Martinez Gascuena, A, Aguillo-Urarte, M, Manzanares-Gomez, A, Trastoy, B. | | Deposit date: | 2025-03-06 | | Release date: | 2025-07-16 | | Last modified: | 2025-08-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Molecular basis of Fab-dependent IgA antibody recognition by gut-bacterial metallopeptidases.
Embo J., 2025
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9QDI
 | | Crystal structure of BF3526 peptidase from Bacteroides fragilis in complex with a peptide | | Descriptor: | 1,2-ETHANEDIOL, 1,4-BUTANEDIOL, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Martinez Gascuena, A, Marquez-Monino, M.A, Manzanares-Gomez, A, Aguillo-Urarte, M, Trastoy, B. | | Deposit date: | 2025-03-06 | | Release date: | 2025-07-16 | | Last modified: | 2025-08-13 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Molecular basis of Fab-dependent IgA antibody recognition by gut-bacterial metallopeptidases.
Embo J., 2025
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9QDT
 | | Cytochrome c peroxidase YhjA | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Einsle, O, Wuest, A. | | Deposit date: | 2025-03-06 | | Release date: | 2025-07-30 | | Last modified: | 2025-08-13 | | Method: | X-RAY DIFFRACTION (2.572 Å) | | Cite: | Escherichia coli Triheme Enzyme YhjA: Structure and Reactivity.
Biochemistry, 64, 2025
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9QWP
 | | Structure of the human RalGAP2 complex | | Descriptor: | Ral GTPase-activating protein subunit alpha-2, Ral GTPase-activating protein subunit beta | | Authors: | Rasche, R, Klink, B.U, Gatsogiannis, C, Kuemmel, D. | | Deposit date: | 2025-04-15 | | Release date: | 2025-07-16 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structure and mechanism of the RalGAP tumor suppressor complex.
Nat Commun, 16, 2025
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9R0Q
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9RZF
 | | Structure of in-vivo formed alpha-synuclein fibrils purified from a M83+/- mouse brain injected with recombinant 1B fibrils | | Descriptor: | Alpha-synuclein | | Authors: | van den Heuvel, L, Burger, D, Kashyrina, M, de La Seigliere, H, Lewis, A.J, De Nuccio, F, Mohammed, I, Verchere, J, Feuillie, C, Berbon, M, Arotcarena, M, Retailleau, A, Bezard, E, Canron, M, Meissner, W.G, Loquet, A, Bousset, L, Poujol, C, Nilsson, K.P.R, Laferriere, F, Baron, T, Lofrumento, D.D, De Giorgi, F, Stahlberg, H, Ichas, F. | | Deposit date: | 2025-07-15 | | Release date: | 2025-07-30 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Synthetic alpha-synuclein fibrils replicate in mice causing MSA neuropathology
To Be Published, 2024
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9UJ0
 | | Structure of Aegerolysin-L pore | | Descriptor: | Aeg-L | | Authors: | Gao, P, Zhao, C.Q. | | Deposit date: | 2025-04-16 | | Release date: | 2025-06-18 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (3.81 Å) | | Cite: | Epithelial cell membrane perforation induces allergic airway inflammation.
Nature, 2025
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9VQL
 | | Cryo-EM structure of the dimeric Elapor1 mutant | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Endosome/lysosome-associated apoptosis and autophagy regulator 1 | | Authors: | Ma, J, Zheng, S. | | Deposit date: | 2025-07-05 | | Release date: | 2025-07-23 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | ELAPOR1 is a copper-dependent tethering factor driving proacrosomal vesicle fusion during acrosome biogenesis.
Proc.Natl.Acad.Sci.USA, 122, 2025
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9VQM
 | | Cryo-EM structure of Elapor1WT in tetrameric form | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, ... | | Authors: | Ma, J, Zheng, S. | | Deposit date: | 2025-07-05 | | Release date: | 2025-07-23 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | ELAPOR1 is a copper-dependent tethering factor driving proacrosomal vesicle fusion during acrosome biogenesis.
Proc.Natl.Acad.Sci.USA, 122, 2025
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9VWT
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