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8ZBG
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BU of 8zbg by Molmil
Crystal structure of TEAD3 YAP binding domain with compound 15
Descriptor: (2~{R})-2-fluoranyl-1-[7-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1~{H}-isoquinolin-2-yl]propan-1-one, Transcriptional enhancer factor TEF-5
Authors:Yoo, Y, Kim, H.
Deposit date:2024-04-26
Release date:2025-04-16
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Pan-Transcriptional Enhanced Associated Domain Palmitoylation Pocket Covalent Inhibitor.
J.Med.Chem., 67, 2024
8ZBH
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BU of 8zbh by Molmil
Crystal structure of TEAD3 YAP binding domain with compound 3
Descriptor: 1-[7-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1~{H}-isoquinolin-2-yl]propan-1-one, Transcriptional enhancer factor TEF-5
Authors:Yoo, Y, Kim, H.
Deposit date:2024-04-26
Release date:2025-04-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Pan-Transcriptional Enhanced Associated Domain Palmitoylation Pocket Covalent Inhibitor.
J.Med.Chem., 67, 2024
8ZN5
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BU of 8zn5 by Molmil
Crystal Structure of Designed Clock Protein KaiC
Descriptor: ADENOSINE-5'-DIPHOSPHATE, KaiC, MAGNESIUM ION
Authors:Furuike, Y, Akiyama, S.
Deposit date:2024-05-26
Release date:2025-04-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal Structure of Designed Clock Protein KaiC
To Be Published
8ZN6
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BU of 8zn6 by Molmil
Crystal Structure of Designed Clock Protein KaiC
Descriptor: KaiC, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Furuike, Y, Akiyama, S.
Deposit date:2024-05-26
Release date:2025-04-16
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Crystal Structure of Designed Clock Protein KaiC
To Be Published
8ZN7
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BU of 8zn7 by Molmil
Crystal Structure of Designed Clock Protein KaiC
Descriptor: KaiC, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Furuike, Y, Akiyama, S.
Deposit date:2024-05-26
Release date:2025-04-16
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Crystal Structure of Designed Clock Protein KaiC
To Be Published
8ZP4
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BU of 8zp4 by Molmil
Cryo-EM structure of origin recognition complex (Orc1 to 5) with ARS1 DNA bound
Descriptor: DNA (31-MER), MAGNESIUM ION, Origin recognition complex subunit 1, ...
Authors:Lam, W.H, Yu, D, Dang, S, Zhai, Y.
Deposit date:2024-05-29
Release date:2025-04-16
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:DNA bending mediated by ORC is essential for replication licensing in budding yeast.
Proc.Natl.Acad.Sci.USA, 122, 2025
8ZP5
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BU of 8zp5 by Molmil
Cryo-EM structure of origin recognition complex (Orc5 basic patch mutations) with ARS1 DNA bound
Descriptor: DNA (34-MER), DNA (35-MER), MAGNESIUM ION, ...
Authors:Lam, W.H, Yu, D, Dang, S, Zhai, Y.
Deposit date:2024-05-29
Release date:2025-04-16
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:DNA bending mediated by ORC is essential for replication licensing in budding yeast.
Proc.Natl.Acad.Sci.USA, 122, 2025
8ZPK
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BU of 8zpk by Molmil
Cryo-EM structure of origin recognition complex (Orc6 with residues 1 to 270 deleted) with ARS1 DNA bound
Descriptor: DNA (38-MER), DNA (40-MER), MAGNESIUM ION, ...
Authors:Lam, W.H, Yu, D, Dang, S, Zhai, Y.
Deposit date:2024-05-30
Release date:2025-04-16
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:DNA bending mediated by ORC is essential for replication licensing in budding yeast.
Proc.Natl.Acad.Sci.USA, 122, 2025
8ZS0
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BU of 8zs0 by Molmil
Plasmodium falciparum Nucleoplasmin (PfNPM)
Descriptor: Nucleoplasmin-like domain-containing protein
Authors:Saharan, K, Vasudevan, D.
Deposit date:2024-06-05
Release date:2025-04-16
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structure-function studies of a nucleoplasmin isoform from Plasmodium falciparum.
J.Biol.Chem., 301, 2025
8ZU6
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BU of 8zu6 by Molmil
Solution NMR Structure of PACT D3 Homodimer
Descriptor: Interferon-inducible double-stranded RNA-dependent protein kinase activator A
Authors:Zhao, L, Ahmad, S, Hur, S, Chou, J.
Deposit date:2024-06-08
Release date:2025-04-16
Method:SOLUTION NMR
Cite:PACT prevents aberrant activation of PKR by endogenous dsRNA without sequestration.
Nat Commun, 16, 2025
8ZXM
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BU of 8zxm by Molmil
Cryo-EM structure of human GLUT9 bound to urate
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier family 2, facilitated glucose transporter member 9, ...
Authors:Matsushita, D, Lee, Y, Nishizawa, T.
Deposit date:2024-06-14
Release date:2025-04-16
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Structural basis of urate transport by glucose transporter 9.
Cell Rep, 44, 2025
8ZXN
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BU of 8zxn by Molmil
Cryo-EM structure of human GLUT9 apo state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier family 2, facilitated glucose transporter member 9
Authors:Matsushita, D, Lee, Y, Nishizawa, T.
Deposit date:2024-06-14
Release date:2025-04-16
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Structural basis of urate transport by glucose transporter 9.
Cell Rep, 44, 2025
8ZYU
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BU of 8zyu by Molmil
Cryo-EM structure of neurotensin receptor 1 in complex with beta-arrestin1 and SBI-553 (complex 1)
Descriptor: 2-[{2-(1-fluorocyclopropyl)-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl}(methyl)amino]ethan-1-ol, Beta-arrestin-1, Fab30 heavy chain, ...
Authors:Sun, D, Li, X, Yuan, Q, Yin, W, Xu, H.E, Tian, C.
Deposit date:2024-06-18
Release date:2025-04-16
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Molecular mechanism of the arrestin-biased agonism of neurotensin receptor 1 by an intracellular allosteric modulator.
Cell Res., 35, 2025
9B3E
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BU of 9b3e by Molmil
Crystal structure of a Slam-dependent surface lipoprotein, PmSLP, in Pasteurella multocida
Descriptor: SELENIUM ATOM, surface lipoprotein, PmSLP-1
Authors:Lai, C.H.R, Shah, M, Nguyen, Q.H, Moraes, T.F.
Deposit date:2024-03-19
Release date:2025-04-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Slam-dependent surface lipoprotein in Pasteurella multocida binds complement factor I and promotes immune evasion
To Be Published
9B4X
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BU of 9b4x by Molmil
SARS CoV-2 full-length spike protein with Lys1269Ala and His1271Ala substitutions in the coatomer binding motif, 1RBD-up conformation (SPIKE-AXA)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Singh, S, Hasan, S.S.
Deposit date:2024-03-21
Release date:2025-04-16
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Cryo-EM structure of SARS CoV-2 full-length spike with Lys1269Ala and His1271Ala substitutions in the coatomer binding motif, 1RBD-up conformation
To Be Published
9B6O
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BU of 9b6o by Molmil
Fab1-2 in complex with the capsid of Adeno-associated virus type 9
Descriptor: Capsid protein VP1, Fab1-2 heavy chain, Fab1-2 light chain
Authors:Mietzsch, M, McKenna, R.
Deposit date:2024-03-25
Release date:2025-04-16
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Structural characterization of antibody-responses from Zolgensma treatment guides the design of a capsid suitable for redosing
Nat Commun, 2025
9B6P
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BU of 9b6p by Molmil
Fab1-3 in complex with the capsid of Adeno-associated virus type 9
Descriptor: Capsid protein VP1, Fab1-3 heavy chain, Fab1-3 light chain
Authors:Mietzsch, M, McKenna, R.
Deposit date:2024-03-25
Release date:2025-04-16
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Structural characterization of antibody-responses from Zolgensma treatment guides the design of a capsid suitable for redosing
Nat Commun, 2025
9B6Q
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BU of 9b6q by Molmil
Fab1-4 in complex with the capsid of Adeno-associated virus type 9
Descriptor: Capsid protein VP1, Fab1-4 heavy chain, Fab1-4 light chain
Authors:Mietzsch, M, McKenna, R.
Deposit date:2024-03-25
Release date:2025-04-16
Method:ELECTRON MICROSCOPY (2.77 Å)
Cite:Structural characterization of antibody-responses from Zolgensma treatment guides the design of a capsid suitable for redosing
Nat Commun, 2025
9B6R
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BU of 9b6r by Molmil
Fab1-5 in complex with the capsid of Adeno-associated virus type 9
Descriptor: Capsid protein VP1, Fab1-5 heavy chain, Fab1-5 light chain
Authors:Mietzsch, M, McKenna, R.
Deposit date:2024-03-25
Release date:2025-04-16
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Structural characterization of antibody-responses from Zolgensma treatment guides the design of a capsid suitable for redosing
Nat Commun, 2025
9B6S
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BU of 9b6s by Molmil
Fab1-6 in complex with the capsid of Adeno-associated virus type 9
Descriptor: Capsid protein VP1, Fab1-6 heavy chain, Fab1-6 light chain
Authors:Mietzsch, M, McKenna, R.
Deposit date:2024-03-25
Release date:2025-04-16
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Structural characterization of antibody-responses from Zolgensma treatment guides the design of a capsid suitable for redosing
Nat Commun, 2025
9B6T
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BU of 9b6t by Molmil
Fab1-7 in complex with the capsid of Adeno-associated virus type 9
Descriptor: Capsid protein VP1, Fab1-7 heavy chain, Fab1-7 light chain
Authors:Mietzsch, M, McKenna, R.
Deposit date:2024-03-25
Release date:2025-04-16
Method:ELECTRON MICROSCOPY (2.54 Å)
Cite:Structural characterization of antibody-responses from Zolgensma treatment guides the design of a capsid suitable for redosing
Nat Commun, 2025
9B7J
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BU of 9b7j by Molmil
Cryo-EM structure of human dynactin complex bound to Chlamydia effector Dre1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ...
Authors:Pawar, K.I, Verba, K.A.
Deposit date:2024-03-27
Release date:2025-04-16
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:The Chlamydia effector Dre1 binds dynactin to reposition host organelles during infection.
Cell Rep, 44, 2025
9B7K
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BU of 9b7k by Molmil
Fab2-1 in complex with the capsid of Adeno-associated virus type 9
Descriptor: Capsid protein VP1, Fab2-1 heavy chain, Fab2-1 light chain
Authors:Mietzsch, M, McKenna, R.
Deposit date:2024-03-27
Release date:2025-04-16
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:Structural characterization of antibody-responses from Zolgensma treatment guides the design of a capsid suitable for redosing
Nat Commun, 2025
9B7L
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BU of 9b7l by Molmil
Fab2-2 in complex with the capsid of Adeno-associated virus type 9
Descriptor: Capsid protein VP1, Fab2-2 heavy chain, Fab2-2 light chain
Authors:Mietzsch, M, McKenna, R.
Deposit date:2024-03-27
Release date:2025-04-16
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:Structural characterization of antibody-responses from Zolgensma treatment guides the design of a capsid suitable for redosing
Nat Commun, 2025
9B7M
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BU of 9b7m by Molmil
Fab2-3 in complex with the capsid of Adeno-associated virus type 9
Descriptor: CALCIUM ION, Capsid protein VP1, Fab2-3 heavy chain, ...
Authors:Mietzsch, M, McKenna, R.
Deposit date:2024-03-27
Release date:2025-04-16
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:Structural characterization of antibody-responses from Zolgensma treatment guides the design of a capsid suitable for redosing
Nat Commun

234785

數據於2025-04-16公開中

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