9NIV
 
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9NJ8
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9NNA
 | | Crystal structure of CYP46A1 with [(1R,5S)-3-oxa-8-azabicyclo[3.2.1]octan-8-yl][(4R,8M)-8-(1,3-oxazol-5-yl)-6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]methanone (compound 3k) | | Descriptor: | Cholesterol 24-hydroxylase, PROTOPORPHYRIN IX CONTAINING FE, [(1R,5S)-3-oxa-8-azabicyclo[3.2.1]octan-8-yl][(4R,8M)-8-(1,3-oxazol-5-yl)-6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]methanone | | Authors: | Yano, J, Skene, R.J. | | Deposit date: | 2025-03-05 | | Release date: | 2025-07-02 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Structure-based design of a novel series of cholesterol 24-hydroxylase (CH24H) inhibitors bearing 1,3-oxazole as a heme-iron binding group.
Bioorg.Med.Chem., 128, 2025
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9NND
 | | Structure of the HERV-K (HML-2) spike complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Shaked, R, Katz, M, Diskin, R. | | Deposit date: | 2025-03-05 | | Release date: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (2.13 Å) | | Cite: | The prefusion structure of the HERV-K spike complex
To Be Published
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9NNE
 | | Crystal structure of CYP46A1 with (morpholin-4-yl)[(4R,8M)-8-(1,3-oxazol-5-yl)-6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]methanone (compound 2h) | | Descriptor: | (morpholin-4-yl)[(4R,8M)-8-(1,3-oxazol-5-yl)-6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]methanone, Cholesterol 24-hydroxylase, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Yano, J, Skene, R.J. | | Deposit date: | 2025-03-05 | | Release date: | 2025-07-02 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structure-based design of a novel series of cholesterol 24-hydroxylase (CH24H) inhibitors bearing 1,3-oxazole as a heme-iron binding group.
Bioorg.Med.Chem., 128, 2025
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9NNI
 | | Crystal structure of CYP46A1 with cyclopropyl[(4M)-4-(1,3-oxazol-5-yl)-6-(trifluoromethyl)-1H-indol-1-yl]methanone (compound 2b) | | Descriptor: | 1,2-ETHANEDIOL, Cholesterol 24-hydroxylase, PROTOPORPHYRIN IX CONTAINING FE, ... | | Authors: | Yano, J, Skene, R.J. | | Deposit date: | 2025-03-05 | | Release date: | 2025-07-02 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure-based design of a novel series of cholesterol 24-hydroxylase (CH24H) inhibitors bearing 1,3-oxazole as a heme-iron binding group.
Bioorg.Med.Chem., 128, 2025
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9NOF
 | | [7,7,6-1] Shifted tensegrity triangle with an (arm,center,arm) distribution of (7,7,6) base pairs and 1 nt sticky ends, with hexagonal symmetry | | Descriptor: | DNA (5'-D(*CP*TP*GP*AP*TP*GP*TP*GP*GP*CP*TP*GP*CP*T)-3'), DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*A)-3'), DNA (5'-D(P*AP*CP*AP*CP*CP*GP*T)-3'), ... | | Authors: | Abi Rizk, J, Horvath, A, Vecchioni, S, Woloszyn, K, Ohayon, Y.P, Sha, R. | | Deposit date: | 2025-03-10 | | Release date: | 2025-07-02 | | Method: | X-RAY DIFFRACTION (4.08 Å) | | Cite: | Shifted tensegrity triangles
To Be Published
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9NOG
 | | [0,6,13-2] Shifted DNA assembly with an aspect ratio of (0,6,13) base pairs and 2 nt sticky ends containing a semi-junction | | Descriptor: | DNA (5'-D(*GP*AP*TP*GP*CP*GP*AP*GP*GP*TP*GP*CP*TP*GP*T)-3'), DNA (5'-D(*TP*CP*TP*GP*TP*CP*GP*GP*AP*CP*AP*GP*CP*AP*CP*CP*TP*CP*GP*CP*A)-3'), DNA (5'-D(P*CP*CP*G)-3') | | Authors: | Horvath, A, Woloszyn, K, Vecchioni, S, Ohayon, Y.P, Sha, R. | | Deposit date: | 2025-03-10 | | Release date: | 2025-07-02 | | Method: | X-RAY DIFFRACTION (4.89 Å) | | Cite: | shifted tensegrity triangles
To Be Published
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9NR6
 | | The structure of Noelin 1 with cerebellar GluA1/A4-ATD | | Descriptor: | 11B8 scFv, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Fang, C.F, Gouaux, E. | | Deposit date: | 2025-03-14 | | Release date: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.26 Å) | | Cite: | Gating and noelin clustering of native Ca2+-permeable AMPA receptors
Nature, 2025
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9NR7
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9NR8
 | | The structure of cerebellar GluA1/A4 ATD | | Descriptor: | 11B8 scFv, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Fang, C.F, Gouaux, E. | | Deposit date: | 2025-03-14 | | Release date: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.53 Å) | | Cite: | Gating and noelin clustering of native Ca2+-permeable AMPA receptors
Nature, 2025
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9NR9
 | | The structure of GluA1/A4 LBD-TMD with 2 TARPs | | Descriptor: | Glutamate receptor 1, Isoform 2 of Glutamate receptor 4, Voltage-dependent calcium channel gamma-2 subunit, ... | | Authors: | Fang, C.F, Gouaux, E. | | Deposit date: | 2025-03-14 | | Release date: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (4.22 Å) | | Cite: | Gating and noelin clustering of native Ca2+-permeable AMPA receptors
Nature, 2025
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9NRA
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9NV3
 | | Hybrid model of a complex of BREX proteins BrxB and PglZ from Salmonella typhimurium | | Descriptor: | DUF1788 domain-containing protein, PglZ domain-containing protein | | Authors: | Doyle, L.A, Stoddard, B, Blower, T.R, Kaiser, B. | | Deposit date: | 2025-03-20 | | Release date: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (4.45 Å) | | Cite: | PglZ from Type I BREX phage defence systems is a metal-dependent nuclease that forms a sub-complex with BrxB
Nucleic Acids Res., 53, 2025
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9NYO
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9O0D
 | | crystal structure of rSAMD9 tRNase domain | | Descriptor: | rSAMD9 | | Authors: | Deng, J.P. | | Deposit date: | 2025-04-02 | | Release date: | 2025-07-02 | | Method: | X-RAY DIFFRACTION (2.391 Å) | | Cite: | Structural and Functional Studies of Rabbit SAMD9 Reveal a Distinct tRNase Module That Underlies the Antiviral Activity
To Be Published
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9O4A
 | | Ec83 Retron PtuAB mutant complex | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Retron Ec83 probable ATPase, Retron Ec83 putative HNH endonuclease, ... | | Authors: | Wang, C, Rish, A, Fu, T.M. | | Deposit date: | 2025-04-08 | | Release date: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Disassembly activates Retron-Septu for antiphage defense.
Science, 2025
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9OHS
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9OTM
 | | Human glutamine synthetase filament under turnover conditions | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GLUTAMINE, Glutamine synthetase, ... | | Authors: | Greene, E.R, Muniz, R.S, Kollman, J.M, Fraser, J.S. | | Deposit date: | 2025-05-27 | | Release date: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (2.19 Å) | | Cite: | Product-stabilized filamentation by human glutamine synthetase allosterically tunes metabolic activity
To Be Published
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9OTN
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9OTO
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9OTP
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9OTQ
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9OU1
 | | Crystal structure of maize AKR4C13 in P21 space group | | Descriptor: | 1,2-ETHANEDIOL, Aldose reductase, AKR4C13, ... | | Authors: | Santos, M.L, Giuseppe, P.O, Kiyota, E, Schmelz, E.A, Yunes, J.A, Koch, K.E, Murakami, M.T, Aparicio, R, Sousa, S.M. | | Deposit date: | 2025-05-28 | | Release date: | 2025-07-02 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Functional Genomics and Structural Insights into Maize Aldo-Keto Reductase-4 Family: Stress Metabolism and Substrate Specificity in Embryos.
J.Biol.Chem., 2025
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9P6P
 | | Crystal Structure of the SARS-CoV-2 2'-O-Methyltransferase with (m7GpppA)pUpU (Cap-0) and S-Adenosyl-L-homocysteine (SAH). | | Descriptor: | 2'-O-methyltransferase, 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... | | Authors: | Minasov, G, Shuvalova, L, Maltseva, N, Kim, Y, Kiryukhina, O, Joachimiak, A, Satchell, K.J.F, Center for Structural Biology of Infectious Diseases (CSBID) | | Deposit date: | 2025-06-19 | | Release date: | 2025-07-02 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Crystal Structure of the SARS-CoV-2 2'-O-Methyltransferase with (m7GpppA)pUpU (Cap-0) and S-Adenosyl-L-homocysteine (SAH).
To Be Published
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