9PB1
 
 | | Human ClpP initial assembly | | Descriptor: | ATP-dependent Clp protease proteolytic subunit, mitochondrial | | Authors: | Chen, W.C. | | Deposit date: | 2025-06-26 | | Release date: | 2025-11-19 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Assembly and proteolytic activation human ClpXP defined by cryo-EM
To Be Published
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9PDI
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9PDL
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9PDN
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9PF1
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9PHR
 | | BTB modified at C151 with monobimane | | Descriptor: | 3-(bromomethyl)-2,5,6-trimethyl-1H,7H-pyrazolo[1,2-a]pyrazole-1,7-dione, Kelch-like ECH-associated protein 1 | | Authors: | Ragwan, E.R, Kung, Y, Eggler, A.L. | | Deposit date: | 2025-07-09 | | Release date: | 2025-11-19 | | Method: | X-RAY DIFFRACTION (1.801 Å) | | Cite: | KEAP1 C151 active site catalysis drives electrophilic signaling to upregulate cytoprotective enzyme expression.
Redox Biol, 88, 2025
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9PW4
 | | Structure of V30V4 in complex with SARS-CoV-2 spike | | Descriptor: | SP1-77 FAB HEAVY CHAIN, SP1-77 FAB LIGHT CHAIN, Spike protein S1, ... | | Authors: | Wang, Y.J, Kibria, G, Wesemann, D, Chen, B. | | Deposit date: | 2025-08-04 | | Release date: | 2025-11-19 | | Method: | ELECTRON MICROSCOPY (2.85 Å) | | Cite: | Affinity Maturation and light-Chain-Mediated Paratope Diversification Anticipates Viral Evolution
To Be Published
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9QD0
 | | Structure of Beilong paramyxovirus receptor binding protein | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Attachment glycoprotein, alpha-D-mannopyranose, ... | | Authors: | Stelfox, A.J, Bowden, T.A. | | Deposit date: | 2025-03-05 | | Release date: | 2025-11-19 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structure of the Jeilongvirus Receptor Binding Receptor Protein Provides a Molecular Basis for Elongation of the Paramyxoviral C-terminus
To Be Published
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9QD1
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9QM6
 | | Crystal structure of highly stable methionine gamma-lyase from Thermobrachium celere in complex with PLP and norleucine | | Descriptor: | 1,2-ETHANEDIOL, L-methionine gamma-lyase, NORLEUCINE | | Authors: | Kopecny, D, Ferchaud, N, Briozzo, P. | | Deposit date: | 2025-03-21 | | Release date: | 2025-11-19 | | Method: | X-RAY DIFFRACTION (2.607 Å) | | Cite: | The methioninase from the alkalithermophile Thermobrachium celere possesses suitable properties for treatment of cancer.
Int.J.Biol.Macromol., 330, 2025
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9QOW
 | | APH(2'')-IVa with an inhibitor | | Descriptor: | 2-[4-(5-chloranyl-1~{H}-pyrrolo[2,3-b]pyridin-4-yl)-1,2,3-triazol-1-yl]ethanamide, APH(2'')-Id, DIMETHYL SULFOXIDE | | Authors: | Guichou, J.F, Gelin, M, Tomaszczyk, M, Kowalewski, J, Lionne, C. | | Deposit date: | 2025-03-26 | | Release date: | 2025-11-19 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | APH(2'')-IVa with an inhibitor
To Be Published
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9QPF
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9QPU
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9QT3
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9QUC
 | | Metal-free de novo protein scaffold TFD-EH | | Descriptor: | 1,2-ETHANEDIOL, CITRIC ACID, TFD-EH | | Authors: | Wagner Egea, P, Delhommel, F, Mustafa, G, Leiss-Maier, F, Klimper, L, Badmann, T, Heider, A, Wille, I.C, Groll, M, Sattler, M, Zeymer, C. | | Deposit date: | 2025-04-10 | | Release date: | 2025-11-19 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Modular protein scaffold architecture and AI-guided sequence optimization facilitate de novo metalloenzyme engineering.
Structure, 2025
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9QUD
 | | Cu(II)-bound de novo protein scaffold TFD-EH | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, COPPER (II) ION, ... | | Authors: | Wagner Egea, P, Delhommel, F, Mustafa, G, Leiss-Maier, F, Klimper, L, Badmann, T, Heider, A, Wille, I.C, Groll, M, Sattler, M, Zeymer, C. | | Deposit date: | 2025-04-10 | | Release date: | 2025-11-19 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Modular protein scaffold architecture and AI-guided sequence optimization facilitate de novo metalloenzyme engineering.
Structure, 2025
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9QUI
 | | Ni(II)-bound de novo protein scaffold TFD-EH | | Descriptor: | GLYCEROL, IMIDAZOLE, NICKEL (II) ION, ... | | Authors: | Wagner Egea, P, Delhommel, F, Mustafa, G, Leiss-Maier, F, Klimper, L, Badmann, T, Heider, A, Wille, I.C, Groll, M, Sattler, M, Zeymer, C. | | Deposit date: | 2025-04-10 | | Release date: | 2025-11-19 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Modular protein scaffold architecture and AI-guided sequence optimization facilitate de novo metalloenzyme engineering.
Structure, 2025
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9QUL
 | | Zn(II)-bound de novo protein scaffold TFD-EH T87E | | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, IMIDAZOLE, ... | | Authors: | Wagner Egea, P, Delhommel, F, Mustafa, G, Leiss-Maier, F, Klimper, L, Badmann, T, Heider, A, Wille, I.C, Groll, M, Sattler, M, Zeymer, C. | | Deposit date: | 2025-04-10 | | Release date: | 2025-11-19 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Modular protein scaffold architecture and AI-guided sequence optimization facilitate de novo metalloenzyme engineering.
Structure, 2025
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9QUO
 | | Co(II)-bound de novo protein scaffold TFD-EH T87E | | Descriptor: | COBALT (II) ION, GLYCEROL, IMIDAZOLE, ... | | Authors: | Wagner Egea, P, Delhommel, F, Mustafa, G, Leiss-Maier, F, Klimper, L, Badmann, T, Heider, A, Wille, I.C, Groll, M, Sattler, M, Zeymer, C. | | Deposit date: | 2025-04-10 | | Release date: | 2025-11-19 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Modular protein scaffold architecture and AI-guided sequence optimization facilitate de novo metalloenzyme engineering.
Structure, 2025
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9QUP
 | | Tb(III)-bound de novo protein scaffold TFD-EE MPNN | | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, SODIUM ION, ... | | Authors: | Wagner Egea, P, Delhommel, F, Mustafa, G, Leiss-Maier, F, Klimper, L, Badmann, T, Heider, A, Wille, I.C, Groll, M, Sattler, M, Zeymer, C. | | Deposit date: | 2025-04-10 | | Release date: | 2025-11-19 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Modular protein scaffold architecture and AI-guided sequence optimization facilitate de novo metalloenzyme engineering.
Structure, 2025
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9R6N
 | | Crystal structure of ALDH1A2 in complex with KyA33 | | Descriptor: | 1,2-ETHANEDIOL, 3-ethyl-~{N}-(8-methyl-2-oxidanylidene-3,4-dihydro-1~{H}-quinolin-6-yl)pyridine-4-carboxamide, Retinal dehydrogenase 2 | | Authors: | Fang, C, Esposito, M, Huang, J, Kang, Y. | | Deposit date: | 2025-05-13 | | Release date: | 2025-11-19 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Manuscript in preparation
To Be Published
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9RAS
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9RAV
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9RC3
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9RC5
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