7P5Z
| Structure of a DNA-loaded MCM double hexamer engaged with the Dbf4-dependent kinase | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 7, ... | 著者 | Greiwe, J.F, Miller, T.C.R, Martino, F, Costa, A. | 登録日 | 2021-07-15 | 公開日 | 2022-02-02 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural mechanism for the selective phosphorylation of DNA-loaded MCM double hexamers by the Dbf4-dependent kinase. Nat.Struct.Mol.Biol., 29, 2022
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7P6F
| 1.93 A resolution X-ray crystal structure of the transcriptional regulator SrnR from Streptomyces griseus | 分子名称: | ACETATE ION, SODIUM ION, Transcriptional regulator SrnR | 著者 | Mazzei, L, Ciurli, S. | 登録日 | 2021-07-16 | 公開日 | 2022-05-25 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Structure, dynamics, and function of SrnR, a transcription factor for nickel-dependent gene expression. Metallomics, 13, 2021
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7P6V
| N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH compound 3ag | 分子名称: | Bromodomain-containing protein 4, ethyl 2-(2-(4-azido-N-((2-(1,5-dimethyl-6-oxo-1,6-dihydropyridin-3-yl)-1-((tetrahydro-2H-pyran-4-yl)methyl)-1H-benzo[d]imidazol-6-yl)methyl)-2,3,5,6-tetrafluorobenzamido)acetamido)acetate | 著者 | Chung, C. | 登録日 | 2021-07-18 | 公開日 | 2021-10-06 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.17 Å) | 主引用文献 | One-Step Synthesis of Photoaffinity Probes for Live-Cell MS-Based Proteomics. Chemistry, 27, 2021
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7P6W
| N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH compound 3bg | 分子名称: | Bromodomain-containing protein 4, ethyl 2-(2-(4-azido-N-((2-(1,5-dimethyl-6-oxo-1,6-dihydropyridin-3-yl)-1-((tetrahydro-2H-pyran-4-yl)methyl)-1H-benzo[d]imidazol-6-yl)methyl)benzamido)acetamido)acetate | 著者 | Chung, C. | 登録日 | 2021-07-18 | 公開日 | 2021-10-06 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | 主引用文献 | One-Step Synthesis of Photoaffinity Probes for Live-Cell MS-Based Proteomics. Chemistry, 27, 2021
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7P6Y
| N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH compound 5ef | 分子名称: | 4-benzoyl-N-(2-(2-(2-((2-(1,5-dimethyl-6-oxo-1,6-dihydropyridin-3-yl)-1-((tetrahydro-2H-pyran-4-yl)methyl)-1H-benzo[d]imidazol-6-yl)(methyl)amino)ethoxy)ethoxy)ethyl)-N-(2-oxo-2-((2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl)amino)ethyl)benzamide, Bromodomain-containing protein 4 | 著者 | Chung, C. | 登録日 | 2021-07-18 | 公開日 | 2021-10-06 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.881 Å) | 主引用文献 | One-Step Synthesis of Photoaffinity Probes for Live-Cell MS-Based Proteomics. Chemistry, 27, 2021
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7P6Z
| Mycoplasma pneumoniae 70S ribosome in untreated cells | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Xue, L, Lenz, S, Rappsilber, J, Mahamid, J. | 登録日 | 2021-07-18 | 公開日 | 2022-05-25 | 最終更新日 | 2022-10-19 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Visualizing translation dynamics at atomic detail inside a bacterial cell. Nature, 610, 2022
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7P75
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7P7I
| Native structure of N-acetylglucosamine kinase from Plesiomonas shigelloides | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | 著者 | Roy, S, Isupov, M.N, Harmer, N.J, Ames, J.R. | 登録日 | 2021-07-19 | 公開日 | 2022-07-27 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases J.Biol.Chem., 2022
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7P7N
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7P7O
| X-RAY CRYSTAL STRUCTURE OF SPOROSARCINA PASTEURII UREASE INHIBITED BY THE GOLD(I)-DIPHOSPHINE COMPOUND Au(PEt3)2Cl DETERMINED AT 1.87 ANGSTROMS | 分子名称: | 1,2-ETHANEDIOL, NICKEL (II) ION, OXYGEN ATOM, ... | 著者 | Mazzei, L, Ciurli, S, Cianci, M, Messori, L, Massai, L. | 登録日 | 2021-07-20 | 公開日 | 2022-06-01 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Medicinal Au(I) compounds targeting urease as prospective antimicrobial agents: unveiling the structural basis for enzyme inhibition. Dalton Trans, 50, 2021
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7P7Q
| E. faecalis 70S ribosome bound by PoxtA-EQ2, high-resolution combined volume | 分子名称: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | 著者 | Crowe-McAuliffe, C, Wilson, D.N. | 登録日 | 2021-07-20 | 公開日 | 2022-02-23 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics. Nat Commun, 13, 2022
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7P7R
| PoxtA-EQ2 antibiotic resistance ABCF bound to E. faecalis 70S ribosome, state I | 分子名称: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | 著者 | Crowe-McAuliffe, C, Wilson, D.N. | 登録日 | 2021-07-20 | 公開日 | 2022-03-23 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics. Nat Commun, 13, 2022
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7P7S
| PoxtA-EQ2 antibiotic resistance ABCF bound to E. faecalis 70S ribosome, state II | 分子名称: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | 著者 | Crowe-McAuliffe, C, Wilson, D.N. | 登録日 | 2021-07-20 | 公開日 | 2022-02-23 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics. Nat Commun, 13, 2022
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7P7T
| PoxtA-EQ2 antibiotic resistance ABCF bound to E. faecalis 70S ribosome, state III | 分子名称: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | 著者 | Crowe-McAuliffe, C, Wilson, D.N. | 登録日 | 2021-07-20 | 公開日 | 2022-02-23 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics. Nat Commun, 13, 2022
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7P7U
| E. faecalis 70S ribosome with P-tRNA, state IV | 分子名称: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | 著者 | Crowe-McAuliffe, C, Wilson, D.N. | 登録日 | 2021-07-20 | 公開日 | 2022-02-23 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics. Nat Commun, 13, 2022
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7P7W
| N-acetylglucosamine kinase from Plesiomonas shigelloides compexed with alpha-N-acetylglucosamine and ADP | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Roy, S, Isupov, M.N, Harmer, N.J, Ames, J.R. | 登録日 | 2021-07-20 | 公開日 | 2022-08-03 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases J.Biol.Chem., 2022
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7P97
| Structure of 3-phospho-D-glycerate guanylyltransferase with product 3-GPPG bound | 分子名称: | 3-(guanosine-5'-diphospho)-D-glycerate, 3-phospho-D-glycerate guanylyltransferase, CHLORIDE ION, ... | 著者 | Palm, G.J, Berndt, L, Lammers, M. | 登録日 | 2021-07-26 | 公開日 | 2022-02-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Diversification by CofC and Control by CofD Govern Biosynthesis and Evolution of Coenzyme F 420 and Its Derivative 3PG-F 420. Mbio, 13, 2022
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7P9L
| N-acetylglucosamine kinase from Plesiomonas shigelloides compexed with alpha-N-acetylglucosamine-6-phosphate | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-6-O-phosphono-beta-D-glucopyranose, ... | 著者 | Roy, S, Isupov, M.N, Harmer, N.J, Ames, J.R. | 登録日 | 2021-07-27 | 公開日 | 2022-08-10 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases J.Biol.Chem., 2022
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7P9P
| N-acetylglucosamine kinase from Plesiomonas shigelloides compexed with alpha-N-acetylglucosamine and AMP-PNP inhibitor | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... | 著者 | Roy, S, Isupov, M.N, Harmer, N.J, Ames, J.R. | 登録日 | 2021-07-27 | 公開日 | 2022-08-10 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases J.Biol.Chem., 2022
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7P9Y
| N-acetylglucosamine kinase from Plesiomonas shigelloides compexed with alpha-N-acetylglucosamine | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-glucopyranose, ... | 著者 | Roy, S, Isupov, M.N, Harmer, N.J, Ames, J.R. | 登録日 | 2021-07-28 | 公開日 | 2022-08-10 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases J.Biol.Chem., 2022
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7PA1
| Structure of N-acetylglucosamine kinase from Plesiomonas shigelloides in complex with AMP-PNP in the absence of N-acetylglucoseamine substrate | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Roy, S, Isupov, M.N, Harmer, N.J, Ames, J.R. | 登録日 | 2021-07-28 | 公開日 | 2022-08-10 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases J.Biol.Chem., 2022
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7PA2
| PARK7 with inhibitor 8RK64 | 分子名称: | (3~{S})-~{N}-[5-[2-[(azanylidene-$l^{4}-azanylidene)amino]ethanoyl]-6,7-dihydro-4~{H}-[1,3]thiazolo[5,4-c]pyridin-2-yl]-1-(iminomethyl)pyrrolidine-3-carboxamide, Parkinson disease protein 7 | 著者 | Kim, R.Q, Jia, Y, Sapmaz, A, Geurink, P.P. | 登録日 | 2021-07-28 | 公開日 | 2022-08-10 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | 主引用文献 | Chemical Toolkit for PARK7: Potent, Selective, and High-Throughput. J.Med.Chem., 65, 2022
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7PA3
| PARK7 with covalent inhibitor JYQ-88 | 分子名称: | (3~{S})-~{N}-[5-[2-[(azanylidene-$l^{4}-azanylidene)amino]ethanoyl]-6,7-dihydro-4~{H}-[1,3]thiazolo[5,4-c]pyridin-2-yl]-1-(iminomethyl)pyrrolidine-3-carboxamide, Parkinson disease protein 7 | 著者 | Kim, R.Q, Jia, Y, Sapmaz, A, Geurink, P.P. | 登録日 | 2021-07-28 | 公開日 | 2022-08-10 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Chemical Toolkit for PARK7: Potent, Selective, and High-Throughput. J.Med.Chem., 65, 2022
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7PA6
| JC polyomavirus VP1 in complex with scFv 27C11 | 分子名称: | Major capsid protein VP1, scFv 27C11 antibody heavy chain | 著者 | Harprecht, C, Stroeh, L.J, Nagel, F, Freytag, J, Stehle, T. | 登録日 | 2021-07-29 | 公開日 | 2023-02-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural characterization of human neutralizing antibodies against JC and BK polyomavirus To Be Published
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7PA7
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