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Yorodumi- PDB-4xsx: Crystal structure of CBR 703 bound to Escherichia coli RNA polyme... -
+Open data
-Basic information
Entry | Database: PDB / ID: 4xsx | ||||||
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Title | Crystal structure of CBR 703 bound to Escherichia coli RNA polymerase holoenzyme | ||||||
Components |
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Keywords | transcription/antibiotic / bacterial RNA polymerase antibiotic complex / transcription-antibiotic complex | ||||||
Function / homology | Function and homology information sigma factor antagonist complex / cytosolic DNA-directed RNA polymerase complex / regulation of DNA-templated transcription initiation / sigma factor activity / DNA-directed RNA polymerase complex / DNA-templated transcription initiation / ribonucleoside binding / DNA-directed 5'-3' RNA polymerase activity / DNA-directed RNA polymerase / response to heat ...sigma factor antagonist complex / cytosolic DNA-directed RNA polymerase complex / regulation of DNA-templated transcription initiation / sigma factor activity / DNA-directed RNA polymerase complex / DNA-templated transcription initiation / ribonucleoside binding / DNA-directed 5'-3' RNA polymerase activity / DNA-directed RNA polymerase / response to heat / protein dimerization activity / negative regulation of DNA-templated transcription / DNA-templated transcription / magnesium ion binding / DNA binding / zinc ion binding / cytoplasm / cytosol Similarity search - Function | ||||||
Biological species | Escherichia coli (E. coli) Escherichia coli O139:H28 (bacteria) Citrobacter koseri (bacteria) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / molecular replacement / Resolution: 3.708 Å | ||||||
Authors | Bae, B. / Darst, S.A. | ||||||
Citation | Journal: Proc.Natl.Acad.Sci.USA / Year: 2015 Title: CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition. Authors: Bae, B. / Nayak, D. / Ray, A. / Mustaev, A. / Landick, R. / Darst, S.A. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 4xsx.cif.gz | 1.4 MB | Display | PDBx/mmCIF format |
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PDB format | pdb4xsx.ent.gz | 1.1 MB | Display | PDB format |
PDBx/mmJSON format | 4xsx.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 4xsx_validation.pdf.gz | 1.2 MB | Display | wwPDB validaton report |
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Full document | 4xsx_full_validation.pdf.gz | 1.3 MB | Display | |
Data in XML | 4xsx_validation.xml.gz | 240.4 KB | Display | |
Data in CIF | 4xsx_validation.cif.gz | 319.8 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/xs/4xsx ftp://data.pdbj.org/pub/pdb/validation_reports/xs/4xsx | HTTPS FTP |
-Related structure data
Related structure data | 4xsyC 4xszC 4ljzS C: citing same article (ref.) S: Starting model for refinement |
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Similar structure data |
-Links
-Assembly
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
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