[English] 日本語
Yorodumi- PDB-1qlk: SOLUTION STRUCTURE OF CA(2+)-LOADED RAT S100B (BETABETA) NMR, 20 ... -
+Open data
-Basic information
Entry | Database: PDB / ID: 1qlk | ||||||
---|---|---|---|---|---|---|---|
Title | SOLUTION STRUCTURE OF CA(2+)-LOADED RAT S100B (BETABETA) NMR, 20 STRUCTURES | ||||||
Components | S-100 PROTEIN | ||||||
Keywords | CALCIUM-BINDING / S100BETA / S100B / EF-HAND / S100 PROTEIN / CALCIUM-BINDING PROTEIN / FOUR-HELIX BUNDLE | ||||||
Function / homology | Function and homology information negative regulation of skeletal muscle cell differentiation / TRAF6 mediated NF-kB activation / Advanced glycosylation endproduct receptor signaling / TAK1-dependent IKK and NF-kappa-B activation / adaptive thermogenesis / sympathetic neuron projection extension / positive regulation of myelination / RAGE receptor binding / response to methylmercury / astrocyte differentiation ...negative regulation of skeletal muscle cell differentiation / TRAF6 mediated NF-kB activation / Advanced glycosylation endproduct receptor signaling / TAK1-dependent IKK and NF-kappa-B activation / adaptive thermogenesis / sympathetic neuron projection extension / positive regulation of myelination / RAGE receptor binding / response to methylmercury / astrocyte differentiation / S100 protein binding / neuron projection extension / regulation of neuronal synaptic plasticity / positive regulation of synaptic transmission / response to glucocorticoid / ruffle / positive regulation of neuron differentiation / long-term synaptic potentiation / tau protein binding / memory / calcium-dependent protein binding / cellular response to hypoxia / positive regulation of canonical NF-kappaB signal transduction / regulation of cell shape / learning or memory / cell adhesion / positive regulation of apoptotic process / signaling receptor binding / neuronal cell body / positive regulation of cell population proliferation / calcium ion binding / perinuclear region of cytoplasm / protein homodimerization activity / extracellular space / zinc ion binding / extracellular region / identical protein binding / nucleus / cytoplasm Similarity search - Function | ||||||
Biological species | Rattus norvegicus (Norway rat) | ||||||
Method | SOLUTION NMR / SEE MAIN REFERENCE | ||||||
Authors | Drohat, A.C. / Baldisseri, D.M. / Rustandi, R.R. / Weber, D.J. | ||||||
Citation | Journal: Biochemistry / Year: 1998 Title: Solution structure of calcium-bound rat S100B(betabeta) as determined by nuclear magnetic resonance spectroscopy,. Authors: Drohat, A.C. / Baldisseri, D.M. / Rustandi, R.R. / Weber, D.J. #1: Journal: Biochemistry / Year: 1996 Title: Solution Structure of Rat Apo-S100B(Beta Beta) as Determined by NMR Spectroscopy Authors: Drohat, A.C. / Amburgey, J.C. / Abildgaard, F. / Starich, M.R. / Baldisseri, D. / Weber, D.J. #2: Journal: J.Biomol.NMR / Year: 1995 Title: 1H, 13C and 15N NMR Assignments and Solution Secondary Structure of Rat Apo-S100 Beta Authors: Amburgey, J.C. / Abildgaard, F. / Starich, M.R. / Shah, S. / Hilt, D.C. / Weber, D.J. | ||||||
History |
|
-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
---|
-Downloads & links
-Download
PDBx/mmCIF format | 1qlk.cif.gz | 1.1 MB | Display | PDBx/mmCIF format |
---|---|---|---|---|
PDB format | pdb1qlk.ent.gz | 950.1 KB | Display | PDB format |
PDBx/mmJSON format | 1qlk.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 1qlk_validation.pdf.gz | 344.9 KB | Display | wwPDB validaton report |
---|---|---|---|---|
Full document | 1qlk_full_validation.pdf.gz | 572.7 KB | Display | |
Data in XML | 1qlk_validation.xml.gz | 59.9 KB | Display | |
Data in CIF | 1qlk_validation.cif.gz | 90.4 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/ql/1qlk ftp://data.pdbj.org/pub/pdb/validation_reports/ql/1qlk | HTTPS FTP |
-Related structure data
Similar structure data |
---|
-Links
-Assembly
Deposited unit |
| |||||||||
---|---|---|---|---|---|---|---|---|---|---|
1 |
| |||||||||
NMR ensembles |
|
-Components
#1: Protein | Mass: 10758.048 Da / Num. of mol.: 2 / Fragment: SUBUNITS A AND B Source method: isolated from a genetically manipulated source Source: (gene. exp.) Rattus norvegicus (Norway rat) / Gene: S100BETA / Plasmid: PET11B / Production host: Escherichia coli (E. coli) / Strain (production host): HMS174 (DE3) / References: UniProt: P04631 #2: Chemical | ChemComp-CA / |
---|
-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR |
---|---|
NMR experiment | Type: SEE MAIN REFERENCE |
NMR details | Text: PLEASE SEE MAIN REFERENCE FOR DETAILS |
-Sample preparation
Details | Contents: WATER |
---|---|
Sample conditions | Ionic strength: 22mM / pH: 6.5 / Pressure: ATMOSPHERIC atm / Temperature: 310 K |
Crystal grow | *PLUS Method: other / Details: NMR |
-NMR measurement
NMR spectrometer | Type: Bruker DMX / Manufacturer: Bruker / Model: DMX / Field strength: 600.13 MHz |
---|
-Processing
Software |
| ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NMR software |
| ||||||||||||
Refinement | Method: SEE MAIN REFERENCE / Software ordinal: 1 | ||||||||||||
NMR ensemble | Conformer selection criteria: SEE MAIN REFERENCE / Conformers calculated total number: 20 / Conformers submitted total number: 20 |