multicellular organism development / positive regulation of mitochondrial membrane potential / protein serine/threonine kinase activator activity / positive regulation of protein-containing complex assembly / positive regulation of protein serine/threonine kinase activity / positive regulation of peptidyl-serine phosphorylation / cellular response to tumor necrosis factor / positive regulation of cell population proliferation / negative regulation of apoptotic process / protein kinase binding ...multicellular organism development / positive regulation of mitochondrial membrane potential / protein serine/threonine kinase activator activity / positive regulation of protein-containing complex assembly / positive regulation of protein serine/threonine kinase activity / positive regulation of peptidyl-serine phosphorylation / cellular response to tumor necrosis factor / positive regulation of cell population proliferation / negative regulation of apoptotic process / protein kinase binding / endoplasmic reticulum / protein-containing complex / nucleoplasm / identical protein binding / cytosol Similarity search - Function
P14 IS INVOLVED IN RARE FORMS OF LEUKEMIA BUT ITS CELLULAR ROLE REMAINS UNKNOWN. THERE EXISTS EVIDENCE FOR DIMER FORMATION IN SOLUTION BUT THE PROTEIN IS PRESENT AS A MONOMER IN THE ASYMMETRIC UNIT. A TIGHT DIMER CONTACT IS GENERATED BY THE TWO-FOLD CRYSTAL C-AXIS.
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Components
#1: Protein
ONCOGENEPRODUCTP14TCL1
Mass: 13475.537 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Homo sapiens (human) / Cell: T-CELL / References: UniProt: P56279
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