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Yorodumi- PDB-1iva: STRUCTURE-ACTIVITY RELATIONSHIPS FOR P-TYPE CALCIUM CHANNEL SELEC... -
+Open data
-Basic information
Entry | Database: PDB / ID: 1iva | ||||||
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Title | STRUCTURE-ACTIVITY RELATIONSHIPS FOR P-TYPE CALCIUM CHANNEL SELECTIVE OMEGA-AGATOXINS | ||||||
Components | OMEGA-AGATOXIN-IVA | ||||||
Keywords | NEUROTOXIN | ||||||
Function / homology | Function and homology information host cell presynaptic membrane / calcium channel inhibitor activity / toxin activity / extracellular region Similarity search - Function | ||||||
Biological species | Agelenopsis aperta (spider) | ||||||
Method | SOLUTION NMR | ||||||
Authors | Reily, M.D. / Holub, K.E. | ||||||
Citation | Journal: Nat.Struct.Biol. / Year: 1994 Title: Structure-activity relationships for P-type calcium channel-selective omega-agatoxins. Authors: Reily, M.D. / Holub, K.E. / Gray, W.R. / Norris, T.M. / Adams, M.E. #1: Journal: To be Published Title: The Solution Structure of Omega-Aga-Ivb, a P-Type Calcium Channel Antagonist from Venom of Agelenopsis Aperta Authors: Reily, M.D. / Thanabal, V. / Adams, M.E. #2: Journal: Nature / Year: 1992 Title: P-Type Calcium Channels Blocked by the Spider Toxin Omega-Aga-Iva Authors: Mintz, I.M. / Venema, V.J. / Swiderek, K.M. / Lee, T.D. / Bean, B.P. / Adams, M.E. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 1iva.cif.gz | 227.7 KB | Display | PDBx/mmCIF format |
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PDB format | pdb1iva.ent.gz | 194.9 KB | Display | PDB format |
PDBx/mmJSON format | 1iva.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 1iva_validation.pdf.gz | 353.1 KB | Display | wwPDB validaton report |
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Full document | 1iva_full_validation.pdf.gz | 459.1 KB | Display | |
Data in XML | 1iva_validation.xml.gz | 16.8 KB | Display | |
Data in CIF | 1iva_validation.cif.gz | 26.6 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/iv/1iva ftp://data.pdbj.org/pub/pdb/validation_reports/iv/1iva | HTTPS FTP |
-Related structure data
Similar structure data |
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-Links
-Assembly
Deposited unit |
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1 |
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Atom site foot note | 1: THR 32 - ASN 33 MODEL 4 OMEGA = 221.36 PEPTIDE BOND DEVIATES SIGNIFICANTLY FROM TRANS CONFORMATION 2: ASN 33 - CYS 34 MODEL 4 OMEGA = 216.16 PEPTIDE BOND DEVIATES SIGNIFICANTLY FROM TRANS CONFORMATION 3: THR 32 - ASN 33 MODEL 9 OMEGA = 211.80 PEPTIDE BOND DEVIATES SIGNIFICANTLY FROM TRANS CONFORMATION 4: TRP 14 - GLY 15 MODEL 12 OMEGA = 149.94 PEPTIDE BOND DEVIATES SIGNIFICANTLY FROM TRANS CONFORMATION 5: LYS 7 - ASP 8 MODEL 13 OMEGA = 210.54 PEPTIDE BOND DEVIATES SIGNIFICANTLY FROM TRANS CONFORMATION | |||||||||
NMR ensembles |
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-Components
#1: Protein/peptide | Mass: 5220.393 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Agelenopsis aperta (spider) / References: UniProt: P30288 |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR |
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-Sample preparation
Crystal grow | *PLUS Method: other / Details: NMR |
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-Processing
NMR software | Name: Discover / Developer: BIOSYM TECHNOLOGIES / Classification: refinement |
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NMR ensemble | Conformers submitted total number: 16 |