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- PDB-2ccx: DETERMINATION OF THE NUCLEAR MAGNETIC RESONANCE SOLUTION STRUCTUR... -

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Entry
Database: PDB / ID: 2ccx
TitleDETERMINATION OF THE NUCLEAR MAGNETIC RESONANCE SOLUTION STRUCTURE OF CARDIOTOXIN CTX IIB FROM NAJA MOSSAMBICA MOSSAMBICA
ComponentsCARDIOTOXIN CTX IIB
KeywordsCARDIOTOXIN
Function / homology
Function and homology information


cytolysis / other organism cell membrane / : / toxin activity / extracellular region / membrane
Similarity search - Function
Snake cytotoxin, cobra-type / Snake three-finger toxin / Snake toxins signature. / Snake toxin, conserved site / CD59 / CD59 / Ribbon / Mainly Beta
Similarity search - Domain/homology
Biological speciesNaja mossambica (Mozambique cobra)
MethodSOLUTION NMR
AuthorsO'Connell, J. / Wuthrich, K.
CitationJournal: Eur.J.Biochem. / Year: 1993
Title: Determination of the nuclear-magnetic-resonance solution structure of cardiotoxin CTX IIb from Naja mossambica mossambica.
Authors: O'Connell, J.F. / Bougis, P.E. / Wuthrich, K.
History
DepositionFeb 1, 1993Processing site: BNL
Revision 1.0Jan 31, 1994Provider: repository / Type: Initial release
Revision 1.1Mar 24, 2008Group: Version format compliance
Revision 1.2Jul 13, 2011Group: Version format compliance
Revision 1.3Mar 9, 2022Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Other
Category: database_2 / pdbx_database_status ...database_2 / pdbx_database_status / pdbx_nmr_software / pdbx_struct_assembly / pdbx_struct_oper_list
Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.process_site / _pdbx_nmr_software.name

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Structure visualization

Structure viewerMolecule:
MolmilJmol/JSmol

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Assembly

Deposited unit
A: CARDIOTOXIN CTX IIB


Theoretical massNumber of molelcules
Total (without water)6,8371
Polymers6,8371
Non-polymers00
Water00
1


  • Idetical with deposited unit
  • defined by author
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
NMR ensembles
DataCriteria
Number of conformers (submitted / calculated)20 / -
Representative

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Components

#1: Protein CARDIOTOXIN CTX IIB


Mass: 6837.477 Da / Num. of mol.: 1
Source method: isolated from a genetically manipulated source
Source: (gene. exp.) Naja mossambica (Mozambique cobra) / References: UniProt: P01467

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Experimental details

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Experiment

ExperimentMethod: SOLUTION NMR

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Sample preparation

Crystal grow
*PLUS
Method: other / Details: NMR

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Processing

NMR software
NameVersionDeveloperClassification
DIANAGUNTERT,BRAUN,WUTHRICHrefinement
FANTOMSCHAUMAN,BRAUN,WUTHRICHrefinement
Amber3PEARLMAN,CASE,CALDWELL,SIEBEL,SINGH,WEINER,KOLLMANrefinement
NMR ensembleConformers submitted total number: 20

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