Vaccine-elicited NHP FP-targeting neutralizing antibody A12V163-a.02 in complex with HIV fusion peptide (residue 512-519)
要素
Antibody A12V163-a.02 heavy chain
Antibody A12V163-a.02 light chain
HIV fusion peptide residue 512-519
キーワード
IMMUNE SYSTEM (免疫系) / HIV (ヒト免疫不全ウイルス) / neutralizing (中和抗体) / NHP / FP / Fusion Peptide (膜融合タンパク質) / vaccine (ワクチン)
機能・相同性
機能・相同性情報
Synthesis and processing of ENV and VPU / evasion of host immune response / Alpha-defensins / Dectin-2 family / Binding and entry of HIV virion / positive regulation of plasma membrane raft polarization / positive regulation of receptor clustering / positive regulation of establishment of T cell polarity / virus-mediated perturbation of host defense response / host cell endosome membrane ...Synthesis and processing of ENV and VPU / evasion of host immune response / Alpha-defensins / Dectin-2 family / Binding and entry of HIV virion / positive regulation of plasma membrane raft polarization / positive regulation of receptor clustering / positive regulation of establishment of T cell polarity / virus-mediated perturbation of host defense response / host cell endosome membrane / actin filament organization / Assembly Of The HIV Virion / Budding and maturation of HIV virion / clathrin-dependent endocytosis of virus by host cell / viral protein processing / symbiont entry into host cell / fusion of virus membrane with host plasma membrane / fusion of virus membrane with host endosome membrane / エンベロープ (ウイルス) / virion attachment to host cell / host cell plasma membrane / virion membrane / structural molecule activity / 生体膜 類似検索 - 分子機能
Envelope glycoprotein Gp160 / Retroviral envelope protein / Retroviral envelope protein GP41-like / Gp120 core superfamily / Gp120 (HIV) / Human immunodeficiency virus 1, envelope glycoprotein Gp120 類似検索 - ドメイン・相同性
ジャーナル: To Be Published タイトル: Vaccine-elicited NHP FP-targeting neutralizing antibody A12V163-a.02 in complex with HIV fusion peptide (residue 512-519) 著者: Xu, K. / Liu, K. / Kwong, P.D.