登録情報 データベース : PDB / ID : 5w93 構造の表示 ダウンロードとリンクタイトル p130Cas complex with paxillin LD1 要素Breast cancer anti-estrogen resistance protein 1 Paxillin 詳細キーワード CELL ADHESION (細胞接着) / p130Cas / BCAR1 / paxillin / Focal Adhesion機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
BH4 domain binding / Localization of the PINCH-ILK-PARVIN complex to focal adhesions / Regulation of cytoskeletal remodeling and cell spreading by IPP complex components / PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases / antigen receptor-mediated signaling pathway / GAB1 signalosome / cellular response to endothelin / Downstream signal transduction / response to peptide / Smooth Muscle Contraction ... BH4 domain binding / Localization of the PINCH-ILK-PARVIN complex to focal adhesions / Regulation of cytoskeletal remodeling and cell spreading by IPP complex components / PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases / antigen receptor-mediated signaling pathway / GAB1 signalosome / cellular response to endothelin / Downstream signal transduction / response to peptide / Smooth Muscle Contraction / p130Cas linkage to MAPK signaling for integrins / negative regulation of substrate adhesion-dependent cell spreading / endothelin receptor signaling pathway / : / vinculin binding / hepatocyte growth factor receptor signaling pathway / MAP-kinase scaffold activity / neuropilin binding / VEGFA-VEGFR2 Pathway / focal adhesion assembly / lamellipodium assembly / growth hormone receptor signaling pathway / cellular response to hepatocyte growth factor stimulus / branching morphogenesis of an epithelial tube / cell leading edge / neurotrophin TRK receptor signaling pathway / platelet-derived growth factor receptor signaling pathway / endothelial cell migration / cellular response to nitric oxide / positive regulation of protein kinase activity / vascular endothelial growth factor receptor signaling pathway / stress fiber / positive regulation of stress fiber assembly / cytoskeleton organization / ruffle / cell chemotaxis / substrate adhesion-dependent cell spreading / transforming growth factor beta receptor signaling pathway / positive regulation of endothelial cell migration / actin filament organization / integrin-mediated signaling pathway / transcription coregulator activity / B cell receptor signaling pathway / epidermal growth factor receptor signaling pathway / beta-catenin binding / SH3 domain binding / peptidyl-tyrosine phosphorylation / cell surface receptor protein tyrosine kinase signaling pathway / positive regulation of angiogenesis / 遊走 / cell-cell junction / signaling receptor complex adaptor activity / マイクロフィラメント / integrin binding / insulin receptor signaling pathway / lamellipodium / 細胞皮質 / regulation of cell shape / actin cytoskeleton organization / protein phosphatase binding / 細胞接着 / positive regulation of cell migration / G protein-coupled receptor signaling pathway / 神経繊維 / protein domain specific binding / focal adhesion / protein-containing complex binding / protein kinase binding / 生体膜 / metal ion binding / 細胞膜 / 細胞質基質 / 細胞質 類似検索 - 分子機能 Breast cancer anti-estrogen resistance protein 1 / BCAR1, SH3 domain / Serine rich protein interaction domain / CAS family, C-terminal / CAS family / CAS, serine rich four helix bundle domain superfamily / Serine rich protein interaction domain / Crk-Associated Substrate C-terminal domain / Paxillin / : ... Breast cancer anti-estrogen resistance protein 1 / BCAR1, SH3 domain / Serine rich protein interaction domain / CAS family, C-terminal / CAS family / CAS, serine rich four helix bundle domain superfamily / Serine rich protein interaction domain / Crk-Associated Substrate C-terminal domain / Paxillin / : / : / Paxillin family / Alpha-catenin/vinculin-like / LIM zinc-binding domain signature. / LIM domain / Zinc-binding domain present in Lin-11, Isl-1, Mec-3. / Zinc finger, LIM-type / LIM domain profile. / Four Helix Bundle (Hemerythrin (Met), subunit A) / SH3ドメイン / Src homology 3 domains / SH3-like domain superfamily / Src homology 3 (SH3) domain profile. / SH3ドメイン / Up-down Bundle / Mainly Alpha 類似検索 - ドメイン・相同性 Breast cancer anti-estrogen resistance protein 1 / Paxillin 類似検索 - 構成要素生物種 Mus musculus (ハツカネズミ)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 2.001 Å 詳細データ登録者 Miller, D.J. / Zheng, J.J. 引用ジャーナル : J. Biol. Chem. / 年 : 2017タイトル : Structural and functional insights into the interaction between the Cas family scaffolding protein p130Cas and the focal adhesion-associated protein paxillin.著者 : Zhang, C. / Miller, D.J. / Guibao, C.D. / Donato, D.M. / Hanks, S.K. / Zheng, J.J. 履歴 登録 2017年6月22日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2017年9月6日 Provider : repository / タイプ : Initial release改定 1.1 2017年12月6日 Group : Database references / カテゴリ : citation / citation_authorItem : _citation.country / _citation.journal_abbrev ... _citation.country / _citation.journal_abbrev / _citation.journal_id_ASTM / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year / _citation_author.name 改定 1.2 2023年10月4日 Group : Data collection / Database references / Refinement descriptionカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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