- PDB-2yub: Solution structure of the PDZ domain from mouse LIM domain kinase -
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基本情報
登録情報
データベース: PDB / ID: 2yub
タイトル
Solution structure of the PDZ domain from mouse LIM domain kinase
要素
LIM domain kinase 2
キーワード
TRANSFERASE (転移酵素) / PDZ domain (PDZドメイン) / LIMK-2 / Structural Genomics (構造ゲノミクス) / NPPSFA / National Project on Protein Structural and Functional Analyses / RIKEN Structural Genomics/Proteomics Initiative / RSGI
機能・相同性
機能・相同性情報
cornea development in camera-type eye / head development / astral microtubule organization / cis-Golgi network / 紡錘体 / actin cytoskeleton organization / 精子形成 / non-specific serine/threonine protein kinase / protein kinase activity / protein phosphorylation ...cornea development in camera-type eye / head development / astral microtubule organization / cis-Golgi network / 紡錘体 / actin cytoskeleton organization / 精子形成 / non-specific serine/threonine protein kinase / protein kinase activity / protein phosphorylation / protein serine/threonine kinase activity / ATP binding / metal ion binding / 細胞核 / 細胞質 類似検索 - 分子機能
LIM zinc-binding domain signature. / LIM domain / Zinc-binding domain present in Lin-11, Isl-1, Mec-3. / Zinc finger, LIM-type / LIM domain profile. / PDZドメイン / Pdz3 Domain / PDZドメイン / PDZ domain profile. / Domain present in PSD-95, Dlg, and ZO-1/2. ...LIM zinc-binding domain signature. / LIM domain / Zinc-binding domain present in Lin-11, Isl-1, Mec-3. / Zinc finger, LIM-type / LIM domain profile. / PDZドメイン / Pdz3 Domain / PDZドメイン / PDZ domain profile. / Domain present in PSD-95, Dlg, and ZO-1/2. / PDZドメイン / PDZ superfamily / Protein tyrosine and serine/threonine kinase / Serine-threonine/tyrosine-protein kinase, catalytic domain / Roll / Protein kinase, ATP binding site / Protein kinases ATP-binding region signature. / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily / Mainly Beta 類似検索 - ドメイン・相同性
手法: torsion angle dynamics / ソフトェア番号: 1 詳細: The structures are based on a total of 1438 restraints, 1347 are NOE-derived distance constraints, 91 dihedral angle restraints.
代表構造
選択基準: lowest energy
NMRアンサンブル
コンフォーマー選択の基準: structures with the least restraint violations, target function 計算したコンフォーマーの数: 100 / 登録したコンフォーマーの数: 20