登録情報 データベース : PDB / ID : 2v5a 構造の表示 ダウンロードとリンクタイトル CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 3 要素BIOTIN CARBOXYLASE 詳細 キーワード LIGASE (リガーゼ) / FATTY ACID BIOSYNTHESIS (脂肪酸の合成) / BIOTIN CARBOXYLASE / NUCLEOTIDE-BINDING / ATP-BINDING / ANTIBACTERIAL (抗生物質) / LIPID SYNTHESIS (脂質代謝) / FAS / BIOTIN (ビオチン) / BACTERIAL (細菌) / INHIBITOR (酵素阻害剤)機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
biotin carboxylase / acetyl-CoA carboxylase complex / biotin carboxylase activity / malonyl-CoA biosynthetic process / acetyl-CoA carboxylase activity / negative regulation of fatty acid biosynthetic process / fatty acid biosynthetic process / protein homodimerization activity / ATP binding / metal ion binding ... biotin carboxylase / acetyl-CoA carboxylase complex / biotin carboxylase activity / malonyl-CoA biosynthetic process / acetyl-CoA carboxylase activity / negative regulation of fatty acid biosynthetic process / fatty acid biosynthetic process / protein homodimerization activity / ATP binding / metal ion binding / 細胞質基質 / 細胞質 類似検索 - 分子機能 Acetyl-CoA carboxylase, biotin carboxylase / Biotin carboxylase-like, N-terminal domain / Biotin carboxylase, C-terminal / Biotin carboxylation domain / Biotin carboxylase, N-terminal domain / Biotin carboxylase C-terminal domain / Biotin carboxylation domain profile. / Biotin carboxylase C-terminal domain / Rossmann fold - #20 / Carbamoyl-phosphate synthase subdomain signature 1. ... Acetyl-CoA carboxylase, biotin carboxylase / Biotin carboxylase-like, N-terminal domain / Biotin carboxylase, C-terminal / Biotin carboxylation domain / Biotin carboxylase, N-terminal domain / Biotin carboxylase C-terminal domain / Biotin carboxylation domain profile. / Biotin carboxylase C-terminal domain / Rossmann fold - #20 / Carbamoyl-phosphate synthase subdomain signature 1. / Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain / Carbamoyl-phosphate synthase L chain, ATP binding domain / Rudiment single hybrid motif / ATP-grasp fold, A domain / ATP-grasp fold, B domain / ATP-grasp fold, subdomain 1 / Pre-ATP-grasp domain superfamily / ATP-grasp fold / ATP-grasp fold profile. / D-amino Acid Aminotransferase; Chain A, domain 1 / Dna Ligase; domain 1 / Carbamoyl-phosphate synthase subdomain signature 2. / ロスマンフォールド / 2-Layer Sandwich / 3-Layer(aba) Sandwich / Alpha Beta 類似検索 - ドメイン・相同性生物種 ESCHERICHIA COLI (大腸菌)手法 X線回折 / 分子置換 / 解像度 : 2.31 Å 詳細データ登録者 Mochalkin, I. / Miller, J.R. 引用ジャーナル : Proc.Natl.Acad.Sci.USA / 年 : 2009タイトル : A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore.著者: Miller, J.R. / Dunham, S. / Mochalkin, I. / Banotai, C. / Bowman, M. / Buist, S. / Dunkle, B. / Hanna, D. / Harwood, H.J. / Huband, M.D. / Karnovsky, A. / Kuhn, M. / Limberakis, C. / Liu, J.Y. ... 著者 : Miller, J.R. / Dunham, S. / Mochalkin, I. / Banotai, C. / Bowman, M. / Buist, S. / Dunkle, B. / Hanna, D. / Harwood, H.J. / Huband, M.D. / Karnovsky, A. / Kuhn, M. / Limberakis, C. / Liu, J.Y. / Mehrens, S. / Mueller, W.T. / Narasimhan, L. / Ogden, A. / Ohren, J. / Prasad, J.V. / Shelly, J.A. / Skerlos, L. / Sulavik, M. / Thomas, V.H. / Vanderroest, S. / Wang, L. / Wang, Z. / Whitton, A. / Zhu, T. / Stover, C.K. 履歴 登録 2008年10月2日 登録サイト : PDBE / 処理サイト : PDBE改定 1.0 2009年1月13日 Provider : repository / タイプ : Initial release改定 1.1 2011年5月8日 Group : Version format compliance改定 1.2 2011年7月13日 Group : Version format compliance改定 1.3 2023年12月13日 Group : Data collection / Database references ... Data collection / Database references / Other / Refinement description カテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf
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