- PDB-2fy8: Crystal structure of MthK rck domain in its ligand-free gating-ri... -
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基本情報
登録情報
データベース: PDB / ID: 2fy8
タイトル
Crystal structure of MthK rck domain in its ligand-free gating-ring form
要素
Calcium-gated potassium channel mthK
キーワード
TRANSPORT PROTEIN (運搬体タンパク質) / Transport / Ionic channel (イオンチャネル) / Alternative initiation / Transmembrane (膜貫通型タンパク質) / Ion transport / Potassium (カリウム) / Potassium transport / Membrane (生体膜) / gating ring / closed conformation / partially open conformation / transition state (遷移状態)
機能・相同性
機能・相同性情報
monoatomic cation transmembrane transporter activity / potassium ion transport / identical protein binding / metal ion binding / 細胞膜 類似検索 - 分子機能
The biological assembly is an octamer. There are two tetramers in an asymmetric unit. The first octamer can be generated from the first tetramer (polypeptide chain A, B, C and D) by the operation: ROTATION MATRIX -1.000 0.000 0.000 0.000 1.000 0.000 0.000 0.000 -1.000 TRANSLATION VECTOR 0.00000 0.00000 126.374 The first octamer has the 422 symmetry, representing the closed conformation of mthK gating ring. The second octamer can be generated from the second tetramer (polypeptide chain E, F, G and H) by the operation: ROTATION MATRIX -1.000 0.000 0.000 0.000 1.000 0.000 0.000 0.000 -1.000 TRANSLATION VECTOR 0.00000 0.00000 126.374 The second octamer is an asymmetric, parcially open mthK gating ring, which might represent a gating ring conformation in transition state.