登録情報 データベース : PDB / ID : 8oxx 構造の表示 ダウンロードとリンクタイトル Transglutaminase 3 in complex with inhibitor Z-don and DH patient-derived Fab DH63-B02 要素(Antibody fab fragment ...) x 2 Protein-glutamine gamma-glutamyltransferase E 27 kDa non-catalytic chain 詳細キーワード TRANSFERASE / Transglutaminase / TGM3 / TG3 / Transglutaminase 3 / enzyme / antibody / dermatitis herpetiformis / inhibitor / Z-don / IGHV3-9 / IGLV6-57機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
protein-glutamine gamma-glutamyltransferase / protein-glutamine gamma-glutamyltransferase activity / peptide cross-linking / hair follicle morphogenesis / acyltransferase activity / keratinization / extrinsic component of cytoplasmic side of plasma membrane / catalytic activity / keratinocyte differentiation / protein modification process ... protein-glutamine gamma-glutamyltransferase / protein-glutamine gamma-glutamyltransferase activity / peptide cross-linking / hair follicle morphogenesis / acyltransferase activity / keratinization / extrinsic component of cytoplasmic side of plasma membrane / catalytic activity / keratinocyte differentiation / protein modification process / calcium ion binding / structural molecule activity / protein-containing complex / extracellular exosome / cytoplasm 類似検索 - 分子機能 : / Transglutaminase, N-terminal / Transglutaminase, C-terminal / Transglutaminase, active site / Protein-glutamine gamma-glutamyltransferase, animal / Transglutaminase, C-terminal domain superfamily / Transglutaminase family / Transglutaminase family, C-terminal ig like domain / Transglutaminases active site. / Transglutaminase-like superfamily ... : / Transglutaminase, N-terminal / Transglutaminase, C-terminal / Transglutaminase, active site / Protein-glutamine gamma-glutamyltransferase, animal / Transglutaminase, C-terminal domain superfamily / Transglutaminase family / Transglutaminase family, C-terminal ig like domain / Transglutaminases active site. / Transglutaminase-like superfamily / Transglutaminase/protease-like homologues / Transglutaminase-like / Transglutaminase-like superfamily / Papain-like cysteine peptidase superfamily / Immunoglobulin E-set / Immunoglobulin-like fold 類似検索 - ドメイン・相同性 D-PROLINE / D-VALINE / METHYL L-LEUCINATE / 5-OXO-L-NORLEUCINE / benzyl hydrogen carbonate / Protein-glutamine gamma-glutamyltransferase E 類似検索 - 構成要素生物種 Homo sapiens (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 2.5 Å 詳細データ登録者 Heggelund, J.E. / Sollid, L.M. 資金援助 ノルウェー, 3件 詳細 詳細を隠す組織 認可番号 国 Other government 2020027 ノルウェー Other private SKGJ-MED-017 ノルウェー Other government WL-IMMUNOLOGY ノルウェー
引用ジャーナル : Nat Commun / 年 : 2023タイトル : Autoantibody binding and unique enzyme-substrate intermediate conformation of human transglutaminase 3.著者 : Heggelund, J.E. / Das, S. / Stamnaes, J. / Iversen, R. / Sollid, L.M. 履歴 登録 2023年5月2日 登録サイト : PDBE / 処理サイト : PDBE改定 1.0 2023年10月18日 Provider : repository / タイプ : Initial release改定 2.0 2023年11月15日 Group : Atomic model / Data collectionカテゴリ : atom_site / atom_site_anisotrop ... atom_site / atom_site_anisotrop / chem_comp_atom / chem_comp_bond Item : _atom_site.auth_atom_id / _atom_site.label_atom_id ... _atom_site.auth_atom_id / _atom_site.label_atom_id / _atom_site_anisotrop.pdbx_auth_atom_id / _atom_site_anisotrop.pdbx_label_atom_id / _chem_comp_atom.atom_id / _chem_comp_bond.atom_id_1 / _chem_comp_bond.atom_id_2