- PDB-8d1w: Crystal structure of Plasmodium falciparum GRP78 in complex with ... -
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Basic information
Entry
Database: PDB / ID: 8d1w
Title
Crystal structure of Plasmodium falciparum GRP78 in complex with (2R,3R,4S,5R)-2-(6-amino-8-((2-chlorobenzyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
Components
Chaperone DnaK
Keywords
CHAPERONE / ATPase
Function / homology
Function and homology information
endoplasmic reticulum chaperone complex / endoplasmic reticulum unfolded protein response / ATP-dependent protein folding chaperone / endoplasmic reticulum lumen / ATP binding / membrane / nucleus Similarity search - Function
Endoplasmic reticulum chaperone BIP, nucleotide-binding domain / Heat shock hsp70 proteins family signature 2. / Heat shock hsp70 proteins family signature 1. / Heat shock hsp70 proteins family signature 3. / Heat shock protein 70, conserved site / Heat shock protein 70kD, peptide-binding domain superfamily / Heat shock protein 70 family / Hsp70 protein / Heat shock protein 70kD, C-terminal domain superfamily / ATPase, nucleotide binding domain Similarity search - Domain/homology
Resolution: 2.1→45.66 Å / Cor.coef. Fo:Fc: 0.95 / Cor.coef. Fo:Fc free: 0.939 / SU B: 3.481 / SU ML: 0.093 / Cross valid method: THROUGHOUT / ESU R: 0.156 / ESU R Free: 0.144 / Stereochemistry target values: MAXIMUM LIKELIHOOD / Details: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS
Rfactor
Num. reflection
% reflection
Selection details
Rfree
0.22145
1824
4.9 %
RANDOM
Rwork
0.1897
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obs
0.19131
35168
99.95 %
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Solvent computation
Ion probe radii: 0.8 Å / Shrinkage radii: 0.8 Å / VDW probe radii: 1.2 Å / Solvent model: MASK