登録情報 データベース : PDB / ID : 7p74 構造の表示 ダウンロードとリンクタイトル The PDZ domain of SYNJ2BP complexed with the phosphorylated PDZ-binding motif of RSK1 要素Ribosomal protein S6 kinase alpha-1 Synaptojanin-2-binding protein,Annexin A2 詳細キーワード PEPTIDE BINDING PROTEIN / PDZ / complex機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
regulation of translation in response to stress / CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling / negative regulation of sprouting angiogenesis / AnxA2-p11 complex / membrane raft assembly / positive regulation of receptor-mediated endocytosis involved in cholesterol transport / positive regulation of vacuole organization / phospholipase A2 inhibitor activity / positive regulation of low-density lipoprotein particle clearance / positive regulation of vesicle fusion ... regulation of translation in response to stress / CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling / negative regulation of sprouting angiogenesis / AnxA2-p11 complex / membrane raft assembly / positive regulation of receptor-mediated endocytosis involved in cholesterol transport / positive regulation of vacuole organization / phospholipase A2 inhibitor activity / positive regulation of low-density lipoprotein particle clearance / positive regulation of vesicle fusion / hepatocyte proliferation / CREB phosphorylation / positive regulation of hepatic stellate cell activation / negative regulation of low-density lipoprotein particle receptor catabolic process / myelin sheath adaxonal region / positive regulation of plasma membrane repair / positive regulation of plasminogen activation / PCSK9-AnxA2 complex / ribosomal protein S6 kinase activity / regulation of Notch signaling pathway / cadherin binding involved in cell-cell adhesion / cornified envelope / Schmidt-Lanterman incisure / vesicle budding from membrane / TORC1 signaling / plasma membrane protein complex / Gastrin-CREB signalling pathway via PKC and MAPK / calcium-dependent phospholipid binding / osteoclast development / negative regulation of receptor internalization / RSK activation / Dissolution of Fibrin Clot / S100 protein binding / collagen fibril organization / negative regulation of TOR signaling / vesicle membrane / negative regulation of endothelial cell migration / epithelial cell apoptotic process / phosphatidylserine binding / ERK/MAPK targets / negative regulation of endothelial cell proliferation / positive regulation of receptor recycling / Recycling pathway of L1 / regulation of endocytosis / positive regulation of exocytosis / basement membrane / Smooth Muscle Contraction / regulation of neurogenesis / protein targeting / Rho protein signal transduction / cytoskeletal protein binding / fibrinolysis / lipid droplet / phosphatidylinositol-4,5-bisphosphate binding / Transcriptional and post-translational regulation of MITF-M expression and activity / protein serine/threonine/tyrosine kinase activity / Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation / lung development / negative regulation of angiogenesis / cell-matrix adhesion / Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells / response to activity / adherens junction / positive regulation of cell differentiation / mRNA transcription by RNA polymerase II / serine-type endopeptidase inhibitor activity / sarcolemma / negative regulation of ERK1 and ERK2 cascade / RNA polymerase II transcription regulator complex / nuclear matrix / calcium-dependent protein binding / azurophil granule lumen / late endosome membrane / melanosome / : / Senescence-Associated Secretory Phenotype (SASP) / positive regulation of cell growth / midbody / protease binding / vesicle / angiogenesis / basolateral plasma membrane / chemical synaptic transmission / mitochondrial outer membrane / early endosome / protein phosphorylation / non-specific serine/threonine protein kinase / endosome / lysosomal membrane / protein serine kinase activity / protein serine/threonine kinase activity / synapse / calcium ion binding / Neutrophil degranulation / negative regulation of apoptotic process / positive regulation of DNA-templated transcription / magnesium ion binding / cell surface / signal transduction / positive regulation of transcription by RNA polymerase II 類似検索 - 分子機能 Annexin A2 / Ribosomal S6 kinase, N-terminal catalytic domain / Ribosomal protein S6 kinase II / Annexin / Annexin repeat, conserved site / Annexin repeat signature. / Annexin / Annexin / Annexin repeats / Annexin repeat ... Annexin A2 / Ribosomal S6 kinase, N-terminal catalytic domain / Ribosomal protein S6 kinase II / Annexin / Annexin repeat, conserved site / Annexin repeat signature. / Annexin / Annexin / Annexin repeats / Annexin repeat / Annexin superfamily / Annexin repeat profile. / : / Annexin V; domain 1 / Protein kinase, C-terminal / Protein kinase C terminal domain / PDZ domain / Pdz3 Domain / Extension to Ser/Thr-type protein kinases / AGC-kinase, C-terminal / AGC-kinase C-terminal domain profile. / PDZ domain / PDZ domain profile. / Domain present in PSD-95, Dlg, and ZO-1/2. / PDZ domain / PDZ superfamily / Roll / Serine/threonine-protein kinase, active site / Serine/Threonine protein kinases active-site signature. / Protein kinase domain / Serine/Threonine protein kinases, catalytic domain / Protein kinase, ATP binding site / Protein kinases ATP-binding region signature. / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily / Orthogonal Bundle / Mainly Beta / Mainly Alpha 類似検索 - ドメイン・相同性 Annexin A2 / Synaptojanin-2-binding protein / Ribosomal protein S6 kinase alpha-1 類似検索 - 構成要素生物種 Homo sapiens (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 1.9 Å 詳細データ登録者 Gogl, G. / Cousido-Siah, A. / Trave, G. 引用ジャーナル : Nat Commun / 年 : 2022タイトル : Quantitative fragmentomics allow affinity mapping of interactomes.著者 : Gogl, G. / Zambo, B. / Kostmann, C. / Cousido-Siah, A. / Morlet, B. / Durbesson, F. / Negroni, L. / Eberling, P. / Jane, P. / Nomine, Y. / Zeke, A. / Ostergaard, S. / Monsellier, E. / Vincentelli, R. / Trave, G. 履歴 登録 2021年7月19日 登録サイト : PDBE / 処理サイト : PDBE改定 1.0 2022年7月27日 Provider : repository / タイプ : Initial release改定 1.1 2023年2月8日 Group : Database references / カテゴリ : citation / citation_authorItem : _citation.country / _citation.journal_abbrev ... _citation.country / _citation.journal_abbrev / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year 改定 1.2 2024年2月7日 Group : Data collection / Refinement descriptionカテゴリ : chem_comp_atom / chem_comp_bond / pdbx_initial_refinement_model改定 1.3 2024年11月20日 Group : Structure summaryカテゴリ : pdbx_entry_details / pdbx_modification_featureItem : _pdbx_entry_details.has_protein_modification
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