+Open data
-Basic information
Entry | Database: PDB / ID: 7ox2 | ||||||
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Title | Fab 6E2: hIL-9 complex | ||||||
Components |
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Keywords | CYTOKINE / IL-9 / complex | ||||||
Function / homology | Function and homology information interleukin-9 receptor binding / Interleukin-9 signaling / positive regulation of interleukin-5 production / regulation of receptor signaling pathway via JAK-STAT / B cell proliferation / immunoglobulin mediated immune response / regulation of peptidyl-tyrosine phosphorylation / B cell differentiation / cytokine activity / growth factor activity ...interleukin-9 receptor binding / Interleukin-9 signaling / positive regulation of interleukin-5 production / regulation of receptor signaling pathway via JAK-STAT / B cell proliferation / immunoglobulin mediated immune response / regulation of peptidyl-tyrosine phosphorylation / B cell differentiation / cytokine activity / growth factor activity / positive regulation of cell growth / inflammatory response / positive regulation of cell population proliferation / extracellular space / extracellular region Similarity search - Function | ||||||
Biological species | Homo sapiens (human) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 3.34 Å | ||||||
Authors | De Vos, T. / Savvides, S.N. | ||||||
Funding support | Belgium, 1items
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Citation | Journal: Biorxiv / Year: 2022 Title: Structural basis for the mechanism and antagonism of receptor signaling mediated by Interleukin-9 (IL-9) Authors: De Vos, T. / Godar, M. / Bick, F. / Papageorgiou, A.C. / Evangelidis, T. / Markovic, I. / Mortier, E. / Dumoutier, L. / Tripsianes, K. / Blanchetot, C. / Savvides, S.N. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 7ox2.cif.gz | 745.2 KB | Display | PDBx/mmCIF format |
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PDB format | pdb7ox2.ent.gz | 624.8 KB | Display | PDB format |
PDBx/mmJSON format | 7ox2.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/ox/7ox2 ftp://data.pdbj.org/pub/pdb/validation_reports/ox/7ox2 | HTTPS FTP |
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-Related structure data
Related structure data | 7ox1C 7ox3C 7ox4C 7ox5C 7ox6C 5y9jS 6ghgS S: Starting model for refinement C: citing same article (ref.) |
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Similar structure data | Similarity search - Function & homologyF&H Search |
-Links
-Assembly
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
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