登録情報 | データベース: PDB / ID: 7br9 |
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タイトル | Crystal structure of mus musculus IRG1 |
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要素 | Cis-aconitate decarboxylase |
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キーワード | STRUCTURAL PROTEIN / IRG1 / cis-Aconitate decarboxylase / Immune-responsive gene 1 protein |
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機能・相同性 | 機能・相同性情報
cis-aconitate decarboxylase / positive regulation of antimicrobial humoral response / aconitate decarboxylase activity / tolerance induction to lipopolysaccharide / cellular response to molecule of bacterial origin / negative regulation of toll-like receptor 2 signaling pathway / negative regulation of toll-like receptor 4 signaling pathway / cellular response to progesterone stimulus / negative regulation of type I interferon production / negative regulation of NF-kappaB transcription factor activity ...cis-aconitate decarboxylase / positive regulation of antimicrobial humoral response / aconitate decarboxylase activity / tolerance induction to lipopolysaccharide / cellular response to molecule of bacterial origin / negative regulation of toll-like receptor 2 signaling pathway / negative regulation of toll-like receptor 4 signaling pathway / cellular response to progesterone stimulus / negative regulation of type I interferon production / negative regulation of NF-kappaB transcription factor activity / cellular response to interferon-beta / cellular response to interleukin-1 / negative regulation of innate immune response / embryo implantation / response to bacterium / defense response / negative regulation of inflammatory response / cellular response to type II interferon / positive regulation of reactive oxygen species metabolic process / cellular response to tumor necrosis factor / cellular response to lipopolysaccharide / defense response to virus / response to lipopolysaccharide / inflammatory response / protein homodimerization activity / mitochondrion類似検索 - 分子機能 MmgE/PrpD, N-terminal / MmgE/PrpD, C-terminal / MmgE/PrpD / MmgE/PrpD superfamily / MmgE/PrpD superfamily, domain 1 / MmgE/PrpD superfamily, domain 2 / MmgE/PrpD N-terminal domain / MmgE/PrpD C-terminal domain類似検索 - ドメイン・相同性 Cis-aconitate decarboxylase / Cis-aconitate decarboxylase類似検索 - 構成要素 |
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生物種 | Mus musculus (ハツカネズミ) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 3.3 Å |
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データ登録者 | Park, H.H. / Chun, H.L. |
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資金援助 | 韓国, 1件 組織 | 認可番号 | 国 |
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National Research Foundation (NRF, Korea) | | 韓国 |
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引用 | ジャーナル: Plos One / 年: 2020 タイトル: The crystal structure of mouse IRG1 suggests that cis-aconitate decarboxylase has an open and closed conformation. 著者: Chun, H.L. / Lee, S.Y. / Kim, K.H. / Lee, C.S. / Oh, T.J. / Park, H.H. |
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履歴 | 登録 | 2020年3月27日 | 登録サイト: PDBJ / 処理サイト: PDBJ |
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改定 1.0 | 2021年2月3日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2023年11月29日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Refinement description カテゴリ: atom_type / chem_comp_atom ...atom_type / chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _atom_type.pdbx_N_electrons / _atom_type.pdbx_scat_Z ..._atom_type.pdbx_N_electrons / _atom_type.pdbx_scat_Z / _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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