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Yorodumi- PDB-7ac8: Molecular basis for the unique allosteric activation mechanism of... -
+Open data
-Basic information
Entry | Database: PDB / ID: 7ac8 | ||||||
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Title | Molecular basis for the unique allosteric activation mechanism of the heterodimeric imidazole glycerol phosphate synthase complex. | ||||||
Components | (Imidazole glycerol phosphate synthase subunit ...) x 2 | ||||||
Keywords | LYASE / Enzyme regulation / Allostery / Ensemble model / conformational changes / HisF / HisH / Imidazole Glycerol Phosphate Synthase / LYASE (4.3.2.10) | ||||||
Function / homology | Function and homology information imidazole glycerol-phosphate synthase / imidazoleglycerol-phosphate synthase activity / glutaminase / L-histidine biosynthetic process / glutaminase activity / glutamine metabolic process / amino acid biosynthetic process / lyase activity / cytoplasm Similarity search - Function | ||||||
Biological species | Thermotoga maritima (bacteria) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.06 Å | ||||||
Authors | Sung, S. / Wilmanns, M. | ||||||
Funding support | European Union, 1items
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Citation | Journal: Nat Commun / Year: 2021 Title: Molecular basis for the allosteric activation mechanism of the heterodimeric imidazole glycerol phosphate synthase complex. Authors: Wurm, J.P. / Sung, S. / Kneuttinger, A.C. / Hupfeld, E. / Sterner, R. / Wilmanns, M. / Sprangers, R. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 7ac8.cif.gz | 555.3 KB | Display | PDBx/mmCIF format |
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PDB format | pdb7ac8.ent.gz | 455.5 KB | Display | PDB format |
PDBx/mmJSON format | 7ac8.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 7ac8_validation.pdf.gz | 1.5 MB | Display | wwPDB validaton report |
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Full document | 7ac8_full_validation.pdf.gz | 1.5 MB | Display | |
Data in XML | 7ac8_validation.xml.gz | 55.6 KB | Display | |
Data in CIF | 7ac8_validation.cif.gz | 77.9 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/ac/7ac8 ftp://data.pdbj.org/pub/pdb/validation_reports/ac/7ac8 | HTTPS FTP |
-Related structure data
Related structure data | 1gpwS S: Starting model for refinement |
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Similar structure data |
-Links
-Assembly
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments:
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