Entry | Database: PDB / ID: 6we7 |
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Title | HIV Integrase core domain in complex with inhibitor 3-methyl-2-{5-methyl-2-[2-(thiophen-2-yl)ethynyl]-1- benzofuran-3-yl}butanoic acid |
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Components | Integrase |
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Keywords | TRANSFERASE/TRANSFERASE INHIBITOR / Inhibitor / HIV Integrase / TRANSFERASE-TRANSFERASE INHIBITOR complex |
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Function / homology | Function and homology information
DNA integration / RNA stem-loop binding / RNA-directed DNA polymerase activity / endonuclease activity / DNA recombination / symbiont entry into host cell / zinc ion bindingSimilarity search - Function Integrase Zinc binding domain / Zinc finger integrase-type profile. / Integrase-like, N-terminal / Integrase DNA binding domain / Integrase, C-terminal domain superfamily, retroviral / Integrase, N-terminal zinc-binding domain / Integrase, C-terminal, retroviral / Integrase DNA binding domain profile. / Integrase core domain / Integrase, catalytic core ...Integrase Zinc binding domain / Zinc finger integrase-type profile. / Integrase-like, N-terminal / Integrase DNA binding domain / Integrase, C-terminal domain superfamily, retroviral / Integrase, N-terminal zinc-binding domain / Integrase, C-terminal, retroviral / Integrase DNA binding domain profile. / Integrase core domain / Integrase, catalytic core / Integrase catalytic domain profile. / Ribonuclease H superfamily / Ribonuclease H-like superfamilySimilarity search - Domain/homology |
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Biological species | ![](img/tx_virus.gif) Human immunodeficiency virus 1 |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / FOURIER SYNTHESIS / Resolution: 2.28 Å |
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Authors | Gorman, M.A. / Parker, M.W. |
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Citation | Journal: To Be Published Title: HIV Integrase core domain in complex with inhibitor Authors: Gorman, M.A. / Parker, M.W. |
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History | Deposition | Apr 1, 2020 | Deposition site: RCSB / Processing site: RCSB |
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Revision 1.0 | Apr 7, 2021 | Provider: repository / Type: Initial release |
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