Entry | Database: PDB / ID: 6pki |
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Title | Zebrafish N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (NAGPA) catalytic domain (C56S C230S) in complex with N-acetyl-alpha-D-glucosamine (alpha-GlcNAc) and mannose 6-phosphate (M6P) |
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Components | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase |
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Keywords | HYDROLASE / uncovering enzyme / mannose 6-phosphate / glycosidase / n-acetylglucosamine |
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Function / homology | Function and homology information
Phosphodiester glycosidase / Phosphodiester glycosidase / Laminin-type EGF domain / EGF-like domain, extracellular / EGF-like domain / Epidermal growth factor-like domain. / EGF-like domain profile. / EGF-like domain signature 1. / EGF-like domainSimilarity search - Domain/homology 6-O-phosphono-alpha-D-mannopyranose / 2-acetamido-2-deoxy-alpha-D-glucopyranose / N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidaseSimilarity search - Component |
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Biological species | ![](img/tx_fish.gif) Danio rerio (zebrafish) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.293 Å |
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Authors | Gorelik, A. / Illes, K. / Nagar, B. |
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Funding support | Canada, 1items Organization | Grant number | Country |
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Canadian Institutes of Health Research (CIHR) | MOP-133535 | Canada |
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Citation | Journal: Structure / Year: 2020 Title: Crystal Structure of the Mannose-6-Phosphate Uncovering Enzyme. Authors: Gorelik, A. / Illes, K. / Nagar, B. |
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History | Deposition | Jun 29, 2019 | Deposition site: RCSB / Processing site: RCSB |
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Revision 1.0 | Feb 19, 2020 | Provider: repository / Type: Initial release |
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Revision 1.1 | Mar 11, 2020 | Group: Database references / Category: citation Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_ASTM / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year |
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Revision 1.2 | Apr 15, 2020 | Group: Database references / Category: citation Item: _citation.journal_volume / _citation.page_first / _citation.page_last |
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Revision 2.0 | Jul 29, 2020 | Group: Atomic model / Data collection ...Atomic model / Data collection / Derived calculations / Structure summary Category: atom_site / chem_comp ...atom_site / chem_comp / entity / pdbx_chem_comp_identifier / pdbx_entity_nonpoly / struct_conn / struct_site / struct_site_gen Item: _atom_site.auth_atom_id / _atom_site.label_atom_id ..._atom_site.auth_atom_id / _atom_site.label_atom_id / _chem_comp.mon_nstd_flag / _chem_comp.name / _chem_comp.type / _entity.pdbx_description / _pdbx_entity_nonpoly.name / _struct_conn.pdbx_role Description: Carbohydrate remediation / Provider: repository / Type: Remediation |
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Revision 2.1 | Oct 11, 2023 | Group: Data collection / Database references ...Data collection / Database references / Refinement description / Structure summary Category: chem_comp / chem_comp_atom ...chem_comp / chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _chem_comp.pdbx_synonyms / _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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