Entry | Database: PDB / ID: 6pbd |
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Title | DNA N6-Adenine Methyltransferase CcrM In Complex with Double-Stranded DNA Oligonucleotide Containing Its Recognition Sequence GAATC |
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Components | - DNA (5'-D(*CP*GP*AP*TP*TP*CP*AP*AP*TP*GP*AP*AP*TP*CP*CP*CP*AP*AP*G)-3')
- DNA (5'-D(*GP*CP*TP*TP*GP*GP*GP*AP*TP*TP*CP*AP*TP*TP*GP*AP*AP*TP*C)-3')
- Modification methylase CcrMI
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Keywords | TRANSFERASE/DNA / DNA methylation / GANTC recognition / base flipping / TRANSFERASE-DNA complex |
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Function / homology | Function and homology information
N-methyltransferase activity / site-specific DNA-methyltransferase (adenine-specific) / site-specific DNA-methyltransferase (adenine-specific) activity / DNA replication / DNA bindingSimilarity search - Function Restriction enzyme adenine methylase associated / Restriction Enzyme Adenine Methylase Associated / Restriction/modification DNA-methyltransferase / DNA methylase N-4/N-6 / DNA methylase / N-6 Adenine-specific DNA methylases signature. / DNA methylase, N-6 adenine-specific, conserved site / S-adenosyl-L-methionine-dependent methyltransferase superfamilySimilarity search - Domain/homology |
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Biological species | Caulobacter vibrioides (bacteria) synthetic construct (others) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.343 Å |
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Authors | Horton, J.R. / Cheng, X. / Woodcock, C.B. |
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Funding support | United States, 1items Organization | Grant number | Country |
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National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | GM049245-23 | United States |
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Citation | Journal: Nat Commun / Year: 2019 Title: The cell cycle-regulated DNA adenine methyltransferase CcrM opens a bubble at its DNA recognition site. Authors: Horton, J.R. / Woodcock, C.B. / Opot, S.B. / Reich, N.O. / Zhang, X. / Cheng, X. |
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History | Deposition | Jun 13, 2019 | Deposition site: RCSB / Processing site: RCSB |
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Revision 1.0 | Oct 23, 2019 | Provider: repository / Type: Initial release |
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Revision 1.1 | Jan 1, 2020 | Group: Author supporting evidence / Category: pdbx_audit_support / Item: _pdbx_audit_support.funding_organization |
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Revision 1.2 | Oct 11, 2023 | Group: Data collection / Database references / Refinement description Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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