- PDB-6oqm: crystal structure of the MSH6 PWWP domain -
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基本情報
登録情報
データベース: PDB / ID: 6oqm
タイトル
crystal structure of the MSH6 PWWP domain
要素
DNA mismatch repair protein Msh6
キーワード
DNA BINDING PROTEIN / PWWP domain / Structural Genomics / Structural Genomics Consortium / SGC
機能・相同性
機能・相同性情報
MutSalpha complex / Defective Mismatch Repair Associated With MSH2 / Defective Mismatch Repair Associated With MSH6 / guanine/thymine mispair binding / somatic recombination of immunoglobulin gene segments / positive regulation of helicase activity / meiotic mismatch repair / mismatched DNA binding / negative regulation of DNA recombination / isotype switching ...MutSalpha complex / Defective Mismatch Repair Associated With MSH2 / Defective Mismatch Repair Associated With MSH6 / guanine/thymine mispair binding / somatic recombination of immunoglobulin gene segments / positive regulation of helicase activity / meiotic mismatch repair / mismatched DNA binding / negative regulation of DNA recombination / isotype switching / Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) / ATP-dependent DNA damage sensor activity / somatic hypermutation of immunoglobulin genes / ATP-dependent activity, acting on DNA / mismatch repair / response to UV / methylated histone binding / intrinsic apoptotic signaling pathway / determination of adult lifespan / intrinsic apoptotic signaling pathway in response to DNA damage / spermatogenesis / damaged DNA binding / intracellular membrane-bounded organelle / DNA repair / chromatin binding / chromatin / Golgi apparatus / enzyme binding / nucleoplasm / ATP binding / nucleus / cytosol 類似検索 - 分子機能
DNA mismatch repair protein MutS/MSH / DNA mismatch repair protein MutS-like, N-terminal / DNA mismatch repair protein MutS, connector domain / DNA mismatch repair protein MutS, clamp / DNA mismatch repair protein MutS, N-terminal / MutS, connector domain superfamily / MutS domain I / MutS domain II / MutS family domain IV / MutS domain III ...DNA mismatch repair protein MutS/MSH / DNA mismatch repair protein MutS-like, N-terminal / DNA mismatch repair protein MutS, connector domain / DNA mismatch repair protein MutS, clamp / DNA mismatch repair protein MutS, N-terminal / MutS, connector domain superfamily / MutS domain I / MutS domain II / MutS family domain IV / MutS domain III / DNA mismatch repair MutS family / DNA mismatch repair protein MutS, C-terminal / DNA mismatch repair protein MutS, core / DNA mismatch repair protein MutS, core domain superfamily / MutS domain V / DNA mismatch repair proteins mutS family signature. / DNA-binding domain of DNA mismatch repair MUTS family / ATPase domain of DNA mismatch repair MUTS family / domain with conserved PWWP motif / PWWP domain / PWWP domain profile. / PWWP domain / P-loop containing nucleoside triphosphate hydrolase 類似検索 - ドメイン・相同性