登録情報 | データベース: PDB / ID: 6opf |
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タイトル | Crystal structure of dmNxf2 UBA domain fused with Panoramix helix |
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要素 | Nuclear RNA export factor 2, Panoramix fusion |
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キーワード | RNA BINDING PROTEIN / Piwi / transposon silencing / heterochromatin formation / piRNA pathway / transcriptional silencing |
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機能・相同性 | 機能・相同性情報
Transport of Mature mRNA derived from an Intron-Containing Transcript / piRNA-mediated heterochromatin formation / piRNA-mediated retrotransposon silencing by heterochromatin formation / piRNA binding / positive regulation of DNA methylation-dependent heterochromatin formation / poly(A)+ mRNA export from nucleus / transcription repressor complex / single-stranded RNA binding / negative regulation of gene expression / RNA binding ...Transport of Mature mRNA derived from an Intron-Containing Transcript / piRNA-mediated heterochromatin formation / piRNA-mediated retrotransposon silencing by heterochromatin formation / piRNA binding / positive regulation of DNA methylation-dependent heterochromatin formation / poly(A)+ mRNA export from nucleus / transcription repressor complex / single-stranded RNA binding / negative regulation of gene expression / RNA binding / nucleoplasm / nucleus / cytoplasm類似検索 - 分子機能 TAP C-terminal (TAP-C) domain / TAP C-terminal domain / TAP C-terminal (TAP-C) domain profile. / C-terminal domain of vertebrate Tap protein / Nuclear RNA export factor / Nuclear transport factor 2, eukaryote / Nuclear transport factor 2 domain profile. / UBA-like superfamily / NTF2-like domain superfamily / Leucine-rich repeat profile. ...TAP C-terminal (TAP-C) domain / TAP C-terminal domain / TAP C-terminal (TAP-C) domain profile. / C-terminal domain of vertebrate Tap protein / Nuclear RNA export factor / Nuclear transport factor 2, eukaryote / Nuclear transport factor 2 domain profile. / UBA-like superfamily / NTF2-like domain superfamily / Leucine-rich repeat profile. / Leucine-rich repeat / Leucine-rich repeat domain superfamily類似検索 - ドメイン・相同性 Nuclear RNA export factor 2 / Protein panoramix類似検索 - 構成要素 |
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生物種 | Drosophila melanogaster (キイロショウジョウバエ) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2 Å |
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データ登録者 | Wang, J. / Patel, D.J. |
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資金援助 | 米国, 3件 組織 | 認可番号 | 国 |
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National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | P30 GM124165 | 米国 | Department of Energy (DOE, United States) | DE-AC02-06CH11357 | 米国 | National Institutes of Health/National Cancer Institute (NIH/NCI) | P30 CA008748 | 米国 |
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引用 | ジャーナル: Nat.Struct.Mol.Biol. / 年: 2019 タイトル: The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation. 著者: Batki, J. / Schnabl, J. / Wang, J. / Handler, D. / Andreev, V.I. / Stieger, C.E. / Novatchkova, M. / Lampersberger, L. / Kauneckaite, K. / Xie, W. / Mechtler, K. / Patel, D.J. / Brennecke, J. |
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履歴 | 登録 | 2019年4月24日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2019年7月3日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2019年8月7日 | Group: Data collection / Database references / カテゴリ: citation / citation_author Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.pdbx_database_id_DOI / _citation.year / _citation_author.name |
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改定 1.2 | 2019年8月21日 | Group: Data collection / Database references / カテゴリ: citation / citation_author Item: _citation.journal_volume / _citation.page_first ..._citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_PubMed / _citation.title |
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改定 1.3 | 2019年12月4日 | Group: Author supporting evidence / カテゴリ: pdbx_audit_support / Item: _pdbx_audit_support.funding_organization |
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改定 1.4 | 2023年10月11日 | Group: Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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