- PDB-6o6h: RIAM cc-RA-PH structure in the P21212 space group -
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Open data
ID or keywords:
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Basic information
Entry
Database: PDB / ID: 6o6h
Title
RIAM cc-RA-PH structure in the P21212 space group
Components
Amyloid beta A4 precursor protein-binding family B member 1-interacting protein
Keywords
SIGNALING PROTEIN / RAP1 Effector RA-PH
Function / homology
Function and homology information
GRB2:SOS provides linkage to MAPK signaling for Integrins / T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell / Integrin signaling / p130Cas linkage to MAPK signaling for integrins / MAP2K and MAPK activation / T cell receptor complex / positive regulation of cell adhesion / lamellipodium / cytoskeleton / focal adhesion ...GRB2:SOS provides linkage to MAPK signaling for Integrins / T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell / Integrin signaling / p130Cas linkage to MAPK signaling for integrins / MAP2K and MAPK activation / T cell receptor complex / positive regulation of cell adhesion / lamellipodium / cytoskeleton / focal adhesion / signal transduction / plasma membrane / cytosol Similarity search - Function
Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray
Radiation wavelength
Wavelength: 0.9775 Å / Relative weight: 1
Reflection
Resolution: 2.5→62.39 Å / Num. obs: 12656 / % possible obs: 100 % / Redundancy: 6.2 % / Net I/σ(I): 20.5
Reflection shell
Resolution: 2.5→2.54 Å / Redundancy: 6.3 % / Num. unique obs: 603 / % possible all: 100
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Processing
Software
Name
Version
Classification
REFMAC
5.8.0135
refinement
HKL-2000
datareduction
HKL-2000
datascaling
PHASER
phasing
Refinement
Method to determine structure: MOLECULAR REPLACEMENT / Resolution: 2.5→62.39 Å / Cor.coef. Fo:Fc: 0.931 / Cor.coef. Fo:Fc free: 0.889 / SU B: 19.26 / SU ML: 0.21 / Cross valid method: THROUGHOUT / ESU R: 0.463 / ESU R Free: 0.303 / Details: HYDROGENS HAVE BEEN USED IF PRESENT IN THE INPUT
Rfactor
Num. reflection
% reflection
Selection details
Rfree
0.28092
610
4.9 %
RANDOM
Rwork
0.22886
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obs
0.23129
11895
99.77 %
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Solvent computation
Ion probe radii: 0.8 Å / Shrinkage radii: 0.8 Å / VDW probe radii: 1.2 Å