positive regulation of natural killer cell mediated immune response to tumor cell / activating MHC class I receptor activity / negative regulation of CD4-positive, alpha-beta T cell costimulation / negative regulation of adaptive immune memory response / positive regulation of natural killer cell degranulation / MHC class I protein complex binding / mucosal immune response / MHC class Ib receptor activity / positive regulation of natural killer cell cytokine production / MHC class I receptor activity ...positive regulation of natural killer cell mediated immune response to tumor cell / activating MHC class I receptor activity / negative regulation of CD4-positive, alpha-beta T cell costimulation / negative regulation of adaptive immune memory response / positive regulation of natural killer cell degranulation / MHC class I protein complex binding / mucosal immune response / MHC class Ib receptor activity / positive regulation of natural killer cell cytokine production / MHC class I receptor activity / positive regulation of natural killer cell mediated cytotoxicity / positive regulation of endothelial cell apoptotic process / negative regulation of T cell receptor signaling pathway / side of membrane / T cell costimulation / negative regulation of angiogenesis / phosphatidylinositol 3-kinase/protein kinase B signal transduction / kinase binding / Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell / positive regulation of type II interferon production / angiogenesis / defense response to Gram-negative bacterium / adaptive immune response / innate immune response / signaling receptor binding / extracellular region / plasma membrane Similarity search - Function
Resolution: 1.954→35 Å / Cor.coef. Fo:Fc: 0.95 / Cor.coef. Fo:Fc free: 0.931 / SU B: 4.463 / SU ML: 0.127 / Cross valid method: THROUGHOUT / ESU R: 0.185 / ESU R Free: 0.171 / Details: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS
Rfactor
Num. reflection
% reflection
Selection details
Rfree
0.2533
789
4.8 %
RANDOM
Rwork
0.20219
-
-
-
obs
0.20465
15683
99.81 %
-
Solvent computation
Ion probe radii: 0.8 Å / Shrinkage radii: 0.8 Å / VDW probe radii: 1.2 Å