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Yorodumi- PDB-6mcp: L. pneumophila effector kinase LegK7 (AMP-PNP bound) in complex w... -
+Open data
-Basic information
Entry | Database: PDB / ID: 6mcp | ||||||
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Title | L. pneumophila effector kinase LegK7 (AMP-PNP bound) in complex with human MOB1A | ||||||
Components |
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Keywords | TRANSFERASE / translocated effector / Ser/Thr protein kinase / allosteric activation / Hippo pathway | ||||||
Function / homology | Function and homology information hippo signaling / Signaling by Hippo / protein kinase activator activity / protein serine/threonine kinase activator activity / positive regulation of protein phosphorylation / extracellular exosome / nucleus / metal ion binding / cytoplasm / cytosol Similarity search - Function | ||||||
Biological species | Legionella pneumophila subsp. pneumophila (bacteria) Homo sapiens (human) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.5 Å | ||||||
Authors | Beyrakhova, K.A. / Xu, C. / Boniecki, M.T. / Cygler, M. | ||||||
Funding support | Canada, 1items
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Citation | Journal: Proc.Natl.Acad.Sci.USA / Year: 2020 Title: TheLegionellakinase LegK7 exploits the Hippo pathway scaffold protein MOB1A for allostery and substrate phosphorylation. Authors: Lee, P.C. / Beyrakhova, K. / Xu, C. / Boniecki, M.T. / Lee, M.H. / Onu, C.J. / Grishin, A.M. / Machner, M.P. / Cygler, M. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 6mcp.cif.gz | 580.9 KB | Display | PDBx/mmCIF format |
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PDB format | pdb6mcp.ent.gz | 475 KB | Display | PDB format |
PDBx/mmJSON format | 6mcp.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 6mcp_validation.pdf.gz | 1.7 MB | Display | wwPDB validaton report |
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Full document | 6mcp_full_validation.pdf.gz | 1.7 MB | Display | |
Data in XML | 6mcp_validation.xml.gz | 53.1 KB | Display | |
Data in CIF | 6mcp_validation.cif.gz | 70.3 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/mc/6mcp ftp://data.pdbj.org/pub/pdb/validation_reports/mc/6mcp | HTTPS FTP |
-Related structure data
Related structure data | 6mcqSC S: Starting model for refinement C: citing same article (ref.) |
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Similar structure data |
-Links
-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments:
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