登録情報 | データベース: PDB / ID: 6k18 |
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タイトル | Crystal structure of EXD2 exonuclease domain soaked in Mn |
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要素 | Exonuclease 3'-5' domain-containing protein 2 |
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キーワード | HYDROLASE / 3'-5' exonuclease / DnaQ family |
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機能・相同性 | 機能・相同性情報
exodeoxyribonuclease I / nucleic acid metabolic process / DNA double-strand break processing / single-stranded DNA 3'-5' DNA exonuclease activity / intermediate filament cytoskeleton / 3'-5'-DNA exonuclease activity / replication fork processing / site of DNA damage / 3'-5' exonuclease activity / double-strand break repair via homologous recombination ...exodeoxyribonuclease I / nucleic acid metabolic process / DNA double-strand break processing / single-stranded DNA 3'-5' DNA exonuclease activity / intermediate filament cytoskeleton / 3'-5'-DNA exonuclease activity / replication fork processing / site of DNA damage / 3'-5' exonuclease activity / double-strand break repair via homologous recombination / double-strand break repair / manganese ion binding / 加水分解酵素; エステル加水分解酵素; 5'-リン酸モノエステル産生エキソリボヌクレアーゼ / 3'-5'-RNA exonuclease activity / mitochondrial outer membrane / nucleic acid binding / mitochondrial matrix / magnesium ion binding / protein homodimerization activity / mitochondrion / nucleus / cytoplasm類似検索 - 分子機能 3'-5' exonuclease / 3'-5' exonuclease / 3'-5' exonuclease domain / Ribonuclease H superfamily / Ribonuclease H-like superfamily類似検索 - ドメイン・相同性 : / Exonuclease 3'-5' domain-containing protein 2類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.303 Å |
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データ登録者 | Park, J. / Lee, C. |
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引用 | ジャーナル: Nucleic Acids Res. / 年: 2019 タイトル: The structure of human EXD2 reveals a chimeric 3' to 5' exonuclease domain that discriminates substrates via metal coordination. 著者: Park, J. / Lee, S.Y. / Jeong, H. / Kang, M.G. / Van Haute, L. / Minczuk, M. / Seo, J.K. / Jun, Y. / Myung, K. / Rhee, H.W. / Lee, C. |
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履歴 | 登録 | 2019年5月10日 | 登録サイト: PDBJ / 処理サイト: PDBJ |
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改定 1.0 | 2019年5月22日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2019年12月4日 | Group: Database references / カテゴリ: citation / citation_author Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_ASTM / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year |
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改定 1.2 | 2023年11月22日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / pdbx_struct_conn_angle / struct_conn Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_conn_angle.ptnr1_auth_asym_id / _pdbx_struct_conn_angle.ptnr1_auth_comp_id / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_asym_id / _pdbx_struct_conn_angle.ptnr1_label_atom_id / _pdbx_struct_conn_angle.ptnr1_label_comp_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr3_auth_asym_id / _pdbx_struct_conn_angle.ptnr3_auth_comp_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_label_asym_id / _pdbx_struct_conn_angle.ptnr3_label_atom_id / _pdbx_struct_conn_angle.ptnr3_label_comp_id / _pdbx_struct_conn_angle.ptnr3_label_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id |
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