+Open data
-Basic information
Entry | Database: PDB / ID: 6ilh | |||||||||
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Title | Crystal Structure of human lysyl-tRNA synthetase L350H mutant | |||||||||
Components | Lysine-tRNA ligase | |||||||||
Keywords | LIGASE / lysyl-tRNA synthetase / LysRS / disease related mutant | |||||||||
Function / homology | Function and homology information basophil activation involved in immune response / positive regulation of inflammatory response to antigenic stimulus / Mitochondrial tRNA aminoacylation / ATP:ADP adenylyltransferase activity / lysine-tRNA ligase / Selenoamino acid metabolism / lysine-tRNA ligase activity / lysyl-tRNA aminoacylation / diadenosine tetraphosphate biosynthetic process / Cytosolic tRNA aminoacylation ...basophil activation involved in immune response / positive regulation of inflammatory response to antigenic stimulus / Mitochondrial tRNA aminoacylation / ATP:ADP adenylyltransferase activity / lysine-tRNA ligase / Selenoamino acid metabolism / lysine-tRNA ligase activity / lysyl-tRNA aminoacylation / diadenosine tetraphosphate biosynthetic process / Cytosolic tRNA aminoacylation / aminoacyl-tRNA synthetase multienzyme complex / positive regulation of macrophage activation / tRNA processing / amino acid binding / response to X-ray / ERK1 and ERK2 cascade / Transferases; Transferring phosphorus-containing groups; Nucleotidyltransferases / tRNA binding / mitochondrial matrix / positive regulation of DNA-templated transcription / protein homodimerization activity / mitochondrion / extracellular space / ATP binding / identical protein binding / nucleus / plasma membrane / cytosol Similarity search - Function | |||||||||
Biological species | Homo sapiens (human) | |||||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.501 Å | |||||||||
Authors | Hei, Z. / Liu, Z. / Wang, J. / Fang, P. | |||||||||
Funding support | China, 2items
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Citation | Journal: J. Biol. Chem. / Year: 2019 Title: Retractile lysyl-tRNA synthetase-AIMP2 assembly in the human multi-aminoacyl-tRNA synthetase complex. Authors: Hei, Z. / Wu, S. / Liu, Z. / Wang, J. / Fang, P. | |||||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 6ilh.cif.gz | 409.7 KB | Display | PDBx/mmCIF format |
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PDB format | pdb6ilh.ent.gz | 331.6 KB | Display | PDB format |
PDBx/mmJSON format | 6ilh.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 6ilh_validation.pdf.gz | 911.1 KB | Display | wwPDB validaton report |
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Full document | 6ilh_full_validation.pdf.gz | 924.4 KB | Display | |
Data in XML | 6ilh_validation.xml.gz | 37 KB | Display | |
Data in CIF | 6ilh_validation.cif.gz | 49.9 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/il/6ilh ftp://data.pdbj.org/pub/pdb/validation_reports/il/6ilh | HTTPS FTP |
-Related structure data
Related structure data | 6ildC 3bjuS C: citing same article (ref.) S: Starting model for refinement |
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Similar structure data |
-Links
-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Ens-ID: 1
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