登録情報 データベース : PDB / ID : 6iiv 構造の表示 ダウンロードとリンクタイトル Crystal structure of the human thromboxane A2 receptor bound to daltroban 要素Soluble cytochrome b562,Thromboxane A2 receptor,Rubredoxin,Thromboxane A2 receptor 詳細 キーワード SIGNALING PROTEIN / GPCR / Complex / Antagonist機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
thromboxane A2 receptor activity / Prostanoid ligand receptors / alkane catabolic process / positive regulation of smooth muscle contraction / positive regulation of blood pressure / negative regulation of cell migration involved in sprouting angiogenesis / response to testosterone / smooth muscle contraction / positive regulation of blood coagulation / positive regulation of vasoconstriction ... thromboxane A2 receptor activity / Prostanoid ligand receptors / alkane catabolic process / positive regulation of smooth muscle contraction / positive regulation of blood pressure / negative regulation of cell migration involved in sprouting angiogenesis / response to testosterone / smooth muscle contraction / positive regulation of blood coagulation / positive regulation of vasoconstriction / response to nutrient / guanyl-nucleotide exchange factor activity / acrosomal vesicle / electron transport chain / Thromboxane signalling through TP receptor / adenylate cyclase-activating G protein-coupled receptor signaling pathway / positive regulation of angiogenesis / G alpha (12/13) signalling events / positive regulation of cytosolic calcium ion concentration / G alpha (q) signalling events / cellular response to lipopolysaccharide / response to ethanol / periplasmic space / electron transfer activity / nuclear speck / response to xenobiotic stimulus / inflammatory response / iron ion binding / G protein-coupled receptor signaling pathway / heme binding / plasma membrane 類似検索 - 分子機能 Thromboxane receptor / Prostanoid receptor / Rubredoxin / Rubredoxin, iron-binding site / Rubredoxin signature. / Rubredoxin domain / Rubredoxin / Rubredoxin-like domain / Rubredoxin-like domain profile. / Cytochrome b562 ... Thromboxane receptor / Prostanoid receptor / Rubredoxin / Rubredoxin, iron-binding site / Rubredoxin signature. / Rubredoxin domain / Rubredoxin / Rubredoxin-like domain / Rubredoxin-like domain profile. / Cytochrome b562 / Cytochrome b562 / Cytochrome c/b562 / G-protein coupled receptors family 1 signature. / G protein-coupled receptor, rhodopsin-like / GPCR, rhodopsin-like, 7TM / G-protein coupled receptors family 1 profile. / 7 transmembrane receptor (rhodopsin family) 類似検索 - ドメイン・相同性 Chem-A90 / CHOLESTEROL / Rubredoxin / Soluble cytochrome b562 / Thromboxane A2 receptor 類似検索 - 構成要素生物種 Escherichia coli (大腸菌)Homo sapiens (ヒト)Clostridium pasteurianum (バクテリア)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 3 Å 詳細データ登録者 Fan, H. / Zhao, Q. / Wu, B. 資金援助 中国, 1件 詳細 詳細を隠す組織 認可番号 国 Chinese Academy of Sciences QYZDB-SSW-SMC024 中国
引用ジャーナル : Nat. Chem. Biol. / 年 : 2019タイトル : Structural basis for ligand recognition of the human thromboxane A2receptor.著者 : Fan, H. / Chen, S. / Yuan, X. / Han, S. / Zhang, H. / Xia, W. / Xu, Y. / Zhao, Q. / Wu, B. 履歴 登録 2018年10月7日 登録サイト : PDBJ / 処理サイト : PDBJ改定 1.0 2018年12月19日 Provider : repository / タイプ : Initial release改定 1.1 2018年12月26日 Group : Data collection / Database references / カテゴリ : citationItem : _citation.journal_volume / _citation.page_first ... _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.year 改定 1.2 2023年11月22日 Group : Data collection / Database references / Refinement descriptionカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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