Entry | Database: PDB / ID: 6h49 |
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Title | A polyamorous repressor: deciphering the evolutionary strategy used by the phage-inducible chromosomal islands to spread in nature. |
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Components | Orf20 |
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Keywords | STRUCTURAL PROTEIN / SaPI / Repressor |
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Function / homology | Helix-turn-helix / Helix-turn-helix XRE-family like proteins / Cro/C1-type HTH domain profile. / Cro/C1-type helix-turn-helix domain / Lambda repressor-like, DNA-binding domain superfamily / DNA binding / Orf20 Function and homology information |
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Biological species | ![](img/tx_bacteria.gif) Staphylococcus aureus (bacteria) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 1.8 Å |
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Authors | Ciges-Tomas, J.R. / Alite, C. / Bowring, J.Z. / Donderis, J. / Penades, J.R. / Marina, A. |
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Funding support | Spain, United Kingdom, 6items Organization | Grant number | Country |
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Spanish Ministry of Economy and Competitiveness | BIO2016-78571-P | Spain | Spanish Ministry of Economy and Competitiveness | FPU13/02880 | Spain | Spanish Ministry of Economy and Competitiveness | BES-2014-068617 | Spain | Medical Research Council (United Kingdom) | MR/M003876/1 | United Kingdom | Biotechnology and Biological Sciences Research Council | BB/N002873/1 | United Kingdom | European Research Council | ERC-ADG/2014 670932 | United Kingdom |
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Citation | Journal: Nat Commun / Year: 2019 Title: The structure of a polygamous repressor reveals how phage-inducible chromosomal islands spread in nature. Authors: Rafael Ciges-Tomas, J. / Alite, C. / Humphrey, S. / Donderis, J. / Bowring, J. / Salvatella, X. / Penades, J.R. / Marina, A. |
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History | Deposition | Jul 20, 2018 | Deposition site: PDBE / Processing site: PDBE |
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Revision 1.0 | Aug 28, 2019 | Provider: repository / Type: Initial release |
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Revision 1.1 | Oct 16, 2019 | Group: Data collection / Derived calculations / Category: reflns_shell / struct_conn / Item: _reflns_shell.d_res_high / _reflns_shell.d_res_low |
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Revision 1.2 | May 15, 2024 | Group: Data collection / Database references / Category: chem_comp_atom / chem_comp_bond / database_2 Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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