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Yorodumi- PDB-6g9r: Murine class I major histocompatibility complex H-2 Db in complex... -
+Open data
-Basic information
Entry | Database: PDB / ID: 6g9r | ||||||
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Title | Murine class I major histocompatibility complex H-2 Db in complex with self-antigen derived from dopamine monooxygenase. | ||||||
Components |
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Keywords | IMMUNE SYSTEM / LCMV / cross-reactivity / MHC class I / TCR / APL | ||||||
Function / homology | Function and homology information regulation of vascular associated smooth muscle cell proliferation / Catecholamine biosynthesis / octopamine metabolic process / dopamine beta-monooxygenase / leukocyte mediated immunity / dopamine beta-monooxygenase activity / octopamine biosynthetic process / homoiothermy / regulation of vascular endothelial cell proliferation / chromaffin granule lumen ...regulation of vascular associated smooth muscle cell proliferation / Catecholamine biosynthesis / octopamine metabolic process / dopamine beta-monooxygenase / leukocyte mediated immunity / dopamine beta-monooxygenase activity / octopamine biosynthetic process / homoiothermy / regulation of vascular endothelial cell proliferation / chromaffin granule lumen / regulation of extrinsic apoptotic signaling pathway / norepinephrine biosynthetic process / varicosity / chromaffin granule membrane / behavioral response to ethanol / maternal behavior / dopamine catabolic process / fear response / vasoconstriction / TAP1 binding / TAP2 binding / positive regulation of antibody-dependent cellular cytotoxicity / regulation of natural killer cell mediated immunity / positive regulation of TRAIL production / L-ascorbic acid binding / antigen processing and presentation of exogenous peptide antigen via MHC class Ib / MHC class Ib protein complex / positive regulation of natural killer cell mediated immunity / positive regulation of natural killer cell cytokine production / natural killer cell tolerance induction / natural killer cell lectin-like receptor binding / negative regulation of natural killer cell activation / cis-Golgi network membrane / positive regulation of natural killer cell activation / Endosomal/Vacuolar pathway / DAP12 interactions / Antigen Presentation: Folding, assembly and peptide loading of class I MHC / ER-Phagosome pathway / DAP12 signaling / negative regulation of natural killer cell mediated cytotoxicity / response to pain / Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell / transport vesicle membrane / positive regulation of interleukin-13 production / leukocyte migration / positive regulation of natural killer cell mediated cytotoxicity / regulation of membrane depolarization / positive regulation of natural killer cell proliferation / associative learning / T cell mediated cytotoxicity directed against tumor cell target / antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent / positive regulation of memory T cell activation / positive regulation of immunoglobulin production / TAP complex binding / centriolar satellite / antigen processing and presentation of exogenous peptide antigen via MHC class I / Golgi medial cisterna / positive regulation of CD8-positive, alpha-beta T cell activation / CD8-positive, alpha-beta T cell activation / positive regulation of interleukin-4 production / positive regulation of CD8-positive, alpha-beta T cell proliferation / CD8 receptor binding / blood vessel remodeling / MHC class I protein binding / cellular defense response / endoplasmic reticulum exit site / beta-2-microglobulin binding / TAP binding / positive regulation of vasoconstriction / protection from natural killer cell mediated cytotoxicity / negative regulation of T cell proliferation / antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent / response to amphetamine / antigen processing and presentation of endogenous peptide antigen via MHC class Ib / detection of bacterium / Neutrophil degranulation / T cell receptor binding / secretory granule membrane / 14-3-3 protein binding / locomotory behavior / lumenal side of endoplasmic reticulum membrane / peptide binding / antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent / cellular response to iron(III) ion / visual learning / negative regulation of forebrain neuron differentiation / peptide antigen assembly with MHC class I protein complex / response to molecule of bacterial origin / regulation of erythrocyte differentiation / regulation of iron ion transport / MHC class I peptide loading complex / terminal bouton / HFE-transferrin receptor complex / T cell mediated cytotoxicity / memory / cellular response to iron ion / antigen processing and presentation of endogenous peptide antigen via MHC class I / positive regulation of T cell cytokine production / MHC class I protein complex / multicellular organismal-level iron ion homeostasis Similarity search - Function | ||||||
Biological species | Mus musculus (house mouse) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.7 Å | ||||||
Authors | Achour, A. / Sandalova, T. / Allerbring, E. | ||||||
Citation | Journal: to be published Title: Structural basis for CD8+ T cells auto-reactivity in LCMV infection Authors: Allerbring, E. / Duru, A.D. / Nygren, P.A. / Sandalova, T. / Achour, A. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 6g9r.cif.gz | 318.2 KB | Display | PDBx/mmCIF format |
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PDB format | pdb6g9r.ent.gz | 260.6 KB | Display | PDB format |
PDBx/mmJSON format | 6g9r.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/g9/6g9r ftp://data.pdbj.org/pub/pdb/validation_reports/g9/6g9r | HTTPS FTP |
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-Related structure data
Related structure data | 6g9qC 1s7uS S: Starting model for refinement C: citing same article (ref.) |
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Similar structure data |
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-Assembly
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Component-ID: 0 / Refine code: 0
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