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- PDB-6fr7: HA1.7 Human T-Cell Receptor specific for Influenza virus epitope ... -
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Open data
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Basic information
Entry | Database: PDB / ID: 6fr7 | ||||||
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Title | HA1.7 Human T-Cell Receptor specific for Influenza virus epitope PKYVKQNTLKLAT presented by Human Leukocyte Antigen HLA-DR0101 | ||||||
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Function / homology | ![]() ![]() ![]() ![]() | ||||||
Biological species | ![]() ![]() | ||||||
Method | ![]() ![]() ![]() | ||||||
![]() | Rizkallah, P.J. / Cole, D.K. | ||||||
![]() | ![]() Title: In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility. Authors: Holland, C.J. / MacLachlan, B.J. / Bianchi, V. / Hesketh, S.J. / Morgan, R. / Vickery, O. / Bulek, A.M. / Fuller, A. / Godkin, A. / Sewell, A.K. / Rizkallah, P.J. / Wells, S. / Cole, D.K. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 193.7 KB | Display | ![]() |
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PDB format | ![]() | 154.8 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Arichive directory | ![]() ![]() | HTTPS FTP |
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-Related structure data
Related structure data | ![]() 6eh4C ![]() 6eh5C ![]() 6eh6C ![]() 6eh7C ![]() 6eh8SC ![]() 6eh9C ![]() 6fr3C ![]() 6fr4C ![]() 6fr5C ![]() 6fr6C ![]() 6fr8C ![]() 6fr9C ![]() 6fraC ![]() 6frbC ![]() 6frcC ![]() 6fumC ![]() 6funC ![]() 6fuoC ![]() 6fupC ![]() 6fuqC ![]() 6furC S: Starting model for refinement C: citing same article ( |
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Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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Unit cell |
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Components
#1: Protein | Mass: 22510.129 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() ![]() | ||
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#2: Protein | Mass: 27534.910 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() ![]() | ||
#3: Chemical | ChemComp-EDO / ![]() | ||
#4: Chemical | ![]() #5: Water | ChemComp-HOH / | ![]() |
-Experimental details
-Experiment
Experiment | Method: ![]() |
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Sample preparation
Crystal | Density Matthews: 2.51 Å3/Da / Density % sol: 50.9 % |
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Crystal grow![]() | Temperature: 291 K / Method: vapor diffusion, sitting drop / pH: 6.5 / Details: 0.2M KSCN, 0.1M Bis-Tris, 20% PEG3350 |
-Data collection
Diffraction | Mean temperature: 100 K |
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Diffraction source | Source: ![]() ![]() ![]() |
Detector | Type: DECTRIS PILATUS3 S 6M / Detector: PIXEL / Date: Mar 8, 2012 |
Radiation | Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray |
Radiation wavelength | Wavelength![]() |
Reflection | Resolution: 2.31→72.53 Å / Num. obs: 21302 / % possible obs: 97.1 % / Redundancy: 3.7 % / Rmerge(I) obs: 0.077 / Rrim(I) all: 0.108 / Net I/σ(I): 9.2 |
Reflection shell | Resolution: 2.31→2.37 Å / Redundancy: 3.9 % / Rmerge(I) obs: 0.862 / Mean I/σ(I) obs: 2.5 / Num. unique obs: 1562 / Rrim(I) all: 1.077 / % possible all: 97.3 |
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Processing
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Refinement | Method to determine structure![]() ![]() Starting model: 6EH8 Resolution: 2.31→72.53 Å / Cor.coef. Fo:Fc: 0.943 / Cor.coef. Fo:Fc free: 0.912 / SU B: 22.135 / SU ML: 0.25 / Cross valid method: THROUGHOUT / ESU R: 0.414 / ESU R Free: 0.279 / Details: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS
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Solvent computation | Ion probe radii: 0.8 Å / Shrinkage radii: 0.8 Å / VDW probe radii: 1.2 Å | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Displacement parameters | Biso mean: 58.711 Å2
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Refinement step | Cycle: 1 / Resolution: 2.31→72.53 Å
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Refine LS restraints |
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