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Open data
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Basic information
Entry | Database: PDB / ID: 6fr3 | ||||||
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Title | 003 TCR Study of CDR Loop Flexibility | ||||||
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![]() | IMMUNE SYSTEM / 003 TCR / CDR Flexibility / 3D Structure / MHC Class I | ||||||
Function / homology | Immunoglobulins / Immunoglobulin-like / Sandwich / Mainly Beta / DI(HYDROXYETHYL)ETHER![]() | ||||||
Biological species | ![]() | ||||||
Method | ![]() ![]() ![]() | ||||||
![]() | Rizkallah, P.J. / Cole, D.K. | ||||||
![]() | ![]() Title: In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility. Authors: Holland, C.J. / MacLachlan, B.J. / Bianchi, V. / Hesketh, S.J. / Morgan, R. / Vickery, O. / Bulek, A.M. / Fuller, A. / Godkin, A. / Sewell, A.K. / Rizkallah, P.J. / Wells, S. / Cole, D.K. #1: ![]() Title: Flexibility Study of CDRs in 003 TCR Authors: Rizkallah, P.J. / Cole, D.K. | ||||||
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 211.9 KB | Display | ![]() |
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PDB format | ![]() | 168 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 486.2 KB | Display | ![]() |
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Full document | ![]() | 506.5 KB | Display | |
Data in XML | ![]() | 28.5 KB | Display | |
Data in CIF | ![]() | 41.3 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Related structure data | ![]() 6eh4SC ![]() 6eh5C ![]() 6eh6C ![]() 6eh7C ![]() 6eh8C ![]() 6eh9C ![]() 6fr4C ![]() 6fr5C ![]() 6fr6C ![]() 6fr7C ![]() 6fr8C ![]() 6fr9C ![]() 6fraC ![]() 6frbC ![]() 6frcC ![]() 6fumC ![]() 6funC ![]() 6fuoC ![]() 6fupC ![]() 6fuqC ![]() 6furC S: Starting model for refinement C: citing same article ( |
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Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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Unit cell |
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Components
#1: Protein | Mass: 22241.654 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() | ||||
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#2: Protein | Mass: 27451.434 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() | ||||
#3: Chemical | ChemComp-EDO / #4: Chemical | #5: Water | ChemComp-HOH / | |
-Experimental details
-Experiment
Experiment | Method: ![]() |
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Sample preparation
Crystal | Density Matthews: 2.28 Å3/Da / Density % sol: 46.16 % |
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Crystal grow | Temperature: 291 K / Method: vapor diffusion, sitting drop / pH: 7 Details: Pact Premier solution A04: 0.1 M SPG Buffer, pH 7.0, 25% PEG w/v 1500 |
-Data collection
Diffraction | Mean temperature: 100 K |
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Diffraction source | Source: ![]() ![]() ![]() |
Detector | Type: DECTRIS PILATUS3 6M / Detector: PIXEL / Date: Mar 17, 2013 |
Radiation | Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray |
Radiation wavelength | Wavelength: 0.92 Å / Relative weight: 1 |
Reflection | Resolution: 1.35→50.69 Å / Num. obs: 95658 / % possible obs: 97.8 % / Redundancy: 3.8 % / CC1/2: 0.998 / Rmerge(I) obs: 0.048 / Rrim(I) all: 0.056 / Net I/σ(I): 13.9 |
Reflection shell | Resolution: 1.35→1.385 Å / Redundancy: 3.5 % / Rmerge(I) obs: 0.496 / Num. unique obs: 6641 / CC1/2: 0.752 / Rrim(I) all: 0.587 / % possible all: 92.5 |
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Processing
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Refinement | Method to determine structure: ![]() Starting model: 6EH4 Resolution: 1.35→50.69 Å / Cor.coef. Fo:Fc: 0.972 / Cor.coef. Fo:Fc free: 0.961 / SU B: 1.915 / SU ML: 0.04 / Cross valid method: THROUGHOUT / ESU R: 0.055 / ESU R Free: 0.06 / Details: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS
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Solvent computation | Ion probe radii: 0.8 Å / Shrinkage radii: 0.8 Å / VDW probe radii: 1.2 Å | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Displacement parameters | Biso mean: 21.011 Å2
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Refinement step | Cycle: 1 / Resolution: 1.35→50.69 Å
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Refine LS restraints |
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