Entry | Database: PDB / ID: 6f3j |
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Title | The crystal structure of Glycogen Phosphorylase in complex with 10a |
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Components | Glycogen phosphorylase, muscle form |
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Keywords | TRANSFERASE |
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Function / homology | Function and homology information
glycogen phosphorylase / glycogen phosphorylase activity / linear malto-oligosaccharide phosphorylase activity / SHG alpha-glucan phosphorylase activity / glycogen catabolic process / skeletal muscle myofibril / pyridoxal phosphate binding / nucleotide bindingSimilarity search - Function Glycosyl transferase, family 35 / Glycogen/starch/alpha-glucan phosphorylase / Phosphorylase pyridoxal-phosphate attachment site / Carbohydrate phosphorylase / Phosphorylase pyridoxal-phosphate attachment site. / Glycogen Phosphorylase B; / Rossmann fold / 3-Layer(aba) Sandwich / Alpha BetaSimilarity search - Domain/homology |
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Biological species | ![](img/tx_mammal.gif) Oryctolagus cuniculus (rabbit) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / FOURIER SYNTHESIS / Resolution: 2.2 Å |
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Authors | Kyriakis, E. / Stamati, E.C.V. / Stravodimos, G.A. / Skamnaki, V.T. / Leonidas, D.D. |
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Citation | Journal: Eur J Med Chem / Year: 2018 Title: A multidisciplinary study of 3-( beta-d-glucopyranosyl)-5-substituted-1,2,4-triazole derivatives as glycogen phosphorylase inhibitors: Computation, synthesis, crystallography and kinetics ...Title: A multidisciplinary study of 3-( beta-d-glucopyranosyl)-5-substituted-1,2,4-triazole derivatives as glycogen phosphorylase inhibitors: Computation, synthesis, crystallography and kinetics reveal new potent inhibitors. Authors: Kun, S. / Begum, J. / Kyriakis, E. / Stamati, E.C.V. / Barkas, T.A. / Szennyes, E. / Bokor, E. / Szabo, K.E. / Stravodimos, G.A. / Sipos, A. / Docsa, T. / Gergely, P. / Moffatt, C. / ...Authors: Kun, S. / Begum, J. / Kyriakis, E. / Stamati, E.C.V. / Barkas, T.A. / Szennyes, E. / Bokor, E. / Szabo, K.E. / Stravodimos, G.A. / Sipos, A. / Docsa, T. / Gergely, P. / Moffatt, C. / Patraskaki, M.S. / Kokolaki, M.C. / Gkerdi, A. / Skamnaki, V.T. / Leonidas, D.D. / Somsak, L. / Hayes, J.M. |
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History | Deposition | Nov 28, 2017 | Deposition site: PDBE / Processing site: PDBE |
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Revision 1.0 | Feb 28, 2018 | Provider: repository / Type: Initial release |
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Revision 1.1 | May 1, 2024 | Group: Data collection / Database references / Refinement description Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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