Entry | Database: PDB / ID: 6ea6 |
---|
Title | Structure of VACV poxin 2'3' cGAMP-specific nuclease |
---|
Components | Protein B2 |
---|
Keywords | HYDROLASE / Vaccina virus / nuclease / cGAS / cGAMP / poxvirus / innate immunity |
---|
Function / homology | Nucleopolyhedrovirus p26 protein / Poxin, virus / nuclease activity / 2',3'-cyclic GMP-AMP binding / symbiont-mediated suppression of host innate immune response / host cell cytoplasm / Hydrolases; Acting on ester bonds / Poxin Function and homology information |
---|
Biological species | Vaccinia virus WR |
---|
Method | X-RAY DIFFRACTION / SYNCHROTRON / SAD / Resolution: 1.703 Å |
---|
Authors | Eaglesham, J.B. / Kranzusch, P.J. |
---|
Citation | Journal: Nature / Year: 2019 Title: Viral and metazoan poxins are cGAMP-specific nucleases that restrict cGAS-STING signalling. Authors: Eaglesham, J.B. / Pan, Y. / Kupper, T.S. / Kranzusch, P.J. |
---|
History | Deposition | Aug 2, 2018 | Deposition site: RCSB / Processing site: RCSB |
---|
Revision 1.0 | Feb 6, 2019 | Provider: repository / Type: Initial release |
---|
Revision 1.1 | Feb 20, 2019 | Group: Data collection / Database references / Category: citation / Item: _citation.pdbx_database_id_PubMed / _citation.title |
---|
Revision 1.2 | Feb 27, 2019 | Group: Data collection / Database references / Category: citation Item: _citation.journal_volume / _citation.page_first / _citation.page_last |
---|
Revision 1.3 | Dec 11, 2019 | Group: Derived calculations Category: pdbx_struct_assembly_gen / pdbx_struct_assembly_prop / pdbx_struct_oper_list Item: _pdbx_struct_assembly_prop.value |
---|
|
---|