PDB-6e3b: STRUCTURE OF Siw14 CATALYTIC CORE

Basic information

• Entry: Database: PDB / ID: 6e3b
• Title: STRUCTURE OF Siw14 CATALYTIC CORE
• Components: Tyrosine-protein phosphatase SIW14
• Keywords: HYDROLASE / dual specificity phosphatase / inositol phosphate / VH1-like phosphatase

Function / homology

Function:

inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity / inositol-5-diphosphate-1,3,4,6-tetrakisphosphate diphosphatase activity / inositol diphosphate tetrakisphosphate diphosphatase activity / inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity / diphosphoinositol polyphosphate metabolic process / inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity / diphosphoinositol-polyphosphate diphosphatase / phosphatase activity / actin filament organization / cytosol / cytoplasm

Domain/homology:

Atypical dual-specificity phosphatase Siw14-like, plant and fungi / Atypical dual-specificity phosphatase Siw14-like / Tyrosine phosphatase family / Dual specificity protein phosphatase domain profile. / Dual specificity protein phosphatase domain / Protein tyrosine phosphatase superfamily / Protein-Tyrosine Phosphatase; Chain A / Tyrosine specific protein phosphatases active site. / Protein-tyrosine phosphatase, active site / Protein-tyrosine phosphatase-like / Alpha-Beta Complex / Alpha Beta

Component:

Inositol diphosphatase SIW14

• Biological species: Saccharomyces cerevisiae (brewer's yeast)
• Method: X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.5 Å
• Authors: Florio, T. / Lokareddy, R. / Cingolani, G.

Funding support

United States, 3items

Organization	Grant number	Country
National Institutes of Health/National Cancer Institute (NIH/NCI)	P30CA56036	United States
National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)	R01GM122844	United States
National Institutes of Health/Office of the Director	S10OD017987	United States

• Citation: Journal: Biochemistry / Year: 2019; Title: Molecular Architecture of the Inositol Phosphatase Siw14.; Authors: Florio, T.J. / Lokareddy, R.K. / Gillilan, R.E. / Cingolani, G.

History

Deposition	Jul 13, 2018	Deposition site: RCSB / Processing site: RCSB
Revision 1.0	Feb 27, 2019	Provider: repository / Type: Initial release
Revision 1.1	Dec 4, 2019	Group: Author supporting evidence / Category: pdbx_audit_support / Item: _pdbx_audit_support.funding_organization
Revision 1.2	Oct 11, 2023	Group: Data collection / Database references / Refinement description Category: chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_ncs_dom_lim Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id / _struct_ncs_dom_lim.beg_label_comp_id / _struct_ncs_dom_lim.beg_label_seq_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ncs_dom_lim.end_label_asym_id / _struct_ncs_dom_lim.end_label_comp_id / _struct_ncs_dom_lim.end_label_seq_id

Assembly

Deposited unit

A: Tyrosine-protein phosphatase SIW14

B: Tyrosine-protein phosphatase SIW14

C: Tyrosine-protein phosphatase SIW14

D: Tyrosine-protein phosphatase SIW14

E: Tyrosine-protein phosphatase SIW14

F: Tyrosine-protein phosphatase SIW14

G: Tyrosine-protein phosphatase SIW14

H: Tyrosine-protein phosphatase SIW14

I: Tyrosine-protein phosphatase SIW14

J: Tyrosine-protein phosphatase SIW14

K: Tyrosine-protein phosphatase SIW14

L: Tyrosine-protein phosphatase SIW14

M: Tyrosine-protein phosphatase SIW14

N: Tyrosine-protein phosphatase SIW14

O: Tyrosine-protein phosphatase SIW14

P: Tyrosine-protein phosphatase SIW14

Q: Tyrosine-protein phosphatase SIW14

R: Tyrosine-protein phosphatase SIW14

S: Tyrosine-protein phosphatase SIW14

T: Tyrosine-protein phosphatase SIW14

V: Tyrosine-protein phosphatase SIW14

W: Tyrosine-protein phosphatase SIW14

X: Tyrosine-protein phosphatase SIW14

Y: Tyrosine-protein phosphatase SIW14

hetero molecules

Summary:

• 479 kDa, 24 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	479,017	48
Polymers	476,712	24
Non-polymers	2,306	24
Water	6,936	385

1

A: Tyrosine-protein phosphatase SIW14

hetero molecules

Summary:

• defined by author
• Evidence: equilibrium centrifugation, gel filtration
• 20 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	19,959	2
Polymers	19,863	1
Non-polymers	96	1
Water	18	1

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

2

B: Tyrosine-protein phosphatase SIW14

hetero molecules

Summary:

• defined by author
• 20 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	19,959	2
Polymers	19,863	1
Non-polymers	96	1
Water	18	1

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

3

C: Tyrosine-protein phosphatase SIW14

hetero molecules

Summary:

• defined by author
• 20 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	19,959	2
Polymers	19,863	1
Non-polymers	96	1
Water	18	1

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

4

D: Tyrosine-protein phosphatase SIW14

hetero molecules

Summary:

• defined by author
• 20 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	19,959	2
Polymers	19,863	1
Non-polymers	96	1
Water	18	1

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

5

E: Tyrosine-protein phosphatase SIW14

hetero molecules

Summary:

• defined by author
• 20 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	19,959	2
Polymers	19,863	1
Non-polymers	96	1
Water	18	1

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

6

F: Tyrosine-protein phosphatase SIW14

hetero molecules

Summary:

• defined by author
• 20 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	19,959	2
Polymers	19,863	1
Non-polymers	96	1
Water	18	1

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

7

G: Tyrosine-protein phosphatase SIW14

hetero molecules

Summary:

• defined by author
• 20 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	19,959	2
Polymers	19,863	1
Non-polymers	96	1
Water	18	1

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

8

H: Tyrosine-protein phosphatase SIW14

hetero molecules

Summary:

• defined by author
• 20 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	19,959	2
Polymers	19,863	1
Non-polymers	96	1
Water	18	1

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

9

I: Tyrosine-protein phosphatase SIW14

hetero molecules

Summary:

• defined by author
• 20 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	19,959	2
Polymers	19,863	1
Non-polymers	96	1
Water	18	1

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

10

J: Tyrosine-protein phosphatase SIW14

hetero molecules

Summary:

• defined by author
• 20 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	19,959	2
Polymers	19,863	1
Non-polymers	96	1
Water	18	1

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

11

K: Tyrosine-protein phosphatase SIW14

hetero molecules

Summary:

• defined by author
• 20 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	19,959	2
Polymers	19,863	1
Non-polymers	96	1
Water	18	1

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

12

L: Tyrosine-protein phosphatase SIW14

hetero molecules

Summary:

• defined by author
• 20 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	19,959	2
Polymers	19,863	1
Non-polymers	96	1
Water	18	1

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

13

M: Tyrosine-protein phosphatase SIW14

hetero molecules

Summary:

• defined by author
• 20 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	19,959	2
Polymers	19,863	1
Non-polymers	96	1
Water	18	1

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

14

N: Tyrosine-protein phosphatase SIW14

hetero molecules

Summary:

• defined by author
• 20 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	19,959	2
Polymers	19,863	1
Non-polymers	96	1
Water	18	1

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

15

O: Tyrosine-protein phosphatase SIW14

hetero molecules

Summary:

• defined by author
• 20 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	19,959	2
Polymers	19,863	1
Non-polymers	96	1
Water	18	1

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

16

P: Tyrosine-protein phosphatase SIW14

hetero molecules

Summary:

• defined by author
• 20 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	19,959	2
Polymers	19,863	1
Non-polymers	96	1
Water	18	1

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

17

Q: Tyrosine-protein phosphatase SIW14

hetero molecules

Summary:

• defined by author
• 20 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	19,959	2
Polymers	19,863	1
Non-polymers	96	1
Water	18	1

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

18

R: Tyrosine-protein phosphatase SIW14

hetero molecules

Summary:

• defined by author
• 20 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	19,959	2
Polymers	19,863	1
Non-polymers	96	1
Water	18	1

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

19

S: Tyrosine-protein phosphatase SIW14

hetero molecules

Summary:

• defined by author
• 20 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	19,959	2
Polymers	19,863	1
Non-polymers	96	1
Water	18	1

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

20

T: Tyrosine-protein phosphatase SIW14

hetero molecules

Summary:

• defined by author
• 20 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	19,959	2
Polymers	19,863	1
Non-polymers	96	1
Water	18	1

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

21

V: Tyrosine-protein phosphatase SIW14

hetero molecules

Summary:

• defined by author
• 20 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	19,959	2
Polymers	19,863	1
Non-polymers	96	1
Water	18	1

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

22

W: Tyrosine-protein phosphatase SIW14

hetero molecules

Summary:

• defined by author
• 20 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	19,959	2
Polymers	19,863	1
Non-polymers	96	1
Water	18	1

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

23

X: Tyrosine-protein phosphatase SIW14

hetero molecules

Summary:

• defined by author
• 20 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	19,959	2
Polymers	19,863	1
Non-polymers	96	1
Water	18	1

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

24

Y: Tyrosine-protein phosphatase SIW14

hetero molecules

Summary:

• defined by author
• 20 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	19,959	2
Polymers	19,863	1
Non-polymers	96	1
Water	18	1

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Unit cell

Length a, b, c (Å)	92.467, 160.487, 360.572
Angle α, β, γ (deg.)	90.000, 90.320, 90.000
Int Tables number	5
Space group name H-M	C121

Noncrystallographic symmetry (NCS)

NCS domain:

ID	Ens-ID	Details
1	1	(chain A and (resid 113 through 116 or (resid 117...
2	1	(chain B and (resid 113 through 116 or (resid 117...
3	1	(chain C and (resid 113 through 116 or (resid 117...
4	1	(chain D and (resid 113 through 116 or (resid 117...
5	1	(chain E and (resid 113 through 116 or (resid 117...
6	1	(chain F and (resid 113 through 116 or (resid 117...
7	1	(chain G and (resid 113 through 116 or (resid 117...
8	1	(chain H and (resid 113 through 116 or (resid 117...
9	1	(chain I and (resid 113 through 116 or (resid 117...
10	1	(chain J and (resid 113 through 116 or (resid 117...
11	1	(chain K and (resid 113 through 116 or (resid 117...
12	1	(chain L and (resid 113 through 116 or (resid 117...
13	1	(chain M and (resid 113 through 116 or (resid 117...
14	1	(chain N and (resid 113 through 116 or (resid 117...
15	1	(chain O and (resid 113 through 116 or (resid 117...
16	1	(chain P and (resid 113 through 116 or (resid 117...
17	1	(chain Q and (resid 113 through 116 or (resid 117...
18	1	(chain R and (resid 113 through 116 or (resid 117...
19	1	(chain S and (resid 113 through 154 or resid 156...
20	1	(chain T and (resid 113 through 116 or (resid 117...
21	1	(chain V and (resid 113 through 116 or (resid 117...
22	1	(chain W and (resid 113 through 116 or (resid 117...
23	1	(chain X and (resid 113 through 116 or (resid 117...
24	1	(chain Y and (resid 113 through 116 or (resid 117...

NCS domain segments:

Ens-ID: 1

Dom-ID	Component-ID	Beg auth comp-ID	Beg label comp-ID	End auth comp-ID	End label comp-ID	Selection details	Auth asym-ID	Label asym-ID	Auth seq-ID	Label seq-ID
1	1	ASN	ASN	VAL	VAL	(chain A and (resid 113 through 116 or (resid 117...	A	A	113 - 116	1 - 4
1	2	ILE	ILE	ILE	ILE	(chain A and (resid 113 through 116 or (resid 117...	A	A	117	5
1	3	ASN	ASN	TRP	TRP	(chain A and (resid 113 through 116 or (resid 117...	A	A	113 - 281	1 - 169
1	4	ASN	ASN	TRP	TRP	(chain A and (resid 113 through 116 or (resid 117...	A	A	113 - 281	1 - 169
1	5	ASN	ASN	TRP	TRP	(chain A and (resid 113 through 116 or (resid 117...	A	A	113 - 281	1 - 169
1	6	ASN	ASN	TRP	TRP	(chain A and (resid 113 through 116 or (resid 117...	A	A	113 - 281	1 - 169
1	7	ASN	ASN	TRP	TRP	(chain A and (resid 113 through 116 or (resid 117...	A	A	113 - 281	1 - 169
1	8	ASN	ASN	TRP	TRP	(chain A and (resid 113 through 116 or (resid 117...	A	A	113 - 281	1 - 169
2	1	ASN	ASN	VAL	VAL	(chain B and (resid 113 through 116 or (resid 117...	B	B	113 - 116	1 - 4
2	2	ILE	ILE	ILE	ILE	(chain B and (resid 113 through 116 or (resid 117...	B	B	117	5
2	3	ASN	ASN	TRP	TRP	(chain B and (resid 113 through 116 or (resid 117...	B	B	113 - 281	1 - 169
2	4	ASN	ASN	TRP	TRP	(chain B and (resid 113 through 116 or (resid 117...	B	B	113 - 281	1 - 169
2	5	ASN	ASN	TRP	TRP	(chain B and (resid 113 through 116 or (resid 117...	B	B	113 - 281	1 - 169
2	6	ASN	ASN	TRP	TRP	(chain B and (resid 113 through 116 or (resid 117...	B	B	113 - 281	1 - 169
2	7	ASN	ASN	TRP	TRP	(chain B and (resid 113 through 116 or (resid 117...	B	B	113 - 281	1 - 169
3	1	ASN	ASN	VAL	VAL	(chain C and (resid 113 through 116 or (resid 117...	C	C	113 - 116	1 - 4
3	2	ILE	ILE	ILE	ILE	(chain C and (resid 113 through 116 or (resid 117...	C	C	117	5
3	3	ASN	ASN	TRP	TRP	(chain C and (resid 113 through 116 or (resid 117...	C	C	113 - 281	1 - 169
3	4	ASN	ASN	TRP	TRP	(chain C and (resid 113 through 116 or (resid 117...	C	C	113 - 281	1 - 169
3	5	ASN	ASN	TRP	TRP	(chain C and (resid 113 through 116 or (resid 117...	C	C	113 - 281	1 - 169
3	6	ASN	ASN	TRP	TRP	(chain C and (resid 113 through 116 or (resid 117...	C	C	113 - 281	1 - 169
3	7	ASN	ASN	TRP	TRP	(chain C and (resid 113 through 116 or (resid 117...	C	C	113 - 281	1 - 169
3	8	ASN	ASN	TRP	TRP	(chain C and (resid 113 through 116 or (resid 117...	C	C	113 - 281	1 - 169
4	1	ASN	ASN	VAL	VAL	(chain D and (resid 113 through 116 or (resid 117...	D	D	113 - 116	1 - 4
4	2	ILE	ILE	ILE	ILE	(chain D and (resid 113 through 116 or (resid 117...	D	D	117	5
4	3	ASN	ASN	TRP	TRP	(chain D and (resid 113 through 116 or (resid 117...	D	D	113 - 281	1 - 169
4	4	ASN	ASN	TRP	TRP	(chain D and (resid 113 through 116 or (resid 117...	D	D	113 - 281	1 - 169
4	5	ASN	ASN	TRP	TRP	(chain D and (resid 113 through 116 or (resid 117...	D	D	113 - 281	1 - 169
4	6	ASN	ASN	TRP	TRP	(chain D and (resid 113 through 116 or (resid 117...	D	D	113 - 281	1 - 169
4	7	ASN	ASN	TRP	TRP	(chain D and (resid 113 through 116 or (resid 117...	D	D	113 - 281	1 - 169
4	8	ASN	ASN	TRP	TRP	(chain D and (resid 113 through 116 or (resid 117...	D	D	113 - 281	1 - 169
5	1	ASN	ASN	VAL	VAL	(chain E and (resid 113 through 116 or (resid 117...	E	E	113 - 116	1 - 4
5	2	ILE	ILE	ILE	ILE	(chain E and (resid 113 through 116 or (resid 117...	E	E	117	5
5	3	ASN	ASN	TRP	TRP	(chain E and (resid 113 through 116 or (resid 117...	E	E	113 - 281	1 - 169
5	4	ASN	ASN	TRP	TRP	(chain E and (resid 113 through 116 or (resid 117...	E	E	113 - 281	1 - 169
5	5	ASN	ASN	TRP	TRP	(chain E and (resid 113 through 116 or (resid 117...	E	E	113 - 281	1 - 169
5	6	ASN	ASN	TRP	TRP	(chain E and (resid 113 through 116 or (resid 117...	E	E	113 - 281	1 - 169
5	7	ASN	ASN	TRP	TRP	(chain E and (resid 113 through 116 or (resid 117...	E	E	113 - 281	1 - 169
5	8	ASN	ASN	TRP	TRP	(chain E and (resid 113 through 116 or (resid 117...	E	E	113 - 281	1 - 169
6	1	ASN	ASN	VAL	VAL	(chain F and (resid 113 through 116 or (resid 117...	F	F	113 - 116	1 - 4
6	2	ILE	ILE	ILE	ILE	(chain F and (resid 113 through 116 or (resid 117...	F	F	117	5
6	3	ASN	ASN	TRP	TRP	(chain F and (resid 113 through 116 or (resid 117...	F	F	113 - 281	1 - 169
6	4	ASN	ASN	TRP	TRP	(chain F and (resid 113 through 116 or (resid 117...	F	F	113 - 281	1 - 169
6	5	ASN	ASN	TRP	TRP	(chain F and (resid 113 through 116 or (resid 117...	F	F	113 - 281	1 - 169
6	6	ASN	ASN	TRP	TRP	(chain F and (resid 113 through 116 or (resid 117...	F	F	113 - 281	1 - 169
6	7	ASN	ASN	TRP	TRP	(chain F and (resid 113 through 116 or (resid 117...	F	F	113 - 281	1 - 169
7	1	ASN	ASN	VAL	VAL	(chain G and (resid 113 through 116 or (resid 117...	G	G	113 - 116	1 - 4
7	2	ILE	ILE	ILE	ILE	(chain G and (resid 113 through 116 or (resid 117...	G	G	117	5
7	3	ASN	ASN	TRP	TRP	(chain G and (resid 113 through 116 or (resid 117...	G	G	113 - 281	1 - 169
7	4	ASN	ASN	TRP	TRP	(chain G and (resid 113 through 116 or (resid 117...	G	G	113 - 281	1 - 169
7	5	ASN	ASN	TRP	TRP	(chain G and (resid 113 through 116 or (resid 117...	G	G	113 - 281	1 - 169
7	6	ASN	ASN	TRP	TRP	(chain G and (resid 113 through 116 or (resid 117...	G	G	113 - 281	1 - 169
7	7	ASN	ASN	TRP	TRP	(chain G and (resid 113 through 116 or (resid 117...	G	G	113 - 281	1 - 169
7	8	ASN	ASN	TRP	TRP	(chain G and (resid 113 through 116 or (resid 117...	G	G	113 - 281	1 - 169
8	1	ASN	ASN	VAL	VAL	(chain H and (resid 113 through 116 or (resid 117...	H	H	113 - 116	1 - 4
8	2	ILE	ILE	ILE	ILE	(chain H and (resid 113 through 116 or (resid 117...	H	H	117	5
8	3	ASN	ASN	TRP	TRP	(chain H and (resid 113 through 116 or (resid 117...	H	H	113 - 281	1 - 169
8	4	ASN	ASN	TRP	TRP	(chain H and (resid 113 through 116 or (resid 117...	H	H	113 - 281	1 - 169
8	5	ASN	ASN	TRP	TRP	(chain H and (resid 113 through 116 or (resid 117...	H	H	113 - 281	1 - 169
8	6	ASN	ASN	TRP	TRP	(chain H and (resid 113 through 116 or (resid 117...	H	H	113 - 281	1 - 169
8	7	ASN	ASN	TRP	TRP	(chain H and (resid 113 through 116 or (resid 117...	H	H	113 - 281	1 - 169
8	8	ASN	ASN	TRP	TRP	(chain H and (resid 113 through 116 or (resid 117...	H	H	113 - 281	1 - 169
9	1	ASN	ASN	VAL	VAL	(chain I and (resid 113 through 116 or (resid 117...	I	I	113 - 116	1 - 4
9	2	ILE	ILE	ILE	ILE	(chain I and (resid 113 through 116 or (resid 117...	I	I	117	5
9	3	ASN	ASN	TRP	TRP	(chain I and (resid 113 through 116 or (resid 117...	I	I	113 - 281	1 - 169
9	4	ASN	ASN	TRP	TRP	(chain I and (resid 113 through 116 or (resid 117...	I	I	113 - 281	1 - 169
9	5	ASN	ASN	TRP	TRP	(chain I and (resid 113 through 116 or (resid 117...	I	I	113 - 281	1 - 169
9	6	ASN	ASN	TRP	TRP	(chain I and (resid 113 through 116 or (resid 117...	I	I	113 - 281	1 - 169
9	7	ASN	ASN	TRP	TRP	(chain I and (resid 113 through 116 or (resid 117...	I	I	113 - 281	1 - 169
9	8	ASN	ASN	TRP	TRP	(chain I and (resid 113 through 116 or (resid 117...	I	I	113 - 281	1 - 169
10	1	ASN	ASN	VAL	VAL	(chain J and (resid 113 through 116 or (resid 117...	J	J	113 - 116	1 - 4
10	2	ILE	ILE	ILE	ILE	(chain J and (resid 113 through 116 or (resid 117...	J	J	117	5
10	3	ASN	ASN	TRP	TRP	(chain J and (resid 113 through 116 or (resid 117...	J	J	113 - 281	1 - 169
10	4	ASN	ASN	TRP	TRP	(chain J and (resid 113 through 116 or (resid 117...	J	J	113 - 281	1 - 169
10	5	ASN	ASN	TRP	TRP	(chain J and (resid 113 through 116 or (resid 117...	J	J	113 - 281	1 - 169
10	6	ASN	ASN	TRP	TRP	(chain J and (resid 113 through 116 or (resid 117...	J	J	113 - 281	1 - 169
10	7	ASN	ASN	TRP	TRP	(chain J and (resid 113 through 116 or (resid 117...	J	J	113 - 281	1 - 169
11	1	ASN	ASN	VAL	VAL	(chain K and (resid 113 through 116 or (resid 117...	K	K	113 - 116	1 - 4
11	2	ILE	ILE	ILE	ILE	(chain K and (resid 113 through 116 or (resid 117...	K	K	117	5
11	3	ASN	ASN	TRP	TRP	(chain K and (resid 113 through 116 or (resid 117...	K	K	113 - 281	1 - 169
11	4	ASN	ASN	TRP	TRP	(chain K and (resid 113 through 116 or (resid 117...	K	K	113 - 281	1 - 169
11	5	ASN	ASN	TRP	TRP	(chain K and (resid 113 through 116 or (resid 117...	K	K	113 - 281	1 - 169
11	6	ASN	ASN	TRP	TRP	(chain K and (resid 113 through 116 or (resid 117...	K	K	113 - 281	1 - 169
11	7	ASN	ASN	TRP	TRP	(chain K and (resid 113 through 116 or (resid 117...	K	K	113 - 281	1 - 169
11	8	ASN	ASN	TRP	TRP	(chain K and (resid 113 through 116 or (resid 117...	K	K	113 - 281	1 - 169
12	1	ASN	ASN	VAL	VAL	(chain L and (resid 113 through 116 or (resid 117...	L	L	113 - 116	1 - 4
12	2	ILE	ILE	ILE	ILE	(chain L and (resid 113 through 116 or (resid 117...	L	L	117	5
12	3	ASN	ASN	TRP	TRP	(chain L and (resid 113 through 116 or (resid 117...	L	L	113 - 281	1 - 169
12	4	ASN	ASN	TRP	TRP	(chain L and (resid 113 through 116 or (resid 117...	L	L	113 - 281	1 - 169
12	5	ASN	ASN	TRP	TRP	(chain L and (resid 113 through 116 or (resid 117...	L	L	113 - 281	1 - 169
12	6	ASN	ASN	TRP	TRP	(chain L and (resid 113 through 116 or (resid 117...	L	L	113 - 281	1 - 169
12	7	ASN	ASN	TRP	TRP	(chain L and (resid 113 through 116 or (resid 117...	L	L	113 - 281	1 - 169
12	8	ASN	ASN	TRP	TRP	(chain L and (resid 113 through 116 or (resid 117...	L	L	113 - 281	1 - 169
13	1	ASN	ASN	VAL	VAL	(chain M and (resid 113 through 116 or (resid 117...	M	M	113 - 116	1 - 4
13	2	ILE	ILE	ILE	ILE	(chain M and (resid 113 through 116 or (resid 117...	M	M	117	5
13	3	ASN	ASN	TRP	TRP	(chain M and (resid 113 through 116 or (resid 117...	M	M	113 - 281	1 - 169
13	4	ASN	ASN	TRP	TRP	(chain M and (resid 113 through 116 or (resid 117...	M	M	113 - 281	1 - 169
13	5	ASN	ASN	TRP	TRP	(chain M and (resid 113 through 116 or (resid 117...	M	M	113 - 281	1 - 169
13	6	ASN	ASN	TRP	TRP	(chain M and (resid 113 through 116 or (resid 117...	M	M	113 - 281	1 - 169
13	7	ASN	ASN	TRP	TRP	(chain M and (resid 113 through 116 or (resid 117...	M	M	113 - 281	1 - 169
13	8	ASN	ASN	TRP	TRP	(chain M and (resid 113 through 116 or (resid 117...	M	M	113 - 281	1 - 169
14	1	ASN	ASN	VAL	VAL	(chain N and (resid 113 through 116 or (resid 117...	N	N	113 - 116	1 - 4
14	2	ILE	ILE	ILE	ILE	(chain N and (resid 113 through 116 or (resid 117...	N	N	117	5
14	3	ASN	ASN	TRP	TRP	(chain N and (resid 113 through 116 or (resid 117...	N	N	113 - 281	1 - 169
14	4	ASN	ASN	TRP	TRP	(chain N and (resid 113 through 116 or (resid 117...	N	N	113 - 281	1 - 169
14	5	ASN	ASN	TRP	TRP	(chain N and (resid 113 through 116 or (resid 117...	N	N	113 - 281	1 - 169
14	6	ASN	ASN	TRP	TRP	(chain N and (resid 113 through 116 or (resid 117...	N	N	113 - 281	1 - 169
14	7	ASN	ASN	TRP	TRP	(chain N and (resid 113 through 116 or (resid 117...	N	N	113 - 281	1 - 169
15	1	ASN	ASN	VAL	VAL	(chain O and (resid 113 through 116 or (resid 117...	O	O	113 - 116	1 - 4
15	2	ILE	ILE	ILE	ILE	(chain O and (resid 113 through 116 or (resid 117...	O	O	117	5
15	3	ASN	ASN	TRP	TRP	(chain O and (resid 113 through 116 or (resid 117...	O	O	113 - 281	1 - 169
15	4	ASN	ASN	TRP	TRP	(chain O and (resid 113 through 116 or (resid 117...	O	O	113 - 281	1 - 169
15	5	ASN	ASN	TRP	TRP	(chain O and (resid 113 through 116 or (resid 117...	O	O	113 - 281	1 - 169
15	6	ASN	ASN	TRP	TRP	(chain O and (resid 113 through 116 or (resid 117...	O	O	113 - 281	1 - 169
15	7	ASN	ASN	TRP	TRP	(chain O and (resid 113 through 116 or (resid 117...	O	O	113 - 281	1 - 169
15	8	ASN	ASN	TRP	TRP	(chain O and (resid 113 through 116 or (resid 117...	O	O	113 - 281	1 - 169
16	1	ASN	ASN	VAL	VAL	(chain P and (resid 113 through 116 or (resid 117...	P	P	113 - 116	1 - 4
16	2	ILE	ILE	ILE	ILE	(chain P and (resid 113 through 116 or (resid 117...	P	P	117	5
16	3	ASN	ASN	TRP	TRP	(chain P and (resid 113 through 116 or (resid 117...	P	P	113 - 281	1 - 169
16	4	ASN	ASN	TRP	TRP	(chain P and (resid 113 through 116 or (resid 117...	P	P	113 - 281	1 - 169
16	5	ASN	ASN	TRP	TRP	(chain P and (resid 113 through 116 or (resid 117...	P	P	113 - 281	1 - 169
16	6	ASN	ASN	TRP	TRP	(chain P and (resid 113 through 116 or (resid 117...	P	P	113 - 281	1 - 169
16	7	ASN	ASN	TRP	TRP	(chain P and (resid 113 through 116 or (resid 117...	P	P	113 - 281	1 - 169
16	8	ASN	ASN	TRP	TRP	(chain P and (resid 113 through 116 or (resid 117...	P	P	113 - 281	1 - 169
17	1	ASN	ASN	VAL	VAL	(chain Q and (resid 113 through 116 or (resid 117...	Q	Q	113 - 116	1 - 4
17	2	ILE	ILE	ILE	ILE	(chain Q and (resid 113 through 116 or (resid 117...	Q	Q	117	5
17	3	ASN	ASN	TRP	TRP	(chain Q and (resid 113 through 116 or (resid 117...	Q	Q	113 - 281	1 - 169
17	4	ASN	ASN	TRP	TRP	(chain Q and (resid 113 through 116 or (resid 117...	Q	Q	113 - 281	1 - 169
17	5	ASN	ASN	TRP	TRP	(chain Q and (resid 113 through 116 or (resid 117...	Q	Q	113 - 281	1 - 169
17	6	ASN	ASN	TRP	TRP	(chain Q and (resid 113 through 116 or (resid 117...	Q	Q	113 - 281	1 - 169
17	7	ASN	ASN	TRP	TRP	(chain Q and (resid 113 through 116 or (resid 117...	Q	Q	113 - 281	1 - 169
17	8	ASN	ASN	TRP	TRP	(chain Q and (resid 113 through 116 or (resid 117...	Q	Q	113 - 281	1 - 169
18	1	ASN	ASN	VAL	VAL	(chain R and (resid 113 through 116 or (resid 117...	R	R	113 - 116	1 - 4
18	2	ILE	ILE	ILE	ILE	(chain R and (resid 113 through 116 or (resid 117...	R	R	117	5
18	3	ASN	ASN	TRP	TRP	(chain R and (resid 113 through 116 or (resid 117...	R	R	113 - 281	1 - 169
18	4	ASN	ASN	TRP	TRP	(chain R and (resid 113 through 116 or (resid 117...	R	R	113 - 281	1 - 169
18	5	ASN	ASN	TRP	TRP	(chain R and (resid 113 through 116 or (resid 117...	R	R	113 - 281	1 - 169
18	6	ASN	ASN	TRP	TRP	(chain R and (resid 113 through 116 or (resid 117...	R	R	113 - 281	1 - 169
18	7	ASN	ASN	TRP	TRP	(chain R and (resid 113 through 116 or (resid 117...	R	R	113 - 281	1 - 169
19	1	ASN	ASN	VAL	VAL	(chain S and (resid 113 through 154 or resid 156...	S	S	113 - 154	1 - 42
19	2	ILE	ILE	ASN	ASN	(chain S and (resid 113 through 154 or resid 156...	S	S	156 - 183	44 - 71
19	3	PRO	PRO	ASN	ASN	(chain S and (resid 113 through 154 or resid 156...	S	S	186 - 215	74 - 103
19	4	GLY	GLY	TRP	TRP	(chain S and (resid 113 through 154 or resid 156...	S	S	217 - 281	105 - 169
20	1	ASN	ASN	VAL	VAL	(chain T and (resid 113 through 116 or (resid 117...	T	T	113 - 116	1 - 4
20	2	ILE	ILE	ILE	ILE	(chain T and (resid 113 through 116 or (resid 117...	T	T	117	5
20	3	ASN	ASN	TRP	TRP	(chain T and (resid 113 through 116 or (resid 117...	T	T	113 - 281	1 - 169
20	4	ASN	ASN	TRP	TRP	(chain T and (resid 113 through 116 or (resid 117...	T	T	113 - 281	1 - 169
20	5	ASN	ASN	TRP	TRP	(chain T and (resid 113 through 116 or (resid 117...	T	T	113 - 281	1 - 169
20	6	ASN	ASN	TRP	TRP	(chain T and (resid 113 through 116 or (resid 117...	T	T	113 - 281	1 - 169
20	7	ASN	ASN	TRP	TRP	(chain T and (resid 113 through 116 or (resid 117...	T	T	113 - 281	1 - 169
21	1	ASN	ASN	VAL	VAL	(chain V and (resid 113 through 116 or (resid 117...	V	U	113 - 116	1 - 4
21	2	ILE	ILE	ILE	ILE	(chain V and (resid 113 through 116 or (resid 117...	V	U	117	5
21	3	ASN	ASN	TRP	TRP	(chain V and (resid 113 through 116 or (resid 117...	V	U	113 - 281	1 - 169
21	4	ASN	ASN	TRP	TRP	(chain V and (resid 113 through 116 or (resid 117...	V	U	113 - 281	1 - 169
21	5	ASN	ASN	TRP	TRP	(chain V and (resid 113 through 116 or (resid 117...	V	U	113 - 281	1 - 169
21	6	ASN	ASN	TRP	TRP	(chain V and (resid 113 through 116 or (resid 117...	V	U	113 - 281	1 - 169
21	7	ASN	ASN	TRP	TRP	(chain V and (resid 113 through 116 or (resid 117...	V	U	113 - 281	1 - 169
22	1	ASN	ASN	VAL	VAL	(chain W and (resid 113 through 116 or (resid 117...	W	V	113 - 116	1 - 4
22	2	ILE	ILE	ILE	ILE	(chain W and (resid 113 through 116 or (resid 117...	W	V	117	5
22	3	ASN	ASN	TRP	TRP	(chain W and (resid 113 through 116 or (resid 117...	W	V	113 - 281	1 - 169
22	4	ASN	ASN	TRP	TRP	(chain W and (resid 113 through 116 or (resid 117...	W	V	113 - 281	1 - 169
22	5	ASN	ASN	TRP	TRP	(chain W and (resid 113 through 116 or (resid 117...	W	V	113 - 281	1 - 169
22	6	ASN	ASN	TRP	TRP	(chain W and (resid 113 through 116 or (resid 117...	W	V	113 - 281	1 - 169
22	7	ASN	ASN	TRP	TRP	(chain W and (resid 113 through 116 or (resid 117...	W	V	113 - 281	1 - 169
23	1	ASN	ASN	VAL	VAL	(chain X and (resid 113 through 116 or (resid 117...	X	W	113 - 116	1 - 4
23	2	ILE	ILE	ILE	ILE	(chain X and (resid 113 through 116 or (resid 117...	X	W	117	5
23	3	ASN	ASN	TRP	TRP	(chain X and (resid 113 through 116 or (resid 117...	X	W	113 - 281	1 - 169
23	4	ASN	ASN	TRP	TRP	(chain X and (resid 113 through 116 or (resid 117...	X	W	113 - 281	1 - 169
23	5	ASN	ASN	TRP	TRP	(chain X and (resid 113 through 116 or (resid 117...	X	W	113 - 281	1 - 169
23	6	ASN	ASN	TRP	TRP	(chain X and (resid 113 through 116 or (resid 117...	X	W	113 - 281	1 - 169
23	7	ASN	ASN	TRP	TRP	(chain X and (resid 113 through 116 or (resid 117...	X	W	113 - 281	1 - 169
24	1	ASN	ASN	VAL	VAL	(chain Y and (resid 113 through 116 or (resid 117...	Y	X	113 - 116	1 - 4
24	2	ILE	ILE	ILE	ILE	(chain Y and (resid 113 through 116 or (resid 117...	Y	X	117	5
24	3	ASN	ASN	TRP	TRP	(chain Y and (resid 113 through 116 or (resid 117...	Y	X	113 - 281	1 - 169
24	4	ASN	ASN	TRP	TRP	(chain Y and (resid 113 through 116 or (resid 117...	Y	X	113 - 281	1 - 169
24	5	ASN	ASN	TRP	TRP	(chain Y and (resid 113 through 116 or (resid 117...	Y	X	113 - 281	1 - 169
24	6	ASN	ASN	TRP	TRP	(chain Y and (resid 113 through 116 or (resid 117...	Y	X	113 - 281	1 - 169

Components

#1: Protein

A B C D E F G H I J K L M N O P Q R S ...
Tyrosine-protein phosphatase SIW14

Details:

Mass: 19862.980 Da / Num. of mol.: 24 / Fragment: catalytic core
Source method: isolated from a genetically manipulated source
Source: (gene. exp.) Saccharomyces cerevisiae (brewer's yeast)
Gene: SIW14 / Production host: Escherichia coli (E. coli) / References: UniProt: P53965, protein-tyrosine-phosphatase

#2: Chemical

A-301 B-301 C-301 D-301 E-301 F-301 G-301 H-301 I-301 J-301 K-301 L-301 M-301 N-301 O-301 P-301 Q-301 R-301 S-301 T-301 ...
ChemComp-SO4 / SULFATE ION

Details:

Mass: 96.063 Da / Num. of mol.: 24 / Source method: obtained synthetically / Formula: SO₄

#3: Water

ChemComp-HOH / water

Details:

Mass: 18.015 Da / Num. of mol.: 385 / Source method: isolated from a natural source / Formula: H₂O

Experimental details

Experiment

• Experiment: Method: X-RAY DIFFRACTION / Number of used crystals: 1

Sample preparation

• Crystal: Density Matthews: 2.81 ų/Da / Density % sol: 56.17 %
• Crystal grow: Temperature: 295 K / Method: vapor diffusion, hanging drop / pH: 7.5 ; Details: 0.2 M magnesium chloride, 0.1 M HEPES pH 7.5, 17-25% (w/v) PEG3350

Data collection

• Diffraction: Mean temperature: 100 K / Serial crystal experiment: N
• Diffraction source: Source: SYNCHROTRON / Site: SSRL / Beamline: BL9-2 / Wavelength: 0.97 Å
• Detector: Type: DECTRIS PILATUS 6M / Detector: PIXEL / Date: Feb 17, 2017
• Radiation: Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray
• Radiation wavelength: Wavelength: 0.97 Å / Relative weight: 1
• Reflection twin: Operator: h,-k,-l / Fraction: 0.45
• Reflection: Resolution: 2.5→50 Å / Num. obs: 166746 / % possible obs: 91.3 % / Redundancy: 2.3 % / B_iso Wilson estimate: 37.4 Ų / R_pim(I) all: 0.0105 / R_sym value: 0.0135 / Net I/σ(I): 11.5
• Reflection shell: Resolution: 2.5→2.59 Å / Redundancy: 2 % / Mean I/σ(I) obs: 1.9 / R_pim(I) all: 0.0609 / R_sym value: 0.0788

Processing

Software

Name	Version	Classification
PHENIX	1.14_3260	refinement
PDB_EXTRACT	3.24	data extraction
HKL-2000		data reduction
HKL-2000		data scaling
PHASER		phasing

Refinement

Method to determine structure: MOLECULAR REPLACEMENT
Starting model: 2q47

2q47

Resolution: 2.5→14.995 Å / Cross valid method: THROUGHOUT / σ(F): 232.13 / Phase error: 26.91 / Stereochemistry target values: TWIN_LSQ_F

	Rfactor	Num. reflection	% reflection
Rfree	0.2463	2202	1.35 %
Rwork	0.2298	157333	-
obs	0.2429	163094	90.4 %

• Solvent computation: Shrinkage radii: 0.9 Å / VDW probe radii: 1.11 Å / Solvent model: FLAT BULK SOLVENT MODEL
• Displacement parameters: B_iso max: 164.16 Ų / B_iso mean: 55.5306 Ų / B_iso min: 2 Ų

Refinement step

Cycle: final / Resolution: 2.5→14.995 Å

	Protein	Nucleic acid	Ligand	Solvent	Total
Num. atoms	33542	0	120	385	34047
Biso mean	-	-	47.74	34.38	-
Num. residues	-	-	-	-	4055

Refine LS restraints NCS

Ens-ID	Dom-ID	Auth asym-ID	Number	Refine-ID	Rms	Type
1	1	A	11808	X-RAY DIFFRACTION	2.954	TORSIONAL
1	2	B	11808	X-RAY DIFFRACTION	2.954	TORSIONAL
1	3	C	11808	X-RAY DIFFRACTION	2.954	TORSIONAL
1	4	D	11808	X-RAY DIFFRACTION	2.954	TORSIONAL
1	5	E	11808	X-RAY DIFFRACTION	2.954	TORSIONAL
1	6	F	11808	X-RAY DIFFRACTION	2.954	TORSIONAL
1	7	G	11808	X-RAY DIFFRACTION	2.954	TORSIONAL
1	8	H	11808	X-RAY DIFFRACTION	2.954	TORSIONAL
1	9	I	11808	X-RAY DIFFRACTION	2.954	TORSIONAL
1	10	J	11808	X-RAY DIFFRACTION	2.954	TORSIONAL
1	11	K	11808	X-RAY DIFFRACTION	2.954	TORSIONAL
1	12	L	11808	X-RAY DIFFRACTION	2.954	TORSIONAL
1	13	M	11808	X-RAY DIFFRACTION	2.954	TORSIONAL
1	14	N	11808	X-RAY DIFFRACTION	2.954	TORSIONAL
1	15	O	11808	X-RAY DIFFRACTION	2.954	TORSIONAL
1	16	P	11808	X-RAY DIFFRACTION	2.954	TORSIONAL
1	17	Q	11808	X-RAY DIFFRACTION	2.954	TORSIONAL
1	18	R	11808	X-RAY DIFFRACTION	2.954	TORSIONAL
1	19	S	11808	X-RAY DIFFRACTION	2.954	TORSIONAL
1	20	T	11808	X-RAY DIFFRACTION	2.954	TORSIONAL
1	21	V	11808	X-RAY DIFFRACTION	2.954	TORSIONAL
1	22	W	11808	X-RAY DIFFRACTION	2.954	TORSIONAL
1	23	X	11808	X-RAY DIFFRACTION	2.954	TORSIONAL
1	24	Y	11808	X-RAY DIFFRACTION	2.954	TORSIONAL

LS refinement shell

Refine-ID: X-RAY DIFFRACTION / R_factor R_free error: 0 / Total num. of bins used: 14

Resolution (Å)	Rfactor Rfree	Num. reflection Rfree	Rfactor Rwork	Num. reflection Rwork	Num. reflection all	% reflection obs (%)
2.5073-2.5686	0.3802	188	0.3438	9860	10048	79
2.5686-2.6365	0.3767	106	0.338	11056	11162	88
2.6365-2.7121	0.3616	102	0.3446	11322	11424	90
2.7121-2.7973	0.3141	202	0.3267	11397	11599	91
2.7973-2.8943	0.3607	103	0.3158	11593	11696	92
2.8943-3.0062	0.328	102	0.3042	11562	11664	93
3.0062-3.1379	0.3431	210	0.2933	11201	11411	89
3.1379-3.296	0.2996	114	0.2706	11738	11852	93
3.296-3.4918	0.2731	118	0.2547	11504	11622	92
3.4918-3.7444	0.266	198	0.2339	11367	11565	90
3.7444-4.0908	0.2353	105	0.2188	11147	11252	88
4.0908-4.6159	0.201	198	0.1908	11229	11427	89
4.6159-5.5889	0.2376	85	0.1912	11000	11085	88
5.5889-9.1898	0.1841	164	0.2166	11357	11521	89

Refinement TLS params.

Method: refined / Refine-ID: X-RAY DIFFRACTION

ID	L11 (°2)	L12 (°2)	L13 (°2)	L22 (°2)	L23 (°2)	L33 (°2)	S11 (Å °)	S12 (Å °)	S13 (Å °)	S21 (Å °)	S22 (Å °)	S23 (Å °)	S31 (Å °)	S32 (Å °)	S33 (Å °)	T11 (Å2)	T12 (Å2)	T13 (Å2)	T22 (Å2)	T23 (Å2)	T33 (Å2)	Origin x (Å)	Origin y (Å)	Origin z (Å)
1	0.6761	0.1913	0.2645	0.0992	0.2423	0.8248	-0.0461	0.1096	0.9444	0.1206	-0.3011	0.3598	-0.4668	0.0586	-0.0075	0.3245	-0.0348	-0.0048	0.5418	-0.0734	0.7326	11.0665	20.4489	127.9856
2	0.0421	-0.0783	-0.0378	0.1267	0.09	0.1199	-0.0873	-0.3223	0.9033	0.3414	-0.2904	0.3895	0.2784	0.1841	-0.0004	0.4537	0.0203	0.0227	0.462	0.067	0.7156	21.542	10.6319	131.0088
3	0.704	-0.4765	-1.5184	0.7537	2.209	6.4542	0.3151	0.0754	0.9665	-0.6803	0.0957	-0.377	-1.0997	0.4592	0.4764	0.3064	0.1113	-0.0355	0.3845	0.1368	0.9392	14.0391	19.347	121.3478
4	0.3932	-0.192	0.1343	0.4961	-0.4726	0.4294	-0.0588	0.0691	0.6155	-0.6689	0.0428	-0.5629	-0.0025	-0.1203	0.0018	0.5148	0.0121	0.151	0.3877	0.1365	0.8435	20.1454	11.7794	117.9846
5	0.3471	-0.3553	-0.0032	0.3642	-0.054	0.1103	-0.1325	0.6886	0.3361	-0.3114	-0.1775	-0.2809	0.3697	0.2759	0.0032	0.5118	-0.079	0.1714	0.5431	0.2157	0.8389	21.6438	16.4106	113.0597
6	0.2856	0.0551	-0.6643	1.6792	-0.4788	1.5873	-0.0428	-0.0829	-0.6031	-0.0945	-0.303	-0.119	0.9515	-0.5083	-1.4026	1.2296	0.0688	0.1289	0.4046	0.2621	0.4142	13.9508	-6.8968	116.9062
7	0.1455	-0.0988	-0.129	0.3036	-0.0523	0.2161	0.287	0.6845	0.1907	0.9648	-0.1649	-0.4304	0.2204	0.3935	-0.0043	0.4641	0.0442	0.0212	0.3686	0.0183	0.7687	27.8469	-0.6491	121.7317
8	0.1758	-0.2571	-0.0973	0.4757	0.0196	0.7382	0.0836	-0.3141	1.0056	-0.2405	-0.2053	-0.2133	-0.0957	0.4377	-0.0006	0.3577	0.0125	0.0149	0.5459	0.1593	0.7133	20.6306	8.1227	123.6709
9	0.1209	-0.1045	-0.1081	0.082	0.0918	0.1596	-0.7514	0.567	-0.3192	-0.7364	0.26	-0.46	0.5366	0.4577	-0.0113	0.5654	-0.1368	0.0683	0.4295	0.0514	0.6365	21.449	-0.4436	129.2845
10	3.6218	-3.1185	-0.9853	3.2531	0.6735	0.4002	0.6786	-0.5245	1.0153	-0.0881	0.0206	-0.8885	-0.4346	0.2342	0.2164	1.0417	-0.0496	0.0791	0.352	-0.0019	0.3278	16.6018	-1.3567	136.6987
11	0.6842	-0.2514	0.4431	0.1309	-0.187	0.544	0.3126	0.3591	0.1797	-0.5304	0.1274	0.5212	-0.0193	0.3935	-0.0008	0.4984	-0.0507	0.0455	0.4261	0.0062	0.5827	12.6828	-6.9978	128.621
12	0.0279	0.0147	-0.1998	0.008	-0.1094	1.5495	0.2137	-0.051	-0.6385	-0.1421	-0.3787	-0.3672	0.2306	0.4817	-0.0093	0.6708	0.1414	0.1781	0.4072	0.0975	0.8903	34.4519	-5.3324	128.0523
13	0.4655	-0.5703	0.6051	0.7133	-0.7526	0.7946	-0.0335	-0.0058	-0.231	0.3914	0.6009	-0.0151	-0.3073	-0.2287	0.0481	0.6004	-0.1014	-0.1751	0.5099	-0.0683	1.0417	34.1661	5.684	133.4649
14	0.3912	-0.1113	0.0965	0.679	0.0671	0.5285	0.2645	0.1422	0.0123	-0.4483	-0.2909	0.5523	0.6756	-0.1329	-0.0046	0.6159	0.0879	0.0204	0.4913	0.0096	0.5379	-24.0204	-0.7462	126.9765
15	0.189	0.3458	0.172	0.8071	0.7728	1.4044	-0.1125	-0.2802	0.002	0.1318	0.01	0.097	0.5345	-0.5022	0.1247	0.6606	-0.1153	-0.0649	0.5627	-0.1773	0.1376	-20.9909	13.3932	127.0491
16	0.198	-0.1907	-0.4396	0.2068	0.3619	1.3011	-0.239	0.4408	-0.9148	-0.0145	-0.0757	-0.0724	0.1909	-0.9258	-0.0038	0.5075	-0.0759	0.0852	0.4052	-0.0678	0.423	-24.226	0.911	119.6016
17	0.6509	-0.1078	0.3874	0.1855	-0.1026	0.2386	-0.1585	0.6632	-0.1489	0.1234	-0.2288	0.1999	0.3956	0.0971	-0.0121	0.5749	0.0502	-0.0554	0.4911	-0.0759	0.361	-20.6178	8.9206	115.1425
18	1.2511	-1.0891	1.6193	0.9431	-1.4087	2.1274	0.0896	0.6679	-0.1444	-0.9111	-0.4626	0.0681	0.2604	0.4691	-0.4201	0.4442	-0.0371	-0.0065	0.456	-0.2002	0.7535	-24.7857	6.7119	110.086
19	1.1808	0.2305	0.2584	1.7156	0.6019	0.7089	0.1127	-0.1225	-0.4363	0.8722	-0.2873	-0.8591	0.1752	0.8605	0.0314	0.917	-0.1641	-0.0747	0.8373	0.2504	0.5794	-1.3699	12.6522	113.4871
20	0.1071	0.0191	0.1086	0.0761	-0.0422	0.1381	-0.4978	0.4988	0.0719	-0.7581	-0.0628	-0.359	-0.5273	0.243	-0.0002	0.7732	0.0448	0.0096	0.3543	0.0936	0.5307	-13.1691	22.3297	115.5636
21	0.4015	0.5427	0.1579	0.7279	0.3571	0.4279	0.2374	-0.0168	0.2997	-0.6527	-0.192	0.1879	-0.2168	0.1725	0.0007	0.7928	-0.0599	0.0304	0.3976	-0.0498	0.3332	-17.9894	12.9622	120.1697
22	0.1563	-0.2029	-0.0105	0.2575	0.0232	0.0406	0.3379	0.5942	0.7138	-0.2193	-0.5553	-0.5941	-0.0932	-0.2634	-0.0058	0.4685	0.088	-0.015	0.404	-0.0761	0.4145	-11.2975	18.2399	124.8114
23	0.3149	0.1623	-0.0053	0.2236	0.0754	0.1835	-0.3407	-0.4655	0.2205	0.1605	0.6158	0.305	0.698	0.0948	0.0044	0.655	-0.0331	0.0012	0.3291	-0.0255	0.4573	-8.4919	16.1819	132.9677
24	0.5411	-0.0258	0.0057	0.3118	-0.1225	0.1541	0.4536	0.2478	-0.4601	0.5569	-0.5234	-0.5303	-0.4824	0.3342	0.0014	0.5107	-0.1039	-0.0136	0.6064	0.0841	0.7404	-2.2752	16.8066	124.9869
25	0.2261	-0.0518	-0.2807	0.0823	-0.143	1.0271	-0.1191	0.0684	0.8113	-0.1499	-0.5819	0.0582	-0.188	0.3816	-0.0049	0.9677	-0.0652	-0.2127	0.4134	0.159	0.9555	-15.3457	32.6584	120.6836
26	2.5592	-0.2343	1.2907	0.0205	-0.1233	0.6409	0.2643	-0.6383	-0.011	-0.2888	0.1883	0.1373	-0.7561	-0.3066	0.1327	1.0223	-0.1118	0.11	0.4272	-0.1507	0.634	-23.0176	27.0207	127.3544
27	0.727	-0.1717	0.0114	0.5514	0.6559	0.8634	-0.109	-0.5789	-1.0194	0.358	0.0586	0.0308	-0.024	0.0582	-0.0018	0.3894	0.0004	0.094	0.3687	0.0239	0.5187	7.3524	-23.0328	128.9447
28	0.5431	-0.3344	-0.3018	0.4108	0.1436	0.1381	0.1198	-0.0749	-0.4185	-0.6287	-0.1356	-0.0767	0.1084	-0.1261	-0.0002	0.5487	-0.0461	-0.0007	0.3147	-0.0069	0.6651	4.277	-27.0808	118.0783
29	0.1565	-0.2571	-0.5435	0.4132	1.0643	3.0385	-0.0309	0.1392	-0.0217	-0.2866	0.4012	0.1393	-1.738	0.2579	0.177	0.7967	-0.0487	-0.0727	0.5685	-0.1791	0.7915	-11.6126	-17.3328	116.8611
30	1.1509	-0.5042	-0.811	1.0749	0.4351	1.2684	-0.1096	0.1961	-0.1142	0.1302	0.1279	0.5306	0.1199	-0.1098	-0.001	0.3906	-0.0411	0.0119	0.3994	0.0186	0.6221	-11.4014	-18.603	128.2622
31	0.3085	0.2358	-0.5777	0.7478	-1.0237	2.5445	-0.186	0.2759	-0.5337	-0.0401	0.7564	0.5069	0.6438	-0.369	0.2109	0.7639	0.1176	0.2172	0.494	0.1291	0.7619	-12.9858	-33.3894	133.1986
32	0.0706	0.1243	0.1206	0.7079	-0.4594	0.6041	-0.2076	0.0873	0.1106	-0.6943	0.0836	0.725	-0.0681	-0.3033	-0.0063	0.4686	-0.0173	0.0483	0.3393	0.0411	0.6027	-69.2992	-31.9744	98.4835
33	0.441	0.1231	-0.4048	0.5565	0.0752	0.4079	-0.2708	-0.1845	0.2172	-0.326	-0.0028	-0.2281	-0.0585	-0.0109	0.0003	0.6028	0.0064	0.1187	0.267	-0.0209	0.655	-67.3601	-38.7431	106.192
34	2.8328	-0.5717	0.0232	0.7233	0.5785	0.785	-0.3604	0.1831	0.974	0.1731	0.0007	-0.1402	0.477	0.7857	-0.1241	0.9475	0.0397	0.2934	0.6672	0.072	0.5417	-61.4943	-39.9619	109.8398
35	0.9479	-0.5345	0.2699	0.4985	0.3354	0.818	0.0013	0.0154	-0.2628	0.2347	-0.211	0.0474	0.3776	0.1069	0	0.567	-0.0254	0.1194	0.3358	-0.0569	0.5195	-58.5445	-44.4484	96.2144
36	0.7879	-0.3397	-0.7007	0.5267	-0.0301	0.7036	-0.2208	0.1922	-0.3934	-0.4826	0.2935	-0.1127	0.132	-0.0468	-0.0033	0.7052	-0.1254	0.0124	0.3618	0.0313	0.6831	-56.5901	-50.8727	95.0281
37	1.041	-0.5962	0.237	1.1228	0.6892	0.8222	-0.1197	-0.0192	0.1655	0.1284	0.0641	-0.2172	0.0755	0.0145	0.0001	0.469	-0.0141	0.0775	0.4535	-0.0448	0.3726	-40.4239	-5.0417	104.3584
38	1.2919	-0.614	0.3005	0.6885	-0.1377	0.8759	-0.313	-0.2681	-0.863	0.879	0.2231	-0.0437	0.0615	-0.4587	-0.0058	0.9111	-0.1966	0.1432	0.7073	-0.0897	0.5688	-47.7048	-10.0384	113.6513
39	0.8858	0.4139	0.2632	0.8122	0.4187	1.1835	0.1152	-0.1559	-0.0151	-0.047	-0.1071	0.3146	-0.0551	-0.2958	0.0005	0.49	0.0247	-0.0056	0.3996	-0.0385	0.5092	-57.5215	-7.2032	100.6359
40	0.3711	-0.2856	0.4645	0.4784	-0.426	0.602	-0.0166	-0.2042	-0.4267	0.0617	-0.2619	-0.4505	0.3353	0.0792	-0.0007	0.6433	0.0097	-0.0016	0.4017	0.0381	0.4522	-30.313	-45.093	96.4183
41	1.196	0.8742	-0.1269	1.2068	-0.8769	1.7455	-0.203	-0.204	0.0106	0.2963	-0.4706	0.1673	-0.5922	-0.0606	-0.0127	0.6524	-0.0353	-0.1132	0.5538	0.054	0.4218	-27.4426	-38.6706	108.2137
42	0.4815	0.0595	-0.0885	1.8191	-0.553	1.6001	-0.0428	-0.0112	0.103	0.0472	-0.0637	-0.4466	0.0093	0.2084	-0.0002	0.4494	-0.0883	0.0848	0.505	-0.0283	0.6067	-22.5919	-27.3644	97.8558
43	0.2057	-0.4887	0.1694	1.2737	-0.3147	0.2201	-0.0678	0.2398	0.233	0.202	-0.1084	-0.7116	0.3195	0.0387	-0.0411	0.6994	-0.0853	0.1419	0.5984	-0.0733	0.509	-34.8037	-6.1923	7.8623
44	6.7618	-0.841	5.3765	2.1251	-0.4743	4.7173	-0.3933	0.5631	0.8061	-0.2348	-0.8739	-0.0886	0.0465	0.3773	-1.497	0.0964	-0.0626	0.2098	0.7554	-0.3626	0.8858	-48.5344	-1.9143	5.0379
45	1.3199	-1.4116	0.9353	2.6104	-1.832	1.3084	-0.2731	-0.0457	0.8842	1.0825	-0.0274	-1.1171	-0.3801	0.6397	-0.128	0.5932	-0.0491	0.039	0.6143	-0.0779	0.513	-37.3978	-4.245	14.7941
46	0.6432	-0.4504	0.4234	1.4269	0.0086	0.6285	-0.2846	0.0038	0.0953	0.6301	-0.0487	-0.3006	-0.9046	-0.4878	-0.0785	0.7382	0.1267	0.1019	0.6174	-0.0364	0.3659	-45.3648	-1.0541	20.2435
47	0.7317	0.0697	0.8002	0.7185	-0.1518	1.0846	-0.3402	-0.6124	-0.8371	-0.2353	-0.1943	0.0248	0.8305	-0.1018	0.0192	0.6511	0.0028	0.231	1.1518	-0.2428	0.7895	-59.7939	-17.7685	18.6527
48	1.0871	-0.1342	-0.367	0.106	-0.0478	0.2135	0.0861	0.2036	0.959	-0.2117	0.0092	-0.2585	0.2163	-0.4215	-0.0242	0.4661	-0.1864	0.1017	0.5027	-0.1081	0.5361	-61.7746	-2.9068	14.7554
49	0.4603	-0.0382	0.2862	0.0639	-0.0047	0.3902	0.0252	0.0262	0.3216	0.3604	0.064	0.492	-0.1377	0.3301	0.0007	0.4973	-0.0001	0.144	0.528	-0.0505	0.7399	-50.9375	-3.7095	12.0454
50	0.0754	-0.1003	0.0023	0.1365	-0.0535	0.0997	0.0454	0.2367	0.0597	-0.1854	-0.294	-0.1362	-0.2168	-0.2045	-0.0015	0.7528	0.1677	0.008	0.629	-0.1615	0.4891	-58.128	-7.5626	6.5246
51	0.1973	0.3748	0.0254	0.5816	0.099	0.3358	-0.0152	0.1849	-0.0932	0.0279	0.0678	0.0747	-0.1944	-0.3479	-0.0014	0.3804	-0.0029	0.0654	0.4432	-0.0519	0.6782	-57.8293	-14.9861	2.5334
52	0.1145	-0.1098	0.2418	0.3277	-0.0154	0.7347	-0.6902	0.1042	-0.4053	0.3327	0.0019	0.2433	-0.2781	-0.5588	-0.0188	0.5109	-0.0149	0.0993	0.6239	0.1403	1.3807	-68.7768	1.3064	7.7431
53	0.0002	0.0024	0.0038	0.0012	0.0413	0.0912	0.2845	0.1631	0.3354	-0.3351	-0.0013	0.3506	0.0786	-0.2436	-0.0031	0.6235	0.1573	-0.2286	0.6145	-0.2203	0.9957	-58.9625	6.8458	2.2746
54	1.1577	-0.2844	0.666	0.6651	-0.1689	0.8574	-0.0304	-0.319	-0.4408	0.4607	0.0228	0.3467	-0.252	-0.216	0.0034	0.5927	0.0555	0.0323	0.6078	0.1836	0.543	-31.0725	-42.8186	13.9447
55	0.1724	0.049	-0.146	4.4483	0.6078	0.2241	-0.2454	-0.2614	-0.1546	-0.2749	0.2606	-0.7308	-0.0202	-0.316	0.13	0.8875	-0.175	0.0531	0.6274	0.0816	0.4013	-28.8214	-44.7081	25.0132
56	1.3542	-0.5003	0.1996	0.8695	-0.3096	0.8373	0.6778	-0.7402	1.0186	0.3214	-0.6186	-0.3399	-0.2525	-0.7697	0.0333	0.7012	-0.0143	-0.0272	0.671	-0.0762	0.8154	-28.8438	-23.9359	20.7346
57	0.1763	-0.0968	0.0928	0.5901	-0.0717	0.5773	-0.4655	-0.1543	0.5252	0.1718	0.0012	-0.565	-0.1893	0.4413	0.0013	0.7069	-0.0238	0.0392	0.6324	0.1607	0.4254	-26.7094	-35.6286	15.2161
58	0.4645	-0.133	-0.2655	1.0174	-0.3519	0.4589	-0.2434	-0.1249	0.1658	0.1556	0.1928	0.4025	-0.0547	0.2733	-0.0023	0.7658	-0.133	0.0409	0.4944	0.027	0.4327	-29.8633	-23.8034	6.9848
59	0.1066	0.0502	-0.0661	0.1047	-0.0447	0.1398	-0.2026	0.3227	-0.391	0.4428	0.2119	0.0246	-0.3105	0.4255	-0.0162	0.7404	0.028	-0.0127	0.7142	0.0304	0.9242	-12.7087	-26.3953	12.0311
60	0.1986	0.1865	-0.0426	0.4556	0.0181	0.1464	-0.1003	0.003	-0.2694	0.3654	-0.3572	0.1371	0.3241	-1.0235	-0.0233	0.4303	-0.036	0.035	0.644	-0.0432	0.6964	-71.251	-25.8039	3.7925
61	0.4042	-0.082	-0.0721	0.092	-0.1285	0.2492	0.5178	-0.216	-0.518	-0.4952	-0.7796	0.3712	0.086	-0.0189	-0.0068	0.7552	-0.0401	0.192	0.4901	-0.1547	0.5624	-67.4823	-40.4332	2.8523
62	0.3223	0.4504	-0.1976	1.0063	0.1782	0.4137	0.0108	-0.3806	0.1078	0.2539	-0.1983	0.2762	0.2787	-0.3418	-0.0006	0.5568	-0.0272	0.0368	0.5817	-0.0217	0.4994	-70.9933	-33.0192	12.9991
63	0.4988	0.3431	0.0094	0.5474	-0.1013	0.3761	0.3303	-0.3664	-0.9139	-0.3961	-0.383	-1.0644	0.644	0.4708	-0.0039	0.5925	-0.1007	0.083	0.7365	0.0395	0.6249	-75.2338	-35.4182	19.0665
64	0.2879	0.3749	0.0202	0.4688	0.0455	0.1553	-0.8424	-0.1876	0.0149	0.5518	0.3258	0.065	-0.7157	1.0591	-0.0039	1.1226	-0.1665	-0.2343	0.8416	0.1844	0.7491	-51.0729	-41.1815	20.0493
65	0.2554	-0.2696	-0.0451	0.2487	0.1434	0.3139	0.2255	-0.1197	-0.0819	0.063	0.072	0.3294	0.6606	-0.0212	-0.0044	0.7109	-0.0772	0.0956	0.5628	0.104	0.5207	-62.8489	-45.0584	10.4199
66	0.5473	-0.3369	-0.2097	0.2221	0.02	0.5376	-0.1363	0.4456	-0.1398	0.6775	1.0979	0.0319	0.1568	-0.1267	0.0065	0.6895	0.0784	-0.0008	0.4855	0.0358	0.6323	-53.6825	-42.858	-0.4467
67	0.1315	0.0963	0.1362	0.0971	0.1377	0.269	-0.1513	-0.39	-0.0346	0.1758	-0.0012	-0.6347	-0.3256	-0.5809	-0.0013	0.7052	-0.1046	-0.0325	0.5656	0.0092	0.6816	-48.2371	-41.1544	8.5622
68	0.4408	-0.4022	-0.6597	0.3643	0.5896	0.9554	-0.2525	0.3393	-1.1644	-0.1404	-0.4436	-0.5117	-0.1557	-0.2408	-0.0519	0.9458	-0.2497	-0.0333	0.6057	0.0682	0.9734	-64.2758	-56.8074	5.5739
69	0.6018	-0.2546	0.1342	0.6677	0.1365	0.4514	-0.3536	-0.7231	0.2536	0.71	0.4331	0.0516	-0.087	-0.0779	-0.0043	0.8019	-0.0639	0.1555	0.5127	0.0308	0.412	15.2447	16.5256	36.7027
70	0.0395	0.0989	-0.1654	0.2428	-0.2927	0.7614	-0.4679	0.177	0.279	0.1464	0.1018	0.3544	-1.5522	0.2905	0.0049	0.5502	-0.0659	-0.135	0.5304	0.1298	0.5394	11.7774	20.3723	29.165
71	0.2474	-0.403	0.0525	0.5538	-0.0997	0.2723	0.0015	0.5162	0.1109	-0.6636	0.06	-0.1427	-0.6883	0.3487	0.0102	0.6215	0.0606	0.0491	0.6961	0.0128	0.4757	17.1082	13.1814	25.0604
72	0.1352	0.0722	-0.0666	0.554	0.1606	0.1041	-0.5756	0.1128	-0.2776	-0.6093	0.0651	0.2539	0.2172	-0.3076	-0.0104	0.662	-0.0383	0.0904	0.6307	0.0601	0.4362	17.4201	17.6611	19.721
73	0.9266	0.2854	0.7479	1.2898	-0.5321	1.098	0.5181	-0.192	-0.0837	-0.3218	-0.3286	0.3273	0.4571	-0.8023	1.0381	1.5727	0.3378	-0.1378	0.8487	-0.1136	0.4504	11.0785	-5.7144	24.5396
74	0.4552	-0.6943	0.2618	0.988	-0.3348	0.5054	0.1043	0.1208	0.0346	-0.0635	-0.1479	-0.1628	0.077	0.1371	-0.0008	0.5438	-0.0066	0.0695	0.454	0.0344	0.4678	21.3902	5.604	28.7123
75	0.047	0.1327	-0.0461	0.3506	0.0717	0.3666	-0.0877	0.1159	-0.1237	-0.1216	0.0132	-0.3654	0.148	0.165	0.0001	0.4553	-0.1049	0.0194	0.5038	0.0286	0.468	18.1728	-0.0523	40.3192
76	0.3913	0.4822	-0.054	0.5349	-0.0588	0.7443	0.2683	0.4002	-0.5833	0.1518	-0.088	0.8296	-0.2335	-0.1605	0.0012	0.7036	-0.0632	0.1033	0.4853	-0.0376	0.5494	11.6011	-5.9244	36.1748
77	0.0023	-0.0498	-0.0054	0.457	0.1451	0.3402	0.0678	-0.1336	-0.2301	1.3815	0.2719	-0.7707	0.1858	0.2936	-0.0138	0.9014	-0.0902	0.1971	0.4662	-0.1254	0.704	33.2305	0.3012	34.3474
78	0.3649	-0.0462	0.2027	0.4949	0.2494	0.4393	-0.0448	-0.0638	-0.0665	0.4501	-0.2331	0.0573	0.5352	-0.4691	-0.0065	0.664	0.031	0.0155	0.5209	-0.0121	0.4377	-24.3749	5.3875	38.9651
79	0.5525	0.2676	0.0453	0.5002	-0.0657	0.248	-0.2012	0.1935	-0.3608	0.1215	-0.1744	-0.0349	1.293	-0.1278	0.0128	0.885	-0.0643	-0.0115	0.7349	0.0347	0.3783	-27.0578	9.4844	28.2701
80	1.1671	0.3102	0.6508	0.6241	-0.4324	1.003	0.2772	0.3727	-0.3768	-0.1243	-0.6953	-0.2455	1.1541	0.4024	-0.0235	1.2102	-0.0292	-0.1192	0.5977	0.1349	0.6934	-10.116	18.4461	26.4686
81	0.9516	0.4851	-0.5636	0.9965	-0.2142	1.5001	0.0476	-0.1616	-0.0847	-0.3277	-0.0585	0.0587	-0.1673	0.1293	-0.0002	0.6696	-0.0313	-0.0401	0.4277	0.0148	0.4809	-12.9914	20.2989	38.1634
82	0.6365	0.5699	-0.2168	1.3942	-1.0554	2.7627	0.1665	-0.0203	-0.353	-0.0486	-0.0912	-0.825	0.3994	0.5497	-0.1608	0.8371	-0.0627	0.0359	0.301	-0.1589	0.6807	11.0959	-20.0148	39.1276
83	0.6199	-1.0043	1.4899	1.8189	-2.3852	3.6413	-0.1428	0.0207	-0.8177	0.3097	-0.6309	-0.8754	0.0916	1.2572	-0.4525	0.5323	0.1153	0.1445	0.5531	-0.0397	0.6203	-2.5931	-23.7394	42.0096
84	0.398	0.1873	-0.304	0.5359	0.176	0.4222	0.0353	0.6261	-0.1335	-0.3651	0.0438	-0.1585	0.5752	0.0889	-0.0001	0.5365	-0.0404	0.0866	0.7216	-0.0624	0.4585	3.7943	-22.928	30.8949
85	0.2888	-0.0563	-0.0072	0.1115	0.0766	0.0187	0.2751	0.4749	0.0569	-0.3194	0.1014	-0.2623	-0.0329	0.1556	0.0005	0.6192	-0.0289	0.0774	0.5624	-0.0227	0.5126	2.7478	-27.562	24.5112
86	0.7947	0.3464	0.5218	0.2586	0.4424	0.8823	-0.0542	0.0131	0.3006	-0.3939	-0.1365	0.1896	0.2483	-0.0158	0.0037	0.3562	-0.0649	0.1204	0.7321	-0.0736	0.7143	-10.9676	-18.847	31.6153
87	0.1976	-0.0621	-0.1025	0.0073	0.0237	0.0527	0.2547	0.4989	0.4332	-0.0069	0.326	0.347	-0.1925	-0.2189	-0.0089	0.503	-0.0352	0.0861	0.525	-0.0284	0.5339	-12.2073	-18.4463	39.8239
88	0.1342	-0.159	-0.1412	0.1678	0.1732	0.1865	-0.5229	0.7556	0.1811	0.7739	0.3681	0.3298	0.5621	0.0371	0.0003	0.5433	-0.0373	0.1486	0.6012	0.0035	0.5669	-10.6698	-13.5453	47.1684
89	0.6014	-0.212	-0.4603	0.625	0.3084	0.8915	0.0475	-0.0459	0.2242	-0.1711	-0.166	0.0099	-0.2452	-0.5998	-0.0001	0.617	-0.0566	0.0503	0.6399	-0.0849	0.7181	-17.8583	-16.5991	38.875
90	2.8628	-1.175	0.0516	0.4921	-0.0171	-0.0035	0.2505	0.2967	-1.0067	0.2808	-0.1428	0.1734	0.2261	-0.5668	0.1103	0.8204	0.0682	0.1376	0.633	0.0022	0.4111	-13.4371	-32.4596	45.2767
91	0.8219	0.0288	0.229	0.1272	0.319	0.7308	-0.2568	0.3118	-0.2709	-0.2629	0.3367	0.721	0.042	-0.2402	-0.0013	0.5079	-0.0347	0.0643	0.3484	0.0259	0.6356	-62.8641	-41.271	81.9321
92	0.1204	-0.0295	0.0822	0.1314	0.1435	0.2547	-0.1905	0.1298	-0.3476	1.0912	0.1819	0.3205	-0.2212	-0.34	-0.0025	0.8296	0.0171	0.1064	0.5481	0.0105	0.4128	-60.335	-44.6081	73.9116
93	0.1281	0.0636	0.0161	0.3077	-0.1853	0.0614	0.2601	0.2951	-0.4581	-0.6836	-0.2115	-0.1659	-0.2564	0.2356	0.0109	0.6549	-0.0499	0.0821	0.5043	-0.0782	0.5259	-65.5109	-36.9129	70.7467
94	0.5959	-0.3876	0.0334	0.7224	0.0937	0.7294	0.0982	0.1846	-0.2649	0.4137	0.1474	-0.6432	-0.583	0.15	-0.0177	0.925	0.0872	-0.0417	0.4786	-0.1108	0.5445	-63.0452	-31.2674	67.5947
95	0.2893	-0.1368	0.2605	0.422	0.0496	0.3075	0.1511	0.0818	-0.1098	0.116	-0.0059	0.2573	-0.1357	0.1561	0.0001	0.5421	0.0077	-0.0442	0.3556	-0.0463	0.57	-69.0826	-28.2856	77.2139
96	0.1913	0.0575	-0.1308	0.8134	0.5377	0.8667	0.0917	-0.0045	0.2838	-0.2276	0.0907	0.0422	-0.2609	0.0086	-0.0035	0.6898	0.037	0.0609	0.3459	0.0764	0.5494	-62.8525	-21.4333	86.0059
97	0.0816	-0.0177	0.1071	0.2453	-0.1346	0.2166	0.0179	-0.2565	0.3059	-0.2482	0.1442	1.3156	0.0936	-0.5361	-0.0134	0.7482	-0.0243	-0.11	0.5393	-0.0415	1.0258	-81.8362	-26.4738	82.4702
98	0.1486	-0.3207	-0.1959	0.752	0.1002	0.3365	-0.3772	-0.2017	0.2706	-0.0403	0.0877	-0.424	0.1069	0.2841	-0.003	0.5286	0.0092	0.0154	0.4374	-0.0019	0.4024	-22.8853	-29.5119	80.0253
99	0.6744	0.1708	-0.4165	0.4047	0.0129	0.2692	-0.476	-0.0195	-0.0852	-0.7099	0.325	-0.1251	-0.2498	-0.0218	0	0.6794	-0.1025	0.0889	0.4724	0.0378	0.5227	-22.3839	-32.7934	68.4495
100	0.6015	0.0059	-0.7973	2.0321	-0.2732	1.5577	-0.4126	0.3696	0.1278	-0.0553	0.8071	0.7673	-0.2262	-1.1276	0.0462	1.2085	0.1559	-0.0118	0.7494	0.0105	0.567	-43.9935	-37.6591	68.0831
101	0.3083	0.4367	0.2562	0.522	0.3764	0.2062	0.0899	0.2947	-0.1375	-0.1907	-0.0924	-0.1493	0.099	-0.2119	0	0.6407	0.0543	0.0819	0.4211	-0.047	0.4592	-31.255	-42.3868	75.1709
102	0.1882	0.2321	0.0646	0.3218	0.2572	0.31	0.1856	-0.3091	0.0724	1.006	0.4096	0.2778	-0.3406	0.0791	0.0116	0.6014	-0.0123	0.1202	0.426	0.03	0.3665	-38.4824	-42.1034	87.3865
103	0.7418	0.4868	-0.5703	0.3333	-0.5214	0.9585	-0.0428	-0.2245	-0.0658	0.0521	0.1312	-0.2741	0.285	-0.0166	-0.0013	0.6412	-0.0352	0.0611	0.3269	-0.0025	0.7524	-35.3111	-48.5983	78.4484
104	2.2305	1.547	-0.2303	5.6832	1.3732	1.1759	0.5821	-0.3288	0.376	-0.1659	-0.5101	0.729	-0.1733	-0.7872	0.055	0.8368	0.0033	0.0423	0.6656	-0.1049	0.2384	-58.2432	-4.843	85.9001
105	1.9114	-0.2184	0.4945	1.3197	0.0571	0.1545	-0.6315	0.0053	0.4803	0.166	-0.1802	-0.2607	-0.4315	0.016	-2.8756	0.2595	0.4264	-0.5364	-0.0927	0.8978	-0.0678	-44.4605	-0.8932	87.4752
106	0.0421	0.0371	-0.0143	0.0535	-0.0772	0.177	0.3459	-0.648	0.321	-0.1968	-0.0762	0.6272	-0.2422	-0.166	-0.0002	0.3651	-0.0844	0.0168	0.4573	0.0401	0.5317	-56.7268	-2.3149	79.0747
107	0.4835	0.0883	0.038	0.4805	-0.3682	0.2854	-0.3064	0.1285	0.0379	-0.4752	0.1315	0.2731	0.1074	0.1436	0.0007	0.7573	-0.0461	0.038	0.4288	0.0148	0.4441	-47.5616	-0.2813	75.1761
108	0.7673	-0.1373	0.3326	0.1522	-0.0235	0.9879	0.1814	0.2764	-0.4283	-0.4863	-0.2243	0.1289	-0.1739	0.2663	0.0054	0.7651	0.1197	0.0332	0.6241	0.1505	0.5502	-44.2905	-4.3654	70.8231
109	0.1311	0.0379	0.0126	0.1226	-0.1682	0.2316	-0.6035	0.3703	-0.3299	-0.6684	0.0116	-0.1858	0.0729	0.574	-0.0008	0.6092	-0.0871	0.0991	0.3805	0.0556	0.6448	-32.5335	-0.4055	76.2268
110	1.0243	-0.732	0.0753	0.6012	-0.4486	0.8153	-0.0677	0.2302	-0.2149	0.0821	0.2205	0.0326	0.0524	0.102	-0.0004	0.6112	0.0632	-0.0554	0.3646	0.0337	0.4843	-37.1306	-9.1598	84.7694
111	0.0156	0.0011	-0.1256	-0.001	-0.0107	0.8504	-0.5078	-0.1164	-0.423	0.0984	-0.0325	-0.1883	-0.2692	0.3902	-0.0613	0.5277	-0.2143	0.0357	0.5646	-0.1741	1.1808	-24.7822	2.5536	82.6488
112	0.1196	0.079	0.0712	0.0812	-0.0525	0.231	0.3834	-0.0438	0.716	0.3368	0.2713	-0.8205	-0.4696	-0.1445	0.0094	0.7224	-0.0272	0.1051	0.538	-0.0264	0.6732	-33.7618	7.4576	89.9293
113	0.5399	0.1751	-0.1128	0.4845	0.1605	0.4277	0.117	-0.3429	0.3315	0.4706	-0.2559	-0.1207	0.1279	-0.1277	0.0051	0.7	-0.1074	0.0387	0.6416	-0.1594	0.628	-11.1584	22.6905	51.9231
114	1.0554	1.1495	0.2104	1.388	0.1688	0.5213	-0.08	0.1416	0.1671	-0.4147	0.012	0.1457	-0.3152	-0.0567	-0.0344	0.9381	-0.0797	0.1587	0.6007	-0.0778	0.2862	-22.0515	12.5651	52.8427
115	0.2725	0.1011	-0.1073	0.2721	0.0095	0.4531	-0.6231	0.6307	-0.5224	-0.9624	0.6928	0.3054	-0.4946	0.0396	0.0027	0.61	-0.1621	0.029	0.4378	-0.1194	0.6069	-13.0964	22.5684	59.1996
116	1.5504	1.3855	-0.0702	1.2886	-0.0096	0.0183	-0.034	-0.4021	0.8974	0.3963	0.193	0.3458	-0.5512	0.6499	0.0893	0.5082	0.0745	-0.0193	0.6844	-0.1446	0.4416	-18.0768	15.6489	64.4553
117	0.1102	-0.005	-0.068	0.3531	-0.0278	0.1808	0.0165	-0.4694	-0.0339	0.0836	0.1322	-0.0915	-0.0228	-0.0396	-0.0001	0.7141	0.0276	0.0473	0.4866	0.0028	0.4899	-18.514	21.1395	68.9527
118	3.7379	4.3638	4.965	9.4259	7.9349	7.6772	0.8436	0.388	-0.8135	-0.0466	0.7271	-0.8372	1.3739	0.5608	2.1334	1.2628	-0.3217	0.2549	0.4429	0.1418	0.4921	-11.5822	-2.9081	67.5174
119	0.2838	0.1534	0.0691	0.0968	0.1287	0.4202	-0.1871	0.0548	-0.3623	-0.4496	-0.2128	-0.1439	0.5577	-0.521	0.0029	0.6567	0.0116	0.145	0.5897	0.0607	0.3979	-25.821	2.487	65.2039
120	0.1072	0.248	-0.1661	0.5016	-0.4	0.7463	-0.3312	0.3202	-0.1923	0.2608	-0.1725	0.0559	0.6504	-0.5622	0.0011	0.5381	-0.0265	0.1254	0.5348	-0.0738	0.5403	-20.6682	7.2101	58.3127
121	0.1928	-0.3285	-0.0893	0.5916	-0.051	0.3938	-0.3281	-0.167	-0.2136	-0.6416	0.0861	-0.5308	0.5325	-0.1696	0.0006	0.5658	-0.2023	0.1372	0.6248	0.0372	0.4614	-18.0739	-0.2691	47.9297
122	0.1667	-0.3262	-0.0654	0.6288	-0.029	0.3406	0.2839	-0.3184	0.6143	0.5606	-0.0835	0.0063	0.1816	0.13	-0.0027	0.6782	0.0727	0.091	0.5491	0.0948	0.6121	-15.4311	-4.9579	56.4731
123	0.3047	0.1223	-0.2129	0.061	-0.0181	0.6054	0.2368	0.0921	0.0939	-0.2146	-0.0938	-0.0364	0.0241	-0.308	-0.0016	0.9553	0.1935	0.194	0.6743	0.2041	0.7918	-36.0451	-1.4178	61.0355
124	0.0341	0.0039	-0.0868	0.1139	-0.2139	0.5624	0.0496	0.2378	-0.3105	-0.7491	0.1892	0.6918	0.0956	-0.1735	0.0292	1.0379	0.0267	0.1864	0.809	0.0182	0.4439	-34.7952	7.5534	53.3042
125	1.0302	0.0817	0.5071	0.5434	0.023	0.758	-0.0207	0.0018	-0.012	0.1217	0.0722	0.0186	0.5556	0.0336	-0.0003	0.4684	-0.0168	-0.0844	0.4566	-0.0041	0.4461	23.0702	8.4464	54.5931
126	0.8061	0.2503	-0.1123	0.0774	-0.053	0.0342	-0.3251	-0.3302	-0.7789	0.2408	0.1023	-0.2203	-0.3813	-0.2801	-0.0028	0.7449	-0.078	-0.0168	0.4758	0.0862	0.4661	27.671	11.533	64.3778
127	0.1619	-0.0744	0.3505	2.1882	-2.2232	4.813	0.1603	-0.3584	-0.1811	-0.1978	0.308	1.2282	1.003	-1.5936	0.1084	1.2361	0.1907	-0.0074	0.9144	-0.097	0.8637	3.459	16.8164	63.9467
128	0.4606	-0.0932	-0.3152	0.3489	0.076	0.5036	0.5438	-0.2858	0.3402	-0.6106	-0.2544	-0.9285	0.2305	0.695	0.0066	0.6731	0.1615	0.0512	0.4267	0.0346	0.5852	14.7969	25.8651	58.8184
129	0.6564	-0.6156	0.5607	0.5686	-0.3596	0.7066	-0.0573	0.2461	0.0632	0.2545	0.2064	0.1452	-0.063	-0.2109	-0.0004	0.5104	-0.0226	0.0607	0.4815	0.0124	0.4871	9.5605	17.396	50.2655
130	0.0263	0.0804	0.0766	0.1765	0.2076	0.2309	0.0251	0.5646	0.5735	0.6032	0.0992	-0.2959	-0.3204	-0.0682	-0.0145	0.8484	0.0433	0.0515	0.5014	0.0343	0.7876	17.2067	31.6786	49.2468
131	0.5301	-0.5219	-0.071	0.4964	-0.1601	0.5046	-0.1219	0.3199	-0.1869	-0.1972	0.1733	0.2739	-0.1542	-0.2872	-0.0008	0.7347	0.0159	0.1299	0.5987	0.0609	0.345	-5.4082	-21.0624	53.6005
132	0.0887	-0.1891	0.1196	0.2586	-0.2762	0.2027	0.021	-0.1881	-0.365	0.4485	-0.0772	0.2366	0.2266	-0.1023	-0.0001	0.5953	-0.08	0.0115	0.5068	0.0405	0.4239	-4.3681	-21.8908	65.7856
133	1.6952	0.2906	-0.7565	0.4806	0.5052	1.259	0.0328	0.6123	0.4746	0.0425	0.0485	-0.1405	-0.9974	-0.2947	-0.0147	1.0331	-0.1461	-0.0875	1.1589	0.1568	0.2323	12.8215	-6.1002	64.4366
134	0.657	-0.0281	0.2976	0.1499	0.0421	0.3623	0.0658	-0.1569	-0.1189	0.2331	-0.3004	-0.7189	-0.073	0.1978	0.001	0.5448	-0.0028	0.0396	0.4073	0.0354	0.4296	8.9768	-19.7179	58.3883
135	1.1968	0.8023	0.1466	1.0268	-0.6326	1.3468	-0.1695	-0.1338	-0.0368	0.3135	0.6409	-0.1634	0.0373	0.2927	0.0048	0.5385	-0.0392	0.0336	0.5345	-0.0065	0.4141	13.5715	-17.4552	50.8461
136	0.6832	-0.0938	-0.2168	1.0093	-0.1081	0.7297	-0.6978	-0.3243	0.4167	0.3196	0.2874	-0.7981	-0.1236	0.2487	-0.1111	0.5806	0.0758	-0.1788	0.4967	-0.2309	0.8657	21.9951	7.3178	146.6578
137	0.2061	0.0634	0.1088	0.3417	0.0442	0.1342	-0.09	-0.4478	-0.2659	0.4951	0.3298	-0.2414	0.2208	-0.2185	1.4933	1.3654	0.71	-0.49	0.6731	-0.7213	0.9168	12.066	15.5121	156.2881
138	0.7151	-0.1874	-0.0465	0.3722	-0.8287	1.9077	-0.6288	-0.3384	0.5802	0.2672	0.5702	-0.3632	0.0619	-0.3393	0.1072	0.6544	0.1742	-0.1295	0.4529	-0.222	0.6165	7.7778	16.586	141.6621
139	0.3089	-0.0939	0.2026	0.1327	0.0324	0.1425	-0.1446	1.258	0.2668	0.4681	-0.2925	0.3875	0.504	0.1905	-0.0209	0.9727	0.1096	-0.2168	0.725	-0.2044	1.0694	15.1212	30.845	141.9602
140	0.2565	-0.8806	-0.1066	3.0915	0.3438	0.0602	-0.6406	0.086	-0.2493	0.1125	0.2534	1.6482	-0.1778	0.1659	-0.0465	0.6464	-0.0407	0.1374	0.4883	0.1144	0.6102	-13.8818	-19.7674	142.3966
141	0.3399	-0.0803	-0.4465	0.4281	0.2881	0.8376	-0.5759	0.2643	-0.1142	0.0555	0.4044	0.6595	-0.031	-0.6746	-0.6786	0.5074	0.0706	0.4099	0.7791	0.3888	0.6476	-7.8191	-22.1235	146.9379
142	1.2383	1.236	0.634	3.1007	1.0241	1.224	-0.0327	-0.541	-0.9627	0.7804	0.5816	-0.5414	-0.2245	0.3193	0.2111	0.3952	0.0861	0.1594	0.7737	0.249	0.6752	-4.7311	-22.1157	154.7336
143	0.569	-0.1524	0.2905	0.4145	-0.2548	0.4143	-0.3236	-0.0705	-0.0167	0.0401	0.1326	-0.1641	-0.147	-0.1104	-0.3685	0.8707	0.9285	0.4097	1.238	0.659	0.9982	-8.8398	-24.4173	159.5553
144	0.2208	-0.2108	-0.0403	0.6754	-0.346	0.31	-0.0681	-0.2257	0.7227	-0.2268	-0.2926	0.7274	-0.8207	0.1558	-0.0129	1.0722	0.0623	0.0336	0.9821	0.1368	0.9	8.4496	-6.9299	157.3198
145	0.497	-0.4694	-0.3458	0.4545	0.3263	0.2496	0.1218	-0.3713	0.2527	-0.3357	0.0986	-0.8617	0.0599	0.6661	0.0208	0.8524	0.2522	-0.0029	0.7218	0.0666	0.4593	10.7899	-21.8767	155.1324
146	0.5802	0.2991	0.092	0.8484	0.0868	0.6783	-0.3736	-0.4356	-0.0984	0.5734	0.6095	-0.1046	0.1595	-0.3784	0.011	0.5387	0.2523	0.1756	0.6903	0.2243	0.5343	0.6233	-21.4053	150.0235
147	0.0072	0.0203	-0.0357	0.0934	-0.3311	1.1807	-0.2425	0.0784	0.9928	0.2621	-0.3407	-0.0004	-0.1264	0.3003	-0.2021	0.7125	0.1943	0.0892	0.3398	-0.0787	0.5955	8.9121	-18.038	145.8669
148	0.6557	0.8129	-0.2721	0.9118	-0.2913	0.4566	-0.2265	-0.3668	0.2653	0.7679	0.0753	0.3843	-0.3596	0.2515	-0.0023	0.6342	0.0442	0.0789	0.4641	-0.0383	0.4145	9.6311	-11.0849	141.3333
149	0.2171	-0.1727	0.0441	0.1823	-0.1042	0.1214	-0.1619	-0.4017	-0.3762	0.049	-0.3354	-0.3103	1.0812	0.4859	0.0084	0.6904	0.165	0.0388	0.7036	0.1033	0.8443	18.7428	-26.2749	150.2914
150	0.5588	0.658	1.4723	0.7756	1.7215	3.8296	-0.1588	-0.1696	-0.6705	-0.0821	0.9865	-0.3597	0.8486	0.642	0.2253	0.5932	-0.0265	0.1603	0.9774	-0.046	0.5947	10.4635	-32.8201	143.3495
151	0.8604	-0.0591	-0.252	0.3885	0.4397	0.8339	-0.5806	0.0525	0.1545	0.2811	0.1886	-0.3311	0.0112	-0.2675	-0.0243	0.6357	0.1149	0.119	0.5155	-0.0596	0.5293	-18.1004	16.4778	138.6251
152	0.0947	-0.0257	-0.1048	0.1043	0.0659	0.117	0.0921	-0.8552	0.866	0.1483	0.1721	0.083	-0.4696	0.0049	0.0166	0.635	0.0674	-0.1189	0.5488	-0.1028	0.5446	-16.3914	21.5068	146.0212
153	0.2975	-0.4666	-0.2831	1.839	0.441	0.2609	-0.6031	-1.0076	-0.1894	1.1071	0.3097	-0.0681	0.0865	-0.0945	-1.2631	0.3021	0.3969	-0.267	0.8001	0.0676	0.4805	-22.4515	14.6726	150.285
154	0.5849	-0.332	0.2353	0.193	-0.0429	0.6888	-0.288	-0.7833	0.2044	0.0801	0.2127	-0.0568	-0.4875	-0.0999	0.0022	0.761	0.3188	-0.1015	0.8224	-0.0238	0.4255	-23.779	20.226	154.3679
155	0.011	-0.0787	-0.0402	0.5075	0.2719	0.1792	0.1748	-1.1591	-0.6073	0.09	-0.1772	-0.2059	0.5721	0.8704	0.0142	0.8795	0.0553	0.2668	1.2862	0.381	0.9733	-22.4287	-1.2024	152.6175
156	0.0821	0.0932	0.025	0.2969	0.3211	0.3221	0.1882	-0.4411	-0.2164	0.2983	-0.141	0.2922	0.7533	-0.2286	-0.0029	0.5197	0.0516	0.0426	0.5635	-0.0121	0.5448	-23.5706	6.1883	143.7538
157	0.8648	-0.0107	-0.0198	0.3742	0.0544	0.1139	0.3966	0.4769	-0.6869	0.3903	-0.2069	-0.1243	-0.3487	-0.3765	0.0236	0.5183	0.0301	0.1826	0.5415	0.0816	0.689	-18.7882	-1.3703	134.3112
158	0.4656	-0.277	0.4527	0.7169	0.3128	0.9876	0.433	-0.4087	0.1343	0.5322	0.4486	0.1896	0.6704	-0.3165	0.0441	0.8763	0.0904	0.1832	0.5845	0.1733	0.7494	-17.8596	-5.9765	143.2599
159	0.1569	-0.1226	-0.328	3.6638	1.1422	0.833	0.2919	-1.1416	-0.7936	-0.6757	-0.2865	0.5208	0.1254	-0.563	0.0291	0.3861	0.0582	-0.0208	1.0201	0.0672	0.7708	-37.4633	1.6662	139.0262
160	0.3566	0.0599	0.0924	0.8444	0.1164	0.3274	-0.2646	0.0412	-0.176	0.5378	-0.13	0.1996	-0.3433	-0.0659	-0.0532	1.285	-0.0399	-0.1227	0.4309	-0.1691	1.8109	-60.994	-5.281	173.2831
161	0.118	-0.1085	0.0965	0.109	-0.0907	0.0661	-0.6331	-0.4284	-0.3456	0.8444	-0.1124	-0.1109	-0.4293	0.4435	-0.0018	0.7918	-0.07	-0.117	0.556	0.0907	0.931	-46.692	-1.5023	172.6245
162	0.7099	0.331	0.2618	0.2324	-0.0501	0.7854	-0.2923	0.5156	0.0848	0.2286	0.4006	-0.6628	-0.8782	-0.6508	0.0038	0.647	0.1338	0.0983	0.7425	0.1319	0.6853	-59.8566	-4.0583	166.1081
163	0.3983	0.0662	-0.1405	0.3327	0.1165	0.4388	0.3511	0.3086	0.3089	-0.0601	0.3223	-0.705	0.0503	0.3556	0.0096	0.873	0.002	0.0684	0.7753	-0.1404	0.4581	-51.5376	-3.2483	160.8609
164	0.0392	-0.0921	0.0491	0.2131	0.025	0.2679	0.2356	1.3007	0.7319	-0.4465	-0.1791	-0.0492	0.7021	0.1278	0.0016	0.9136	0.068	0.0303	0.7385	-0.0544	0.7604	-55.8359	-0.0131	156.1542
165	0.1293	-0.0405	0.149	0.3421	-0.1909	0.2644	-0.4896	0.3417	-0.3837	0.0081	-0.3148	0.1208	1.2701	-0.2202	-0.0031	1.3193	0.3723	0.2784	1.6509	0.273	1.1399	-38.3962	-17.7502	157.7896
166	0.3636	0.1255	0.1354	0.1398	-0.1168	0.3044	0.2669	0.5242	-0.0751	-0.025	0.3221	0.0144	-0.316	0.0498	-0.0009	0.9913	0.1258	-0.0129	0.9308	0.0714	0.6642	-36.5109	-2.08	160.798
167	0.0423	-0.1104	-0.0017	0.4218	-0.0541	0.9288	-0.0553	-0.7456	-0.299	-0.1782	0.4246	-1.3302	0.4403	1.2418	0.0707	0.6738	-0.0627	-0.0999	0.669	-0.2094	1.2028	-46.8278	-4.2919	165.5179
168	1.094	0.3824	0.5339	0.1867	0.1643	0.3643	-0.834	0.5643	-1.2298	0.5534	1.0583	0.1773	0.2793	0.1216	0.017	0.9829	0.0561	0.1275	0.5981	0.057	0.8176	-37.6193	-9.7657	174.5235
169	0.2669	0.0039	-0.1282	0.1091	0.2896	0.7499	0.2058	-0.8558	0.0529	-0.1318	0.6935	-0.5487	-0.6468	-0.4246	0.0423	0.6855	0.0916	-0.0328	0.5577	0.0832	1.1587	-36.3961	-17.9491	169.7172
170	0.4369	0.1751	-0.2229	0.1603	-0.2562	0.4231	0.1043	0.4244	0.465	1.201	0.114	-0.0376	-0.2254	0.2723	-0.0214	1.2076	-0.233	0.1827	0.7985	-0.1458	0.8501	-30.988	3.5943	167.8287
171	1.0769	-0.0393	-0.0403	0.0567	0.1567	0.3989	-0.0959	0.2118	-0.9439	-0.2885	-0.3289	-0.3504	-0.173	0.5061	0.0117	0.6913	0.1429	-0.0141	0.6397	0.0154	0.5414	-59.5013	-46.6378	175.0886
172	0.9938	-0.3869	-0.1061	0.8079	0.0986	0.1192	0.7273	0.4133	-1.1617	0.4513	-0.237	-0.5745	0.2855	0.1347	0.1164	0.5258	0.1833	-0.1364	0.5481	-0.2628	0.7495	-65.6705	-42.2221	172.1311
173	0.7189	-0.2942	1.1204	1.1397	-0.671	2.8088	-0.1044	0.8354	-0.1548	-0.614	-0.487	-0.1007	-0.2661	0.0448	-3.0567	0.8453	0.4251	-0.0483	0.9604	-0.294	0.1386	-68.8326	-39.2777	165.0359
174	0.298	-0.005	0.4141	0.4523	0.2085	0.6857	0.169	0.2912	0.1765	-0.0369	-0.5951	0.2255	0.3772	-0.1144	-0.838	0.5718	0.1868	0.1003	1.3185	-0.3907	0.4803	-70.5136	-44.2315	160.5329
175	2.0435	-0.5721	-0.7852	2.1573	0.9088	0.5396	0.0178	-0.1202	0.5716	-0.0298	-0.1394	-0.3983	-0.7749	0.05	0.5258	1.7056	0.4141	-0.3618	1.4374	0.2807	0.7267	-63.4092	-20.666	161.4076
176	1.6722	0.3636	0.3887	0.5806	-0.0997	0.4773	-0.5267	0.5268	1.1064	0.0825	0.2712	0.3025	0.2191	0.1322	-0.0312	0.4954	0.1825	0.0403	0.6708	-0.0468	0.7015	-73.0231	-31.3626	168.8727
177	1.0521	0.4251	0.038	0.224	-0.0283	0.3637	0.5477	0.1328	1.5713	-0.1183	-0.4823	-0.3159	-0.1411	-0.157	-0.0092	0.5934	0.0485	0.1538	0.4437	0.0215	0.7214	-66.8443	-24.8296	179.2074
178	0.0792	0.1438	0.1664	0.2034	0.268	0.2304	0.5569	-0.2338	0.3906	0.2002	0.0023	0.0386	-0.2238	-0.149	0.002	1.0007	0.0771	0.2136	0.5584	0.1141	1.2368	-71.7323	-20.2439	172.8822
179	0.0117	0.0672	-0.0115	0.3192	0.0336	0.5269	1.1109	0.2974	0.4787	0.1242	-0.1245	0.4637	-0.7634	0.0952	0.1972	0.6105	0.092	-0.0239	0.6243	0.2677	0.6115	-82.5243	-31.6361	180.2459
180	0.8935	-0.3158	-0.5568	1.8789	-0.4634	1.0734	-0.0385	0.3526	0.5796	0.5566	0.0092	-0.2391	-0.2004	0.4451	-0.2194	0.7053	0.2784	0.1461	0.8537	-0.0757	-0.0885	-25.9594	-32.3421	171.5825
181	0.0964	0.096	0.087	0.1319	0.1282	0.1549	-0.1706	0.1578	0.018	-0.1734	-0.0141	-0.0243	-0.5844	-0.1844	-0.2131	0.7959	0.4415	0.0888	1.2803	0.55	0.1524	-24.4037	-28.0861	163.8647
182	0.1886	-0.0613	0.1467	0.3523	-0.1444	0.1208	0.4489	0.8299	0.332	-0.3399	-0.3486	-0.1044	-0.5705	-0.5155	-0.0005	0.624	0.1147	0.0504	1.0759	-0.0011	0.4778	-26.2869	-36.1446	157.525
183	0.94	0.0845	-0.2025	0.3341	-0.0488	0.2127	-0.0731	0.6071	-0.0417	0.0066	0.2298	-0.07	0.1563	0.2807	0.2673	1.3694	0.5902	-0.277	1.3176	-0.1844	0.2475	-47.6921	-40.9939	160.272
184	1.8014	-0.2559	0.249	0.4735	-0.4179	0.493	0.316	1.3162	-0.9302	0.2983	0.0261	0.3536	0.5904	-0.3663	0.3529	0.4892	0.1832	-0.0139	0.7745	-0.3101	0.6308	-33.9183	-43.9799	166.7352
185	0.4035	-0.2583	-0.4661	0.7905	0.1913	1.1424	0.3616	-0.1006	-0.091	-0.9873	0.1858	-0.1842	-0.7235	-0.4332	0.0718	0.4511	0.1008	-0.0106	0.5248	0.0509	0.5825	-43.2133	-41.0695	175.9281
186	0.0966	0.0842	0.0166	0.0863	-0.0591	0.2568	0.2676	-0.1483	-0.8641	-0.0939	-0.3038	-0.3261	0.4199	-0.3585	-0.0228	0.8192	0.1004	0.0828	0.6192	-0.2912	0.8816	-31.0933	-56.1882	171.4188

Refinement TLS group

ID	Refine-ID	Refine TLS-ID	Selection details	Auth asym-ID	Auth seq-ID
1	X-RAY DIFFRACTION	1	chain 'A' and (resid 113 through 122 )	A	113 - 122
2	X-RAY DIFFRACTION	2	chain 'A' and (resid 123 through 132 )	A	123 - 132
3	X-RAY DIFFRACTION	3	chain 'A' and (resid 133 through 145 )	A	133 - 145
4	X-RAY DIFFRACTION	4	chain 'A' and (resid 146 through 161 )	A	146 - 161
5	X-RAY DIFFRACTION	5	chain 'A' and (resid 162 through 177 )	A	162 - 177
6	X-RAY DIFFRACTION	6	chain 'A' and (resid 178 through 191 )	A	178 - 191
7	X-RAY DIFFRACTION	7	chain 'A' and (resid 192 through 203 )	A	192 - 203
8	X-RAY DIFFRACTION	8	chain 'A' and (resid 204 through 219 )	A	204 - 219
9	X-RAY DIFFRACTION	9	chain 'A' and (resid 220 through 231 )	A	220 - 231
10	X-RAY DIFFRACTION	10	chain 'A' and (resid 232 through 247 )	A	232 - 247
11	X-RAY DIFFRACTION	11	chain 'A' and (resid 248 through 261 )	A	248 - 261
12	X-RAY DIFFRACTION	12	chain 'A' and (resid 262 through 273 )	A	262 - 273
13	X-RAY DIFFRACTION	13	chain 'A' and (resid 274 through 281 )	A	274 - 281
14	X-RAY DIFFRACTION	14	chain 'B' and (resid 113 through 122 )	B	113 - 122
15	X-RAY DIFFRACTION	15	chain 'B' and (resid 123 through 132 )	B	123 - 132
16	X-RAY DIFFRACTION	16	chain 'B' and (resid 133 through 145 )	B	133 - 145
17	X-RAY DIFFRACTION	17	chain 'B' and (resid 146 through 161 )	B	146 - 161
18	X-RAY DIFFRACTION	18	chain 'B' and (resid 162 through 177 )	B	162 - 177
19	X-RAY DIFFRACTION	19	chain 'B' and (resid 178 through 191 )	B	178 - 191
20	X-RAY DIFFRACTION	20	chain 'B' and (resid 192 through 202 )	B	192 - 202
21	X-RAY DIFFRACTION	21	chain 'B' and (resid 203 through 219 )	B	203 - 219
22	X-RAY DIFFRACTION	22	chain 'B' and (resid 220 through 231 )	B	220 - 231
23	X-RAY DIFFRACTION	23	chain 'B' and (resid 232 through 247 )	B	232 - 247
24	X-RAY DIFFRACTION	24	chain 'B' and (resid 248 through 264 )	B	248 - 264
25	X-RAY DIFFRACTION	25	chain 'B' and (resid 265 through 273 )	B	265 - 273
26	X-RAY DIFFRACTION	26	chain 'B' and (resid 274 through 281 )	B	274 - 281
27	X-RAY DIFFRACTION	27	chain 'C' and (resid 113 through 145 )	C	113 - 145
28	X-RAY DIFFRACTION	28	chain 'C' and (resid 146 through 177 )	C	146 - 177
29	X-RAY DIFFRACTION	29	chain 'C' and (resid 178 through 202 )	C	178 - 202
30	X-RAY DIFFRACTION	30	chain 'C' and (resid 203 through 273 )	C	203 - 273
31	X-RAY DIFFRACTION	31	chain 'C' and (resid 274 through 281 )	C	274 - 281
32	X-RAY DIFFRACTION	32	chain 'D' and (resid 113 through 145 )	D	113 - 145
33	X-RAY DIFFRACTION	33	chain 'D' and (resid 146 through 161 )	D	146 - 161
34	X-RAY DIFFRACTION	34	chain 'D' and (resid 162 through 191 )	D	162 - 191
35	X-RAY DIFFRACTION	35	chain 'D' and (resid 192 through 247 )	D	192 - 247
36	X-RAY DIFFRACTION	36	chain 'D' and (resid 248 through 281 )	D	248 - 281
37	X-RAY DIFFRACTION	37	chain 'E' and (resid 113 through 161 )	E	113 - 161
38	X-RAY DIFFRACTION	38	chain 'E' and (resid 162 through 191 )	E	162 - 191
39	X-RAY DIFFRACTION	39	chain 'E' and (resid 192 through 281 )	E	192 - 281
40	X-RAY DIFFRACTION	40	chain 'F' and (resid 113 through 145 )	F	113 - 145
41	X-RAY DIFFRACTION	41	chain 'F' and (resid 146 through 191 )	F	146 - 191
42	X-RAY DIFFRACTION	42	chain 'F' and (resid 192 through 281 )	F	192 - 281
43	X-RAY DIFFRACTION	43	chain 'G' and (resid 113 through 122 )	G	113 - 122
44	X-RAY DIFFRACTION	44	chain 'G' and (resid 123 through 132 )	G	123 - 132
45	X-RAY DIFFRACTION	45	chain 'G' and (resid 133 through 145 )	G	133 - 145
46	X-RAY DIFFRACTION	46	chain 'G' and (resid 146 through 177 )	G	146 - 177
47	X-RAY DIFFRACTION	47	chain 'G' and (resid 178 through 191 )	G	178 - 191
48	X-RAY DIFFRACTION	48	chain 'G' and (resid 192 through 202 )	G	192 - 202
49	X-RAY DIFFRACTION	49	chain 'G' and (resid 203 through 219 )	G	203 - 219
50	X-RAY DIFFRACTION	50	chain 'G' and (resid 220 through 231 )	G	220 - 231
51	X-RAY DIFFRACTION	51	chain 'G' and (resid 232 through 261 )	G	232 - 261
52	X-RAY DIFFRACTION	52	chain 'G' and (resid 262 through 273 )	G	262 - 273
53	X-RAY DIFFRACTION	53	chain 'G' and (resid 274 through 281 )	G	274 - 281
54	X-RAY DIFFRACTION	54	chain 'H' and (resid 113 through 161 )	H	113 - 161
55	X-RAY DIFFRACTION	55	chain 'H' and (resid 162 through 177 )	H	162 - 177
56	X-RAY DIFFRACTION	56	chain 'H' and (resid 178 through 203 )	H	178 - 203
57	X-RAY DIFFRACTION	57	chain 'H' and (resid 204 through 219 )	H	204 - 219
58	X-RAY DIFFRACTION	58	chain 'H' and (resid 220 through 261 )	H	220 - 261
59	X-RAY DIFFRACTION	59	chain 'H' and (resid 262 through 281 )	H	262 - 281
60	X-RAY DIFFRACTION	60	chain 'I' and (resid 113 through 122 )	I	113 - 122
61	X-RAY DIFFRACTION	61	chain 'I' and (resid 123 through 132 )	I	123 - 132
62	X-RAY DIFFRACTION	62	chain 'I' and (resid 133 through 161 )	I	133 - 161
63	X-RAY DIFFRACTION	63	chain 'I' and (resid 162 through 177 )	I	162 - 177
64	X-RAY DIFFRACTION	64	chain 'I' and (resid 178 through 191 )	I	178 - 191
65	X-RAY DIFFRACTION	65	chain 'I' and (resid 192 through 231 )	I	192 - 231
66	X-RAY DIFFRACTION	66	chain 'I' and (resid 232 through 247 )	I	232 - 247
67	X-RAY DIFFRACTION	67	chain 'I' and (resid 248 through 261 )	I	248 - 261
68	X-RAY DIFFRACTION	68	chain 'I' and (resid 262 through 281 )	I	262 - 281
69	X-RAY DIFFRACTION	69	chain 'J' and (resid 113 through 132 )	J	113 - 132
70	X-RAY DIFFRACTION	70	chain 'J' and (resid 133 through 145 )	J	133 - 145
71	X-RAY DIFFRACTION	71	chain 'J' and (resid 146 through 161 )	J	146 - 161
72	X-RAY DIFFRACTION	72	chain 'J' and (resid 162 through 177 )	J	162 - 177
73	X-RAY DIFFRACTION	73	chain 'J' and (resid 178 through 191 )	J	178 - 191
74	X-RAY DIFFRACTION	74	chain 'J' and (resid 192 through 219 )	J	192 - 219
75	X-RAY DIFFRACTION	75	chain 'J' and (resid 220 through 247 )	J	220 - 247
76	X-RAY DIFFRACTION	76	chain 'J' and (resid 248 through 261 )	J	248 - 261
77	X-RAY DIFFRACTION	77	chain 'J' and (resid 262 through 281 )	J	262 - 281
78	X-RAY DIFFRACTION	78	chain 'K' and (resid 113 through 144 )	K	113 - 144
79	X-RAY DIFFRACTION	79	chain 'K' and (resid 145 through 177 )	K	145 - 177
80	X-RAY DIFFRACTION	80	chain 'K' and (resid 178 through 202 )	K	178 - 202
81	X-RAY DIFFRACTION	81	chain 'K' and (resid 203 through 281 )	K	203 - 281
82	X-RAY DIFFRACTION	82	chain 'L' and (resid 113 through 122 )	L	113 - 122
83	X-RAY DIFFRACTION	83	chain 'L' and (resid 123 through 132 )	L	123 - 132
84	X-RAY DIFFRACTION	84	chain 'L' and (resid 133 through 161 )	L	133 - 161
85	X-RAY DIFFRACTION	85	chain 'L' and (resid 162 through 177 )	L	162 - 177
86	X-RAY DIFFRACTION	86	chain 'L' and (resid 178 through 219 )	L	178 - 219
87	X-RAY DIFFRACTION	87	chain 'L' and (resid 220 through 231 )	L	220 - 231
88	X-RAY DIFFRACTION	88	chain 'L' and (resid 232 through 247 )	L	232 - 247
89	X-RAY DIFFRACTION	89	chain 'L' and (resid 248 through 273 )	L	248 - 273
90	X-RAY DIFFRACTION	90	chain 'L' and (resid 274 through 281 )	L	274 - 281
91	X-RAY DIFFRACTION	91	chain 'M' and (resid 113 through 132 )	M	113 - 132
92	X-RAY DIFFRACTION	92	chain 'M' and (resid 133 through 145 )	M	133 - 145
93	X-RAY DIFFRACTION	93	chain 'M' and (resid 146 through 161 )	M	146 - 161
94	X-RAY DIFFRACTION	94	chain 'M' and (resid 162 through 191 )	M	162 - 191
95	X-RAY DIFFRACTION	95	chain 'M' and (resid 192 through 231 )	M	192 - 231
96	X-RAY DIFFRACTION	96	chain 'M' and (resid 232 through 264 )	M	232 - 264
97	X-RAY DIFFRACTION	97	chain 'M' and (resid 265 through 281 )	M	265 - 281
98	X-RAY DIFFRACTION	98	chain 'N' and (resid 113 through 145 )	N	113 - 145
99	X-RAY DIFFRACTION	99	chain 'N' and (resid 146 through 177 )	N	146 - 177
100	X-RAY DIFFRACTION	100	chain 'N' and (resid 178 through 191 )	N	178 - 191
101	X-RAY DIFFRACTION	101	chain 'N' and (resid 192 through 231 )	N	192 - 231
102	X-RAY DIFFRACTION	102	chain 'N' and (resid 232 through 247 )	N	232 - 247
103	X-RAY DIFFRACTION	103	chain 'N' and (resid 248 through 281 )	N	248 - 281
104	X-RAY DIFFRACTION	104	chain 'O' and (resid 113 through 122 )	O	113 - 122
105	X-RAY DIFFRACTION	105	chain 'O' and (resid 123 through 132 )	O	123 - 132
106	X-RAY DIFFRACTION	106	chain 'O' and (resid 133 through 145 )	O	133 - 145
107	X-RAY DIFFRACTION	107	chain 'O' and (resid 146 through 161 )	O	146 - 161
108	X-RAY DIFFRACTION	108	chain 'O' and (resid 162 through 191 )	O	162 - 191
109	X-RAY DIFFRACTION	109	chain 'O' and (resid 192 through 202 )	O	192 - 202
110	X-RAY DIFFRACTION	110	chain 'O' and (resid 203 through 261 )	O	203 - 261
111	X-RAY DIFFRACTION	111	chain 'O' and (resid 262 through 273 )	O	262 - 273
112	X-RAY DIFFRACTION	112	chain 'O' and (resid 274 through 281 )	O	274 - 281
113	X-RAY DIFFRACTION	113	chain 'P' and (resid 113 through 122 )	P	113 - 122
114	X-RAY DIFFRACTION	114	chain 'P' and (resid 123 through 132 )	P	123 - 132
115	X-RAY DIFFRACTION	115	chain 'P' and (resid 133 through 145 )	P	133 - 145
116	X-RAY DIFFRACTION	116	chain 'P' and (resid 146 through 161 )	P	146 - 161
117	X-RAY DIFFRACTION	117	chain 'P' and (resid 162 through 177 )	P	162 - 177
118	X-RAY DIFFRACTION	118	chain 'P' and (resid 178 through 191 )	P	178 - 191
119	X-RAY DIFFRACTION	119	chain 'P' and (resid 192 through 202 )	P	192 - 202
120	X-RAY DIFFRACTION	120	chain 'P' and (resid 203 through 231 )	P	203 - 231
121	X-RAY DIFFRACTION	121	chain 'P' and (resid 232 through 247 )	P	232 - 247
122	X-RAY DIFFRACTION	122	chain 'P' and (resid 248 through 264 )	P	248 - 264
123	X-RAY DIFFRACTION	123	chain 'P' and (resid 265 through 273 )	P	265 - 273
124	X-RAY DIFFRACTION	124	chain 'P' and (resid 274 through 281 )	P	274 - 281
125	X-RAY DIFFRACTION	125	chain 'Q' and (resid 113 through 161 )	Q	113 - 161
126	X-RAY DIFFRACTION	126	chain 'Q' and (resid 162 through 177 )	Q	162 - 177
127	X-RAY DIFFRACTION	127	chain 'Q' and (resid 178 through 191 )	Q	178 - 191
128	X-RAY DIFFRACTION	128	chain 'Q' and (resid 192 through 202 )	Q	192 - 202
129	X-RAY DIFFRACTION	129	chain 'Q' and (resid 203 through 261 )	Q	203 - 261
130	X-RAY DIFFRACTION	130	chain 'Q' and (resid 262 through 281 )	Q	262 - 281
131	X-RAY DIFFRACTION	131	chain 'R' and (resid 113 through 132 )	R	113 - 132
132	X-RAY DIFFRACTION	132	chain 'R' and (resid 133 through 177 )	R	133 - 177
133	X-RAY DIFFRACTION	133	chain 'R' and (resid 178 through 191 )	R	178 - 191
134	X-RAY DIFFRACTION	134	chain 'R' and (resid 192 through 231 )	R	192 - 231
135	X-RAY DIFFRACTION	135	chain 'R' and (resid 232 through 281 )	R	232 - 281
136	X-RAY DIFFRACTION	136	chain 'S' and (resid 113 through 154 )	S	113 - 154
137	X-RAY DIFFRACTION	137	chain 'S' and (resid 155 through 202 )	S	155 - 202
138	X-RAY DIFFRACTION	138	chain 'S' and (resid 203 through 261 )	S	203 - 261
139	X-RAY DIFFRACTION	139	chain 'S' and (resid 262 through 281 )	S	262 - 281
140	X-RAY DIFFRACTION	140	chain 'T' and (resid 113 through 122 )	T	113 - 122
141	X-RAY DIFFRACTION	141	chain 'T' and (resid 123 through 145 )	T	123 - 145
142	X-RAY DIFFRACTION	142	chain 'T' and (resid 146 through 161 )	T	146 - 161
143	X-RAY DIFFRACTION	143	chain 'T' and (resid 162 through 177 )	T	162 - 177
144	X-RAY DIFFRACTION	144	chain 'T' and (resid 178 through 191 )	T	178 - 191
145	X-RAY DIFFRACTION	145	chain 'T' and (resid 192 through 202 )	T	192 - 202
146	X-RAY DIFFRACTION	146	chain 'T' and (resid 203 through 219 )	T	203 - 219
147	X-RAY DIFFRACTION	147	chain 'T' and (resid 220 through 231 )	T	220 - 231
148	X-RAY DIFFRACTION	148	chain 'T' and (resid 232 through 261 )	T	232 - 261
149	X-RAY DIFFRACTION	149	chain 'T' and (resid 262 through 273 )	T	262 - 273
150	X-RAY DIFFRACTION	150	chain 'T' and (resid 274 through 281 )	T	274 - 281
151	X-RAY DIFFRACTION	151	chain 'V' and (resid 113 through 132 )	V	113 - 132
152	X-RAY DIFFRACTION	152	chain 'V' and (resid 133 through 145 )	V	133 - 145
153	X-RAY DIFFRACTION	153	chain 'V' and (resid 146 through 161 )	V	146 - 161
154	X-RAY DIFFRACTION	154	chain 'V' and (resid 162 through 177 )	V	162 - 177
155	X-RAY DIFFRACTION	155	chain 'V' and (resid 178 through 202 )	V	178 - 202
156	X-RAY DIFFRACTION	156	chain 'V' and (resid 203 through 231 )	V	203 - 231
157	X-RAY DIFFRACTION	157	chain 'V' and (resid 232 through 247 )	V	232 - 247
158	X-RAY DIFFRACTION	158	chain 'V' and (resid 248 through 264 )	V	248 - 264
159	X-RAY DIFFRACTION	159	chain 'V' and (resid 265 through 281 )	V	265 - 281
160	X-RAY DIFFRACTION	160	chain 'W' and (resid 113 through 122 )	W	113 - 122
161	X-RAY DIFFRACTION	161	chain 'W' and (resid 123 through 132 )	W	123 - 132
162	X-RAY DIFFRACTION	162	chain 'W' and (resid 133 through 145 )	W	133 - 145
163	X-RAY DIFFRACTION	163	chain 'W' and (resid 146 through 161 )	W	146 - 161
164	X-RAY DIFFRACTION	164	chain 'W' and (resid 162 through 177 )	W	162 - 177
165	X-RAY DIFFRACTION	165	chain 'W' and (resid 178 through 192 )	W	178 - 192
166	X-RAY DIFFRACTION	166	chain 'W' and (resid 193 through 203 )	W	193 - 203
167	X-RAY DIFFRACTION	167	chain 'W' and (resid 204 through 219 )	W	204 - 219
168	X-RAY DIFFRACTION	168	chain 'W' and (resid 220 through 247 )	W	220 - 247
169	X-RAY DIFFRACTION	169	chain 'W' and (resid 248 through 261 )	W	248 - 261
170	X-RAY DIFFRACTION	170	chain 'W' and (resid 262 through 281 )	W	262 - 281
171	X-RAY DIFFRACTION	171	chain 'X' and (resid 113 through 122 )	X	113 - 122
172	X-RAY DIFFRACTION	172	chain 'X' and (resid 123 through 145 )	X	123 - 145
173	X-RAY DIFFRACTION	173	chain 'X' and (resid 146 through 161 )	X	146 - 161
174	X-RAY DIFFRACTION	174	chain 'X' and (resid 162 through 177 )	X	162 - 177
175	X-RAY DIFFRACTION	175	chain 'X' and (resid 178 through 191 )	X	178 - 191
176	X-RAY DIFFRACTION	176	chain 'X' and (resid 192 through 219 )	X	192 - 219
177	X-RAY DIFFRACTION	177	chain 'X' and (resid 220 through 247 )	X	220 - 247
178	X-RAY DIFFRACTION	178	chain 'X' and (resid 248 through 273 )	X	248 - 273
179	X-RAY DIFFRACTION	179	chain 'X' and (resid 274 through 281 )	X	274 - 281
180	X-RAY DIFFRACTION	180	chain 'Y' and (resid 113 through 132 )	Y	113 - 132
181	X-RAY DIFFRACTION	181	chain 'Y' and (resid 133 through 145 )	Y	133 - 145
182	X-RAY DIFFRACTION	182	chain 'Y' and (resid 146 through 177 )	Y	146 - 177
183	X-RAY DIFFRACTION	183	chain 'Y' and (resid 178 through 192 )	Y	178 - 192
184	X-RAY DIFFRACTION	184	chain 'Y' and (resid 193 through 231 )	Y	193 - 231
185	X-RAY DIFFRACTION	185	chain 'Y' and (resid 232 through 261 )	Y	232 - 261
186	X-RAY DIFFRACTION	186	chain 'Y' and (resid 262 through 281 )	Y	262 - 281