- PDB-6csv: The structure of the Cep63-Cep152 heterotetrameric complex -
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基本情報
登録情報
データベース: PDB / ID: 6csv
タイトル
The structure of the Cep63-Cep152 heterotetrameric complex
要素
Centrosomal protein of 63 kDa,Centrosomal protein of 152 kDa
キーワード
CELL CYCLE / Centrosome / Complex / Hydrophobic
機能・相同性
機能・相同性情報
negative regulation of protein K63-linked ubiquitination / de novo centriole assembly involved in multi-ciliated epithelial cell differentiation / procentriole / deuterosome / procentriole replication complex / cell projection organization / pericentriolar material / centriole replication / centrosome duplication / centriolar satellite ...negative regulation of protein K63-linked ubiquitination / de novo centriole assembly involved in multi-ciliated epithelial cell differentiation / procentriole / deuterosome / procentriole replication complex / cell projection organization / pericentriolar material / centriole replication / centrosome duplication / centriolar satellite / spindle assembly / signal transduction in response to DNA damage / Loss of Nlp from mitotic centrosomes / Loss of proteins required for interphase microtubule organization from the centrosome / Recruitment of mitotic centrosome proteins and complexes / Recruitment of NuMA to mitotic centrosomes / Anchoring of the basal body to the plasma membrane / centriole / negative regulation of innate immune response / AURKA Activation by TPX2 / DNA damage checkpoint signaling / spindle pole / Regulation of PLK1 Activity at G2/M Transition / molecular adaptor activity / protein stabilization / cell division / centrosome / protein kinase binding / nucleoplasm / cytosol 類似検索 - 分子機能
Centrosomal protein Cep63/Deup1, N-terminal / Centrosomal protein of 63 kDa 類似検索 - ドメイン・相同性
Centrosomal protein of 152 kDa / Centrosomal protein of 63 kDa 類似検索 - 構成要素
A: Centrosomal protein of 63 kDa,Centrosomal protein of 152 kDa B: Centrosomal protein of 63 kDa,Centrosomal protein of 152 kDa C: Centrosomal protein of 63 kDa,Centrosomal protein of 152 kDa D: Centrosomal protein of 63 kDa,Centrosomal protein of 152 kDa
プロトコル: SINGLE WAVELENGTH / 単色(M)・ラウエ(L): M / 散乱光タイプ: x-ray
放射波長
波長: 0.9793 Å / 相対比: 1
反射
解像度: 2.5→19.93 Å / Num. obs: 19496 / % possible obs: 93.17 % / 冗長度: 4.9 % / Net I/σ(I): 15.82
反射 シェル
解像度: 2.5→2.54 Å
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解析
ソフトウェア
名称
バージョン
分類
REFMAC
5.8.0189
精密化
HKL-2000
データ収集
HKL-2000
データ削減
HKL-2000
データスケーリング
PHENIX
位相決定
Coot
モデル構築
精密化
構造決定の手法: 単波長異常分散 / 解像度: 2.5→19.926 Å / Cor.coef. Fo:Fc: 0.904 / Cor.coef. Fo:Fc free: 0.867 / SU B: 13.934 / SU ML: 0.3 / 交差検証法: THROUGHOUT / ESU R: 0.798 / ESU R Free: 0.388 / 詳細: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS