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Open data
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Basic information
Entry | Database: PDB / ID: 6blh | |||||||||
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Title | RSV G central conserved region bound to Fab CB017.5 | |||||||||
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![]() | VIRAL PROTEIN/IMMUNE SYSTEM / Antibody / RSV / Attachment / RSV G / VIRAL PROTEIN / VIRAL PROTEIN-IMMUNE SYSTEM complex | |||||||||
Function / homology | ![]() symbiont entry into host cell / virus-mediated perturbation of host defense response / virion attachment to host cell / host cell plasma membrane / virion membrane / extracellular region / membrane Similarity search - Function | |||||||||
Biological species | ![]() ![]() | |||||||||
Method | ![]() ![]() ![]() | |||||||||
![]() | Jones, H.G. / McLellan, J.S. / Langedijk, J.P. | |||||||||
![]() | ![]() Title: Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies. Authors: Jones, H.G. / Ritschel, T. / Pascual, G. / Brakenhoff, J.P.J. / Keogh, E. / Furmanova-Hollenstein, P. / Lanckacker, E. / Wadia, J.S. / Gilman, M.S.A. / Williamson, R.A. / Roymans, D. / van ...Authors: Jones, H.G. / Ritschel, T. / Pascual, G. / Brakenhoff, J.P.J. / Keogh, E. / Furmanova-Hollenstein, P. / Lanckacker, E. / Wadia, J.S. / Gilman, M.S.A. / Williamson, R.A. / Roymans, D. / van 't Wout, A.B. / Langedijk, J.P. / McLellan, J.S. | |||||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 118.6 KB | Display | ![]() |
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PDB format | ![]() | 87.5 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 454.6 KB | Display | ![]() |
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Full document | ![]() | 455.4 KB | Display | |
Data in XML | ![]() | 24.4 KB | Display | |
Data in CIF | ![]() | 36.7 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Related structure data | ![]() 6bliC ![]() 4hpyS ![]() 8fabS S: Starting model for refinement C: citing same article ( |
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Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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1 |
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Unit cell |
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Components on special symmetry positions |
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Components
#1: Antibody | Mass: 22837.125 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() |
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#2: Antibody | Mass: 25097.162 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() |
#3: Protein/peptide | Mass: 5183.040 Da / Num. of mol.: 1 / Source method: obtained synthetically Source: (synth.) ![]() References: UniProt: P27025 |
#4: Chemical | ChemComp-EDO / |
#5: Water | ChemComp-HOH / |
-Experimental details
-Experiment
Experiment | Method: ![]() |
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Sample preparation
Crystal | Density Matthews: 2.81 Å3/Da / Density % sol: 56.3 % / Description: Medium-sized, flat plates. |
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Crystal grow | Temperature: 293 K / Method: vapor diffusion, hanging drop / pH: 7.5 / Details: 23.7% Isopropanol, 11.85% PEG4k, 0.1M HEPES pH 7.5 |
-Data collection
Diffraction | Mean temperature: 100 K |
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Diffraction source | Source: ![]() ![]() ![]() |
Detector | Type: DECTRIS PILATUS3 S 6M / Detector: PIXEL / Date: Jul 20, 2016 |
Radiation | Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray |
Radiation wavelength | Wavelength: 0.979 Å / Relative weight: 1 |
Reflection | Resolution: 2→41.9 Å / Num. obs: 40222 / % possible obs: 98.5 % / Redundancy: 5.8 % / CC1/2: 0.988 / Net I/σ(I): 5.3 |
Reflection shell | Resolution: 2→2.05 Å / Redundancy: 6.1 % / Mean I/σ(I) obs: 1.8 / Num. unique obs: 2939 / CC1/2: 0.901 / % possible all: 98.7 |
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Processing
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Refinement | Method to determine structure: ![]() Starting model: 8FAB, 4HPY Resolution: 2→41.873 Å / SU ML: 0.19 / Cross valid method: FREE R-VALUE / σ(F): 1.38 / Phase error: 21.71
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Solvent computation | Shrinkage radii: 0.9 Å / VDW probe radii: 1.11 Å | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refinement step | Cycle: LAST / Resolution: 2→41.873 Å
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Refine LS restraints |
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LS refinement shell |
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